Hereditary nonpolyposis colorectal cancer overview: Difference between revisions
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{{Hereditary nonpolyposis colorectal cancer}} | {{Hereditary nonpolyposis colorectal cancer}} | ||
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==Overview== | ==Overview== | ||
'''Hereditary nonpolyposis colorectal cancer''' | '''Hereditary nonpolyposis colorectal cancer''' is characterized by an increased risk of [[colorectal cancer]] and other cancers of the [[Endometrial cancer|endometrium]], [[Ovarian cancer|ovary]], [[Stomach cancer|stomach]], [[Gastrointestinal cancer|small intestine]], [[Gallbladder cancer|hepatobiliary tract]], upper urinary tract, [[Brain tumor|brain]], and [[Skin cancer|skin]]. HNPCC is subdivided into '''Lynch Syndrome I''' (familial colon cancer) and '''Lynch Syndrome II''' (other cancer of the gastrointestinal system or the reproductive system). The increased risk for these cancers is due to inherited mutations that degrade the self-repair capability of [[DNA]]. | ||
Lynch syndrome was named in honor of Dr. Henry T. Lynch, professor of medicine at Creighton University Medical Center.<ref>http://medicine.creighton.edu/HCC/Welcome%20DrL.htm</ref> | Lynch syndrome was named in honor of Dr. Henry T. Lynch, professor of medicine at Creighton University Medical Center.<ref>http://medicine.creighton.edu/HCC/Welcome%20DrL.htm</ref> | ||
==References== | ==References== | ||
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[[Category:Disease]] | [[Category:Disease]] | ||
[[Category:Types of cancer]] | [[Category:Types of cancer]] | ||
[[Category:Oncology]] | [[Category:Oncology]] | ||
[[Category:Gastroenterology]] | [[Category:Gastroenterology]] |
Revision as of 16:37, 18 September 2012
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Hereditary nonpolyposis colorectal cancer is characterized by an increased risk of colorectal cancer and other cancers of the endometrium, ovary, stomach, small intestine, hepatobiliary tract, upper urinary tract, brain, and skin. HNPCC is subdivided into Lynch Syndrome I (familial colon cancer) and Lynch Syndrome II (other cancer of the gastrointestinal system or the reproductive system). The increased risk for these cancers is due to inherited mutations that degrade the self-repair capability of DNA.
Lynch syndrome was named in honor of Dr. Henry T. Lynch, professor of medicine at Creighton University Medical Center.[1]