Hereditary nonpolyposis colorectal cancer overview: Difference between revisions
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Lynch syndrome was named in honor of Dr. Henry T. Lynch, professor of medicine at Creighton University Medical Center.<ref>http://medicine.creighton.edu/HCC/Welcome%20DrL.htm</ref> | Lynch syndrome was named in honor of Dr. Henry T. Lynch, professor of medicine at Creighton University Medical Center.<ref>http://medicine.creighton.edu/HCC/Welcome%20DrL.htm</ref> | ||
==Diagnosis== | |||
The Amsterdam clinical criteria identifies candidates for [[genetic testing]], and [[genetic testing]] can make a diagnosis of Lynch syndrome. [[Genetic testing]] is commercially available through [[Myriad Genetics]], and consists of a blood test. | |||
==References== | ==References== | ||
Revision as of 19:58, 21 January 2012
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Hereditary Nonpolyposis Colorectal Cancer Microchapters |
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Differentiating Hereditary Nonpolyposis Colorectal Cancer from other Diseases |
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Diagnosis |
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Treatment |
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Case Studies |
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Hereditary nonpolyposis colorectal cancer overview On the Web |
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American Roentgen Ray Society Images of Hereditary nonpolyposis colorectal cancer overview |
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Hereditary nonpolyposis colorectal cancer overview in the news |
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Directions to Hospitals Treating Hereditary nonpolyposis colorectal cancer |
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Risk calculators and risk factors for Hereditary nonpolyposis colorectal cancer overview |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Hereditary nonpolyposis colorectal cancer (HNPCC), also known as Lynch syndrome, is characterized by an increased risk of colorectal cancer and other cancers of the endometrium, ovary, stomach, small intestine, hepatobiliary tract, upper urinary tract, brain, and skin. HNPCC is subdivided into Lynch Syndrome I (familial colon cancer) and Lynch Syndrome II (other cancer of the gastrointestinal system or the reproductive system). The increased risk for these cancers is due to inherited mutations that degrade the self-repair capability of DNA.
Lynch syndrome was named in honor of Dr. Henry T. Lynch, professor of medicine at Creighton University Medical Center.[1]
Diagnosis
The Amsterdam clinical criteria identifies candidates for genetic testing, and genetic testing can make a diagnosis of Lynch syndrome. Genetic testing is commercially available through Myriad Genetics, and consists of a blood test.