Hereditary nonpolyposis colorectal cancer overview: Difference between revisions
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==Overview== | ==[[Hereditary nonpolyposis colorectal cancer overview|Overview]]== | ||
'''Hereditary nonpolyposis colorectal cancer''' is characterized by an increased risk of [[colorectal cancer]] and other cancers of the [[Endometrial cancer|endometrium]], [[Ovarian cancer|ovary]], [[Stomach cancer|stomach]], [[Gastrointestinal cancer|small intestine]], [[Gallbladder cancer|hepatobiliary tract]], upper urinary tract, [[Brain tumor|brain]], and [[Skin cancer|skin]]. HNPCC is subdivided into '''Lynch Syndrome I''' (familial colon cancer) and '''Lynch Syndrome II''' (other cancer of the gastrointestinal system or the reproductive system). The increased risk for these cancers is due to inherited mutations that degrade the self-repair capability of [[DNA]]. | '''Hereditary nonpolyposis colorectal cancer''' is characterized by an increased risk of [[colorectal cancer]] and other cancers of the [[Endometrial cancer|endometrium]], [[Ovarian cancer|ovary]], [[Stomach cancer|stomach]], [[Gastrointestinal cancer|small intestine]], [[Gallbladder cancer|hepatobiliary tract]], upper urinary tract, [[Brain tumor|brain]], and [[Skin cancer|skin]]. HNPCC is subdivided into '''Lynch Syndrome I''' (familial colon cancer) and '''Lynch Syndrome II''' (other cancer of the gastrointestinal system or the reproductive system). The increased risk for these cancers is due to inherited mutations that degrade the self-repair capability of [[DNA]]. | ||
==[[Hereditary nonpolyposis colorectal cancer historical perspective|Historical Perspective]]== | |||
==[[Hereditary nonpolyposis colorectal cancer classification|Classification]]== | |||
==[[Hereditary nonpolyposis colorectal cancer pathophysiology|Pathophysiology]]== | |||
==[[Hereditary nonpolyposis colorectal cancer causes|Causes]]== | |||
==[[Hereditary nonpolyposis colorectal cancer differential diagnosis|Differentiating Hereditary nonpolyposis colorectal cancer from other Diseases]]== | |||
==[[Hereditary nonpolyposis colorectal cancer epidemiology and demographics|Epidemiology and Demographics]]== | |||
==[[Hereditary nonpolyposis colorectal cancer risk factors|Risk Factors]]== | |||
==[[Hereditary nonpolyposis colorectal cancer natural history|Natural History, Complications and Prognosis]]== | |||
==Diagnosis== | |||
[[Hereditary nonpolyposis colorectal cancer staging|Staging]] | [[Hereditary nonpolyposis colorectal cancer history and symptoms|History and Symptoms]] | [[Hereditary nonpolyposis colorectal cancer physical examination|Physical Examination]] | [[Hereditary nonpolyposis colorectal cancer laboratory tests|Laboratory Findings]] | [[Hereditary nonpolyposis colorectal cancer electrocardiogram|Electrocardiogram]] | [[Hereditary nonpolyposis colorectal cancer chest x ray|Chest X Ray]] | [[Hereditary nonpolyposis colorectal cancer CT|CT]] | [[Hereditary nonpolyposis colorectal cancer MRI|MRI]] | [[Hereditary nonpolyposis colorectal cancer echocardiography or ultrasound|Echocardiography or Ultrasound]] | [[Hereditary nonpolyposis colorectal cancer other imaging findings|Other Imaging Findings]] | [[Hereditary nonpolyposis colorectal cancer other diagnostic studies|Other Diagnostic Studies]] | |||
==Treatment== | |||
[[Hereditary nonpolyposis colorectal cancer medical therapy|Medical Therapy]] | [[Hereditary nonpolyposis colorectal cancer surgery|Surgery]] | [[Hereditary nonpolyposis colorectal cancer cost-effectiveness of therapy|Cost-Effectiveness of Therapy]] | [[Hereditary nonpolyposis colorectal cancer future or investigational therapies|Future or Investigational Therapies]] | |||
==Case Studies== | |||
[[Hereditary nonpolyposis colorectal cancer case study one|Case #1]] | |||
== See also == | |||
* [[Colon cancer]] | |||
==References== | |||
{{Reflist|1}} | |||
{{WikiDoc Help Menu}} | |||
{{WikiDoc Sources}} | |||
[[Category:Disease]] | |||
[[Category:Gastrointestinal]] | |||
[[Category:Oncology]] | |||
==References== | ==References== | ||
Revision as of 16:30, 1 December 2015
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Differentiating Hereditary Nonpolyposis Colorectal Cancer from other Diseases |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Maria Fernanda Villarreal, M.D. [2]
Overview
Hereditary nonpolyposis colorectal cancer is characterized by an increased risk of colorectal cancer and other cancers of the endometrium, ovary, stomach, small intestine, hepatobiliary tract, upper urinary tract, brain, and skin. HNPCC is subdivided into Lynch Syndrome I (familial colon cancer) and Lynch Syndrome II (other cancer of the gastrointestinal system or the reproductive system). The increased risk for these cancers is due to inherited mutations that degrade the self-repair capability of DNA.
Historical Perspective
Classification
Pathophysiology
Causes
Differentiating Hereditary nonpolyposis colorectal cancer from other Diseases
Epidemiology and Demographics
Risk Factors
Natural History, Complications and Prognosis
Diagnosis
Staging | History and Symptoms | Physical Examination | Laboratory Findings | Electrocardiogram | Chest X Ray | CT | MRI | Echocardiography or Ultrasound | Other Imaging Findings | Other Diagnostic Studies
Treatment
Medical Therapy | Surgery | Cost-Effectiveness of Therapy | Future or Investigational Therapies