Hereditary nonpolyposis colorectal cancer other diagnostic studies: Difference between revisions
No edit summary |
|||
Line 20: | Line 20: | ||
The Amsterdam clinical criteria identifies candidates for [[genetic testing]], and [[genetic testing]] can make a diagnosis of Lynch syndrome. [[Genetic testing]] is commercially available through [[Myriad Genetics]], and consists of a blood test.<ref name="hpcc">Vasen HF, Watson P, Mecklin JP, Lynch HT. New clinical criteria for hereditary nonpolyposis colorectal cancer (HNPCC, Lynch syndrome) proposed by the International Collaborative group on HNPCC. Gastroenterology. 1999;116(6):1453-6.</ref> | The Amsterdam clinical criteria identifies candidates for [[genetic testing]], and [[genetic testing]] can make a diagnosis of Lynch syndrome. [[Genetic testing]] is commercially available through [[Myriad Genetics]], and consists of a blood test.<ref name="hpcc">Vasen HF, Watson P, Mecklin JP, Lynch HT. New clinical criteria for hereditary nonpolyposis colorectal cancer (HNPCC, Lynch syndrome) proposed by the International Collaborative group on HNPCC. Gastroenterology. 1999;116(6):1453-6.</ref> | ||
==References== | ==References== |
Revision as of 17:23, 4 December 2015
Hereditary Nonpolyposis Colorectal Cancer Microchapters |
Differentiating Hereditary Nonpolyposis Colorectal Cancer from other Diseases |
---|
Diagnosis |
Treatment |
Case Studies |
Hereditary nonpolyposis colorectal cancer other diagnostic studies On the Web |
American Roentgen Ray Society Images of Hereditary nonpolyposis colorectal cancer other diagnostic studies |
FDA on Hereditary nonpolyposis colorectal cancer other diagnostic studies |
CDC on Hereditary nonpolyposis colorectal cancer other diagnostic studies |
Hereditary nonpolyposis colorectal cancer other diagnostic studies in the news |
Blogs on Hereditary nonpolyposis colorectal cancer other diagnostic studies |
Directions to Hospitals Treating Hereditary nonpolyposis colorectal cancer |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Diagnostic and screening endoscopy is recommended in the case of HNPCC.[1] According to the American College of Gastroenterology, patients with HNPCC should undergo colonoscopy every 2 years beginning at age 20–25 years, until age 40 years, then annually thereafter.[2]
Other Diagnostic Studies
Diagnostic and screening colonoscopy is recommended in the case of HNPCC. In addition, annual upper endoscopy is highly suggested in families with gastric cancer.[3]
Colonoscopy
Patients with HNPCC should undergo colonoscopy every 2 years beginning at age 20–25 years, until age 40 years, then annually thereafter.[2]
ACG Guidelines - Colorectal Cancer Screening
Patients with positive tests can be offered genetic testing and when genetic testing is positive in a proband, at risk family members can be offered genetic testing. Those patients with positive genetic testing, or those at risk when genetic testing is unsuccessful in an affected proband, should undergo colonoscopy every 2 years beginning at age 20–25 years, until age 40 years, then annually thereafter (Grade 2 B). [2]
Genetic testing
The Amsterdam clinical criteria identifies candidates for genetic testing, and genetic testing can make a diagnosis of Lynch syndrome. Genetic testing is commercially available through Myriad Genetics, and consists of a blood test.[3]
References
- ↑ Kladny J, Lubinski J. Lynch syndrome (HNPCC). Hered Cancer Clin Pract. 2008;6(2):99-102.
- ↑ 2.0 2.1 2.2 Rex DK, Johnson DA, Lieberman DA et al. Colorectal cancer prevention 2000: screening recommendations of the American College of Gastroenterology. Am J Gastroenterol 2000;95:868–77.
- ↑ 3.0 3.1 Vasen HF, Watson P, Mecklin JP, Lynch HT. New clinical criteria for hereditary nonpolyposis colorectal cancer (HNPCC, Lynch syndrome) proposed by the International Collaborative group on HNPCC. Gastroenterology. 1999;116(6):1453-6.