Hereditary nonpolyposis colorectal cancer medical therapy

Revision as of 03:50, 24 January 2019 by Ali Akram (talk | contribs)
Jump to navigation Jump to search

Hereditary Nonpolyposis Colorectal Cancer Microchapters

Home

Patient Information

Overview

Historical Perspective

Classification

Pathophysiology

Causes

Differentiating Hereditary Nonpolyposis Colorectal Cancer from other Diseases

Epidemiology and Demographics

Risk Factors

Screening

Natural History, Complications and Prognosis

Diagnosis

Diagnostic Study of Choice

History and Symptoms

Physical Examination

Laboratory Findings

Electrocardiogram

X-ray

Echocardiography and Ultrasound

CT scan

MRI

Other Imaging Findings

Other Diagnostic Studies

Treatment

Medical Therapy

Surgery

Primary Prevention

Secondary Prevention

Cost-Effectiveness of Therapy

Future or Investigational Therapies

Case Studies

Case #1

Hereditary nonpolyposis colorectal cancer medical therapy On the Web

Most recent articles

Most cited articles

Review articles

CME Programs

Powerpoint slides

Images

American Roentgen Ray Society Images of Hereditary nonpolyposis colorectal cancer medical therapy

All Images
X-rays
Echo & Ultrasound
CT Images
MRI

Ongoing Trials at Clinical Trials.gov

US National Guidelines Clearinghouse

NICE Guidance

FDA on Hereditary nonpolyposis colorectal cancer medical therapy

CDC on Hereditary nonpolyposis colorectal cancer medical therapy

Hereditary nonpolyposis colorectal cancer medical therapy in the news

Blogs on Hereditary nonpolyposis colorectal cancer medical therapy

Directions to Hospitals Treating Hereditary nonpolyposis colorectal cancer

Risk calculators and risk factors for Hereditary nonpolyposis colorectal cancer medical therapy

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Maria Fernanda Villarreal, M.D. [2]

Overview

There is no medical treatment for hereditary nonpolyposis colorectal cancer.[1][2] However, hereditary nonpolyposis colorectal cancer patients should consider diet optimization and pharmacological prevention.

Medical Therapy

Patients with hereditary nonpolyposis colorectal cancer should consider the following options of medical management:[3]

Diet Optimization

  • Patients with high risk of colorectal cancer should consider a low fat diet with limitations concerning red meat.[4][5]
  • Dietary approaches should consider the inclusion of high fiber and rich in cellulose foods.

Pharmacological Prevention

  • Drugs lowering the risk of colorectal cancer include:[6][7][8]

The real value of these drugs in cancer prevention in hereditary nonpolyposis colorectal cancer cannot be excluded, but is not proven.

References

  1. Si JW, Wang L, Ba XJ, Zhang X, Dong Y, Zhang JX, Li WT, Li T (2015). "[Clinicopathological screening of Lynch syndrome: a report of 2 cases and literature review]". Beijing Da Xue Xue Bao (in Chinese). 47 (5): 858–64. PMID 26474631.
  2. Hendriks YM, de Jong AE, Morreau H, Tops CM, Vasen HF, Wijnen JT, Breuning MH, Bröcker-Vriends AH (2006). "Diagnostic approach and management of Lynch syndrome (hereditary nonpolyposis colorectal carcinoma): a guide for clinicians". CA Cancer J Clin. 56 (4): 213–25. PMID 16870997.
  3. Kladny J, Lubinski J. Lynch syndrome (HNPCC). Hered Cancer Clin Pract. 2008;6(2):99-102.
  4. W. C. Willett, M. J. Stampfer, G. A. Colditz, B. A. Rosner & F. E. Speizer (1990). "Relation of meat, fat, and fiber intake to the risk of colon cancer in a prospective study among women". The New England journal of medicine. 323 (24): 1664–1672. doi:10.1056/NEJM199012133232404. PMID 2172820. Unknown parameter |month= ignored (help)
  5. Jozef Kladny & Jan Lubinski (2008). "Lynch syndrome (HNPCC)". Hereditary cancer in clinical practice. 6 (2): 99–102. doi:10.1186/1897-4287-6-2-99. PMID 19804605. Unknown parameter |month= ignored (help)
  6. H. T. Lynch & J. Lynch (2000). "Lynch syndrome: genetics, natural history, genetic counseling, and prevention". Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 18 (21 Suppl): 19S–31S. PMID 11060321. Unknown parameter |month= ignored (help)
  7. Matthew B. Yurgelun & Heather Hampel (2018). "Recent Advances in Lynch Syndrome: Diagnosis, Treatment, and Cancer Prevention". American Society of Clinical Oncology educational book. American Society of Clinical Oncology. Annual Meeting (38): 101–109. doi:10.1200/EDBK_208341. PMID 30231390. Unknown parameter |month= ignored (help)
  8. Jozef Kladny & Jan Lubinski (2008). "Lynch syndrome (HNPCC)". Hereditary cancer in clinical practice. 6 (2): 99–102. doi:10.1186/1897-4287-6-2-99. PMID 19804605. Unknown parameter |month= ignored (help)


Template:WikiDoc Sources