Hereditary nonpolyposis colorectal cancer laboratory tests: Difference between revisions
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{{Hereditary nonpolyposis colorectal cancer}} | {{Hereditary nonpolyposis colorectal cancer}} | ||
{{CMG}}{{AE}}{{MV}} | {{CMG}}{{AE}}{{MV}}{{Akram}} | ||
==Overview== | ==Overview== | ||
Laboratory findings consistent with the diagnosis of hereditary nonpolyposis colorectal cancer, may include: positive germline testing for hereditary nonpolyposis colorectal cancer genes ([[MLH1]], [[MSH2]], [[MSH6]], and [[PMS2]]), positive EPCAM gene testing, and elevated serum concentration of [[CEA]] and [[CA-125]]. | Laboratory findings consistent with the diagnosis of hereditary nonpolyposis colorectal cancer, may include: positive germline testing for hereditary nonpolyposis colorectal cancer genes ([[MLH1]], [[MSH2]], [[MSH6]], and [[PMS2]]), positive EPCAM gene testing, and elevated serum concentration of [[CEA]] and [[CA-125]]. | ||
==Laboratory tests== | ==Laboratory tests== | ||
Laboratory findings consistent with the diagnosis of hereditary nonpolyposis colorectal cancer, may include: | Laboratory findings consistent with the diagnosis of hereditary nonpolyposis colorectal cancer, may include:<ref name="pmid24827900">{{cite journal |vauthors=Lynch HT, Drescher K, Knezetic J, Lanspa S |title=Genetics, biomarkers, hereditary cancer syndrome diagnosis, heterogeneity and treatment: a review |journal=Curr Treat Options Oncol |volume=15 |issue=3 |pages=429–42 |year=2014 |pmid=24827900 |doi=10.1007/s11864-014-0293-5 |url=}}</ref> | ||
:*Positive EPCAM gene | :*Positive EPCAM gene | ||
Revision as of 18:49, 13 February 2019
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Maria Fernanda Villarreal, M.D. [2]Ali Akram, M.B.B.S.[3]
Overview
Laboratory findings consistent with the diagnosis of hereditary nonpolyposis colorectal cancer, may include: positive germline testing for hereditary nonpolyposis colorectal cancer genes (MLH1, MSH2, MSH6, and PMS2), positive EPCAM gene testing, and elevated serum concentration of CEA and CA-125.
Laboratory tests
Laboratory findings consistent with the diagnosis of hereditary nonpolyposis colorectal cancer, may include:[1]
References
- ↑ Lynch HT, Drescher K, Knezetic J, Lanspa S (2014). "Genetics, biomarkers, hereditary cancer syndrome diagnosis, heterogeneity and treatment: a review". Curr Treat Options Oncol. 15 (3): 429–42. doi:10.1007/s11864-014-0293-5. PMID 24827900.