Hereditary nonpolyposis colorectal cancer history and symptoms: Difference between revisions
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==Overview== | ==Overview== | ||
The hallmark of hereditary nonpolyposis colorectal cancer is a first-degree relative of those with known MMR/EPCAM gene mutation. A positive history of colorectal cancer and meeting Amsterdam I or II criteria or revised Bethesda guidelines is highly suggestive of HNPCC. The most common symptoms include abdominal pain, weight loss and fatigue. | |||
==History and symptoms== | ==History and symptoms== | ||
==References== | ==References== | ||
{{reflist|2}} | {{reflist|2}} |
Revision as of 19:39, 3 December 2015
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Maria Fernanda Villarreal, M.D. [2]
Overview
The hallmark of hereditary nonpolyposis colorectal cancer is a first-degree relative of those with known MMR/EPCAM gene mutation. A positive history of colorectal cancer and meeting Amsterdam I or II criteria or revised Bethesda guidelines is highly suggestive of HNPCC. The most common symptoms include abdominal pain, weight loss and fatigue.