Hereditary nonpolyposis colorectal cancer historical perspective: Difference between revisions
No edit summary |
No edit summary |
||
Line 10: | Line 10: | ||
==Historical Perspective== | ==Historical Perspective== | ||
*In 1913, Aldred Warthin, Chairman of the Department of Pathology at the University of Michigan in Ann Arbor, first reported a family which he called 'Family G' with features of the disease now known as Lynch syndrome.<ref>{{Cite journal | *In 1913, Aldred Warthin, Chairman of the Department of Pathology at the University of Michigan in Ann Arbor, first reported a family which he called 'Family G' with features of the disease now known as Lynch syndrome. He recognized there were "cancer fraternities" and there was an influence of heredity on cancer.<ref>{{Cite journal | ||
| author = [[C. Richard Boland]] & [[Henry T. Lynch]] | | author = [[C. Richard Boland]] & [[Henry T. Lynch]] | ||
| title = The history of Lynch syndrome | | title = The history of Lynch syndrome |
Revision as of 17:37, 27 December 2018
Hereditary Nonpolyposis Colorectal Cancer Microchapters |
Differentiating Hereditary Nonpolyposis Colorectal Cancer from other Diseases |
---|
Diagnosis |
Treatment |
Case Studies |
Hereditary nonpolyposis colorectal cancer historical perspective On the Web |
American Roentgen Ray Society Images of Hereditary nonpolyposis colorectal cancer historical perspective |
FDA on Hereditary nonpolyposis colorectal cancer historical perspective |
CDC on Hereditary nonpolyposis colorectal cancer historical perspective |
Hereditary nonpolyposis colorectal cancer historical perspective in the news |
Blogs on Hereditary nonpolyposis colorectal cancer historical perspective |
Directions to Hospitals Treating Hereditary nonpolyposis colorectal cancer |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Maria Fernanda Villarreal, M.D. [2]
Overview
Lynch syndrome was first described by Dr. Henry T. Lynch, an American physician, in 1966.[1]
Overview
Historical Perspective
- In 1913, Aldred Warthin, Chairman of the Department of Pathology at the University of Michigan in Ann Arbor, first reported a family which he called 'Family G' with features of the disease now known as Lynch syndrome. He recognized there were "cancer fraternities" and there was an influence of heredity on cancer.[2]
- In 1966, Dr. Henry T. Lynch characterized Lynch syndrome for the first time.[3]
- Dr. Lynch discovered hereditary nonpolyposis colorectal cancer, as the most common form of hereditary colorectal cancer.
- In his earlier work, he described the disease entity as "cancer family syndrome". He demonstrated the Mendelian inheritance pattern for certain breast and ovarian cancers, which laid the ground work for the identification of specific genes responsible for these familial cancers, such as BRCA1 and BRCA2.[4]
- In 1971, Lynch and Krush updated the studies of the family, in which the disease eventually became known as hereditary nonpolyposis colon cancer (HNPCC), also known as Lynch Syndrome.[5]
- The term "Lynch syndrome" was coined in 1984 by other authors; Lynch named the condition hereditary nonpolyposis colorectal cancer in 1985. Since then the two terms have been used interchangeably, until later advances in the understanding of the genetics of the disease led to the term hereditary nonpolyposis colorectal cancer falling out of favor.[6]
- Other sources reserve the term "Lynch syndrome" when there is a known DNA mismatch repair defect, and use the term "familial colorectal cancer type X" when the Amsterdam criteria are met but there is no known DNA mismatch repair defect.[7]
References
- ↑ Lynch HT, Lynch JF (1985). "Hereditary nonpolyposis colorectal cancer (Lynch syndromes I and II): a common genotype linked to oncogenes?". Med. Hypotheses. 18 (1): 19–28. PMID 4069033.
- ↑ C. Richard Boland & Henry T. Lynch (2013). "The history of Lynch syndrome". Familial cancer. 12 (2): 145–157. doi:10.1007/s10689-013-9637-8. PMID 23546821. Unknown parameter
|month=
ignored (help) - ↑ Lynch HT, Shaw MW, Magnuson CW, Larsen AL, Krush AJ (Feb 1966). "Hereditary factors in cancer. Study of two large midwestern kindreds". Archives of Internal Medicine. 117 (2): 206–12. doi:10.1001/archinte.117.2.206. PMID 5901552.
- ↑ Henry. T Lynch.Wikipedia https://en.wikipedia.org/wiki/Henry_T._Lynch Accessed on December 01, 2015
- ↑ Schlussel AT, Gagliano RA, Seto-Donlon S, Eggerding F, Donlon T, Berenberg J; et al. (2014). "The evolution of colorectal cancer genetics-Part 1: from discovery to practice". J Gastrointest Oncol. 5 (5): 326–35. doi:10.3978/j.issn.2078-6891.2014.069. PMC 4173047. PMID 25276405.
- ↑ Bellizzi AM, Frankel WL (Nov 2009). "Colorectal cancer due to deficiency in DNA mismatch repair function: a review". Advances in Anatomic Pathology. 16 (6): 405–17. doi:10.1097/PAP.0b013e3181bb6bdc. PMID 19851131.
- ↑ Lindor NM (Oct 2009). "Familial colorectal cancer type X: the other half of hereditary nonpolyposis colon cancer syndrome". Surgical Oncology Clinics of North America. 18 (4): 637–45. doi:10.1016/j.soc.2009.07.003. PMC 3454516. PMID 19793571.