Hepatocellular carcinoma epidemiology and demographics: Difference between revisions
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{{Hepatocellular carcinoma}} | {{Hepatocellular carcinoma}} | ||
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==Overview== | ==Overview== | ||
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==Developing Countries== | ==Developing Countries== | ||
In some parts of the world | In some parts of the world, such as sub-Saharan Africa and Southeast Asia, hepatocellular carcinoma is the most common cancer, generally affecting men more than women, and with an age of onset between late teens and 30s. This variability is in part due to the different patterns of [[hepatitis B]] transmission in different populations - infection at or around birth predispose to earlier cancers than if people are infected later. The time between hepatitis B infection and development into hepatocellular carcinoma can be years even decades, but from diagnosis of hepatocellular carcinoma to death the average survival period is only 5.9 months, according to one Chinese study during the 1970-80s, or 3 months ([[median]] survival time) in Sub-Saharan Africa according to Manson's textbook of tropical diseases. hepatocellular carcinoma is one of the deadliest cancers in China. | ||
==References== | ==References== | ||
Revision as of 15:42, 8 September 2015
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Mohamad Alkateb, MBBCh [2]
Overview
Hepatocellular carcinoma is the 5th most common tumor worldwide. The epidemiology of hepatocellular carcinoma exhibits two main patterns, one in North America and Western Europe and another in non-Western countries, such as those in sub-Saharan Africa, Central Asia and Southeast Asia, and the Amazon basin. Males are affected more than females usually and it is more common between the 3rd and 5th decades of life. Hepatocellular carcinoma causes 662,000 deaths worldwide per year.[1]
Age
Hepatocellular carcinoma is more common between the 3rd and 5th decades of life.
Gender
Males are more affected than females.
Developed Countries
Most malignant tumors of the liver discovered in Western patients are metastases from tumors elsewhere. In the West, hepatocellular carcinoma is generally seen as rare cancer, normally of those with pre-existing liver disease. It is often detected by ultrasound screening, and so can be discovered by health-care facilities much earlier than in developing regions such as Sub-Saharan Africa.
Developing Countries
In some parts of the world, such as sub-Saharan Africa and Southeast Asia, hepatocellular carcinoma is the most common cancer, generally affecting men more than women, and with an age of onset between late teens and 30s. This variability is in part due to the different patterns of hepatitis B transmission in different populations - infection at or around birth predispose to earlier cancers than if people are infected later. The time between hepatitis B infection and development into hepatocellular carcinoma can be years even decades, but from diagnosis of hepatocellular carcinoma to death the average survival period is only 5.9 months, according to one Chinese study during the 1970-80s, or 3 months (median survival time) in Sub-Saharan Africa according to Manson's textbook of tropical diseases. hepatocellular carcinoma is one of the deadliest cancers in China.