Heparin-induced thrombocytopenia natural history, complications and prognosis: Difference between revisions
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* Myocardial infarction: This is characterized by [[myocyte]] death due to ischemic injury from coronary artery occlusion. It is also known more commonly as a heart attack. | * Myocardial infarction: This is characterized by [[myocyte]] death due to ischemic injury from coronary artery occlusion. It is also known more commonly as a heart attack. | ||
* Skin necrosis<ref name="pmid22315270">{{cite journal| author=Linkins LA, Dans AL, Moores LK, Bona R, Davidson BL, Schulman S et al.| title=Treatment and prevention of heparin-induced thrombocytopenia: Antithrombotic Therapy and Prevention of Thrombosis, 9th ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines. | journal=Chest | year= 2012 | volume= 141 | issue= 2 Suppl | pages= e495S-e530S | pmid=22315270 | doi=10.1378/chest.11-2303 | pmc=3278058 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=22315270 }} </ref> | * Skin necrosis<ref name="pmid22315270">{{cite journal| author=Linkins LA, Dans AL, Moores LK, Bona R, Davidson BL, Schulman S et al.| title=Treatment and prevention of heparin-induced thrombocytopenia: Antithrombotic Therapy and Prevention of Thrombosis, 9th ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines. | journal=Chest | year= 2012 | volume= 141 | issue= 2 Suppl | pages= e495S-e530S | pmid=22315270 | doi=10.1378/chest.11-2303 | pmc=3278058 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=22315270 }} </ref> | ||
===DIC=== | |||
==Prognosis== | ==Prognosis== | ||
Revision as of 23:23, 8 July 2017
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Heparin-induced thrombocytopenia |
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Differentiating Heparin-induced thrombocytopenia from other Diseases |
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Diagnosis |
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Treatment |
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Case Studies |
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Heparin-induced thrombocytopenia natural history, complications and prognosis On the Web |
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Directions to Hospitals Treating Heparin-induced thrombocytopenia |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Shyam Patel [2]
Overview
Natural History
Complications
Complications of HIT are most thrombotic in nature. These can be quite devastating, which high morbidity and mortality. Venous thrombosis includes deep vein thrombosis (DVT) and pulmonary embolism (PE). Arterial thrombosis includes stroke and acute limb ischemia.
Venous thrombosis
- Deep vein thrombosis
- Pulmonary embolism[1]
- Post-phlebitis syndrome: This can occur after DVT and results in inflammation of the leg and its veins due to chronic occlusion.
- Cerebral venous sinus thrombosis
Arterial thrombosis
- Acute limb ischemia[1]: This can sometimes require limb amputation to prevent further tissue damage and sepsis from the thrombotic arm or leg.
- Stroke[1]
- Myocardial infarction: This is characterized by myocyte death due to ischemic injury from coronary artery occlusion. It is also known more commonly as a heart attack.
- Skin necrosis[1]
DIC
Prognosis
Reference
- ↑ 1.0 1.1 1.2 1.3 Linkins LA, Dans AL, Moores LK, Bona R, Davidson BL, Schulman S; et al. (2012). "Treatment and prevention of heparin-induced thrombocytopenia: Antithrombotic Therapy and Prevention of Thrombosis, 9th ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines". Chest. 141 (2 Suppl): e495S–e530S. doi:10.1378/chest.11-2303. PMC 3278058. PMID 22315270.