Hashimoto's thyroiditis causes

Hashimoto's thyroiditis Microchapters
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Furqan M M. M.B.B.S[2]

Overview

Hashimoto's thyroiditis may be caused by either T cells and B cells auto activation, genetic factors, and autoimmune antibodies against thyrotropin receptors.

Causes

The causes involved in the development of Hashimoto's thyroiditis are:

Common causes

• Autoantibodies against Thyroid peroxidase and thyroglobulin.
• Abnormalities in the suppressor T cells and regulatory T cells.
• HLA-B* 46:01, HLA-A* 02:07 and HLA-DRB4 involvement.

Less common cause

• Micro RNA involvement.
• Polyglandular diseases.

For the factors involved in the development of Hashimoto's thyroiditis, please click here.