Graft-versus-host disease physical examination: Difference between revisions
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Other physical exam findings are based on the particular organ involved. For example, if there is evidence of ocular GvHD, a full ophthalmologic exam should be done.<ref name="pmid25655798">{{cite journal| author=Herretes S, Ross DB, Duffort S, Barreras H, Yaohong T, Saeed AM et al.| title=Recruitment of Donor T Cells to the Eyes During Ocular GVHD in Recipients of MHC-Matched Allogeneic Hematopoietic Stem Cell Transplants. | journal=Invest Ophthalmol Vis Sci | year= 2015 | volume= 56 | issue= 4 | pages= 2348-57 | pmid=25655798 | doi=10.1167/iovs.14-15630 | pmc=4406104 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=25655798 }} </ref> | Other physical exam findings are based on the particular organ involved. For example, if there is evidence of ocular GvHD, a full ophthalmologic exam should be done.<ref name="pmid25655798">{{cite journal| author=Herretes S, Ross DB, Duffort S, Barreras H, Yaohong T, Saeed AM et al.| title=Recruitment of Donor T Cells to the Eyes During Ocular GVHD in Recipients of MHC-Matched Allogeneic Hematopoietic Stem Cell Transplants. | journal=Invest Ophthalmol Vis Sci | year= 2015 | volume= 56 | issue= 4 | pages= 2348-57 | pmid=25655798 | doi=10.1167/iovs.14-15630 | pmc=4406104 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=25655798 }} </ref> | ||
Revision as of 19:05, 21 June 2017
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Graft-versus-host disease |
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Differentiating Graft-versus-host disease from other Diseases |
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Diagnosis |
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Treatment |
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Case Studies |
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Graft-versus-host disease physical examination On the Web |
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American Roentgen Ray Society Images of Graft-versus-host disease physical examination |
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Risk calculators and risk factors for Graft-versus-host disease physical examination |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Shyam Patel [2]
Overview
The physical exam for GvHD focuses on the organ involved, including the skin, liver, and GI tract. The lungs can also be involved in more rare cases.
Physical Examination
Skin
Liver
- jaundice[1]
- pruritis[1]
- scleral icterus[1]
- leg swelling[1]
- tenderness in the right upper quadrant of the abdomen[1]
- bleeding from coagulopathy[1]
- signs of cholestatic hepatitis[1]
GI tract
- abdominal tenderness
- diarrhea
- hyperactive or hypoactive bowel sounds
Lungs
- decreased breath sounds
- crackles (if fluid fills the alveolar space)
Other organs
Other physical exam findings are based on the particular organ involved. For example, if there is evidence of ocular GvHD, a full ophthalmologic exam should be done.[2]
References
- ↑ 1.00 1.01 1.02 1.03 1.04 1.05 1.06 1.07 1.08 1.09 1.10 Socié G, Ritz J (2014). "Current issues in chronic graft-versus-host disease". Blood. 124 (3): 374–84. doi:10.1182/blood-2014-01-514752. PMC 4102710. PMID 24914139.
- ↑ Herretes S, Ross DB, Duffort S, Barreras H, Yaohong T, Saeed AM; et al. (2015). "Recruitment of Donor T Cells to the Eyes During Ocular GVHD in Recipients of MHC-Matched Allogeneic Hematopoietic Stem Cell Transplants". Invest Ophthalmol Vis Sci. 56 (4): 2348–57. doi:10.1167/iovs.14-15630. PMC 4406104. PMID 25655798.