Graft-versus-host disease chest x ray: Difference between revisions

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==Chest X-Ray==
==Chest X-Ray==
Chest X-ray can be done to assess for immune attack in the lungs, such as [[pneumonitis]]. Pneumonitis is a less common GvHD manifestation compared to rash, liver dysfunction, and diarrhea. However, [[pneumonitis]] has been known to occur. CT scan of the chest can better diagnose pneumonitis. Pneumonitis presents radiographically as a nodular or interstitial pattern. There can be inflammation in the peri-bronchiolar tissue, resulting in variable areas of hyperdensity and hypodensity on the chest X-ray. Ground glass appearance and consolidative opacities can also be seen.<ref name="pmid26205737">{{cite journal| author=Nishino M, Boswell EN, Hatabu H, Ghobrial IM, Ramaiya NH| title=Drug-Related Pneumonitis During Mammalian Target of Rapamycin Inhibitor Therapy: Radiographic Pattern-Based Approach in Waldenström Macroglobulinemia as a Paradigm. | journal=Oncologist | year= 2015 | volume= 20 | issue= 9 | pages= 1077-83 | pmid=26205737 | doi=10.1634/theoncologist.2015-0033 | pmc=4571812 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=26205737  }} </ref>
Chest X-ray can be done to assess for immune attack in the lungs, such as [[pneumonitis]]. Pneumonitis is a less common GvHD manifestation compared to rash, liver dysfunction, and diarrhea. However, [[pneumonitis]] has been known to occur. Pneumonitis presents radiographically as a nodular or interstitial pattern. There can be inflammation in the peri-bronchiolar tissue, resulting in variable areas of hyperdensity and hypodensity on the chest X-ray. Ground glass appearance and consolidative opacities can also be seen.<ref name="pmid26205737">{{cite journal| author=Nishino M, Boswell EN, Hatabu H, Ghobrial IM, Ramaiya NH| title=Drug-Related Pneumonitis During Mammalian Target of Rapamycin Inhibitor Therapy: Radiographic Pattern-Based Approach in Waldenström Macroglobulinemia as a Paradigm. | journal=Oncologist | year= 2015 | volume= 20 | issue= 9 | pages= 1077-83 | pmid=26205737 | doi=10.1634/theoncologist.2015-0033 | pmc=4571812 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=26205737  }} </ref> CT scan of the chest can better diagnose pneumonitis.


==References==
==References==

Revision as of 00:07, 5 July 2017

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Shyam Patel [2]

Overview

A chest X-ray can be done to evaluate for pneumonitis, which can be a manifestation of pulmonary GvHD. A variety of radiographic features can be seen.

Chest X-Ray

Chest X-ray can be done to assess for immune attack in the lungs, such as pneumonitis. Pneumonitis is a less common GvHD manifestation compared to rash, liver dysfunction, and diarrhea. However, pneumonitis has been known to occur. Pneumonitis presents radiographically as a nodular or interstitial pattern. There can be inflammation in the peri-bronchiolar tissue, resulting in variable areas of hyperdensity and hypodensity on the chest X-ray. Ground glass appearance and consolidative opacities can also be seen.[1] CT scan of the chest can better diagnose pneumonitis.

References

  1. Nishino M, Boswell EN, Hatabu H, Ghobrial IM, Ramaiya NH (2015). "Drug-Related Pneumonitis During Mammalian Target of Rapamycin Inhibitor Therapy: Radiographic Pattern-Based Approach in Waldenström Macroglobulinemia as a Paradigm". Oncologist. 20 (9): 1077–83. doi:10.1634/theoncologist.2015-0033. PMC 4571812. PMID 26205737.

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