Gestational trophoblastic disease

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Gestational trophoblastic disease
DiseasesDB 2602
MedlinePlus 001496
MeSH D031901

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Gestational trophoblastic disease, usually referred to as a mole, is a very rare abnormality of pregnancy in the reproductive female that involves abnormal trophoblast proliferation.

It is the result of a (purely chance) genetic error during the fertilization process that in turn causes the growth of abnormal tissue (which is not an embryo) within the uterus. The growth of this material is disproportionately rapid when compared to normal fetal growth.

Types

There are profound differences in pathological morphology and clinical behavior in various forms of GTD. Types include:

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