Gastrointestinal stromal tumor historical perspective: Difference between revisions
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{{Gastrointestinal stromal tumor}} | {{Gastrointestinal stromal tumor}} | ||
{{CMG}} | {{CMG}} | ||
==Overview== | |||
==Historical Perspective== | ==Historical Perspective== | ||
Until the 1990s, all non-[[epithelium|epithelial]] [[tumor]]s of the [[gastrointestinal tract]] were called "gastrointestinal stromal tumors" from [[smooth muscle]] origin. [[Histopathology|Histopathologists]] generally did not distinguish between the types, as this did affect neither therapy nor prognosis. Subsequently, [[Cluster of differentiation|CD34]], and later CD117 were identified as markers that could distinguish the various types. | Until the 1990s, all non-[[epithelium|epithelial]] [[tumor]]s of the [[gastrointestinal tract]] were called "gastrointestinal stromal tumors" from [[smooth muscle]] origin. [[Histopathology|Histopathologists]] generally did not distinguish between the types, as this did affect neither therapy nor prognosis. Subsequently, [[Cluster of differentiation|CD34]], and later CD117 were identified as markers that could distinguish the various types. |
Revision as of 20:00, 2 September 2015
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Differentiating Gastrointestinal stromal tumor from other Diseases |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Historical Perspective
Until the 1990s, all non-epithelial tumors of the gastrointestinal tract were called "gastrointestinal stromal tumors" from smooth muscle origin. Histopathologists generally did not distinguish between the types, as this did affect neither therapy nor prognosis. Subsequently, CD34, and later CD117 were identified as markers that could distinguish the various types.