Gastrointestinal stromal tumor MRI: Difference between revisions

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==MRI==
==MRI==
* MRI is more accurate and sensitive than a CT scan for delineating '''rectal''' GISTs. For GISTs located at other locations MRI is as sensitive as a CT scan.  
* MRI is more accurate and sensitive than a CT scan for delineating '''rectal''' GISTs. For GISTs located at other locations MRI is as sensitive as a CT scan.  
*MRI is more accurate than CT for delineating rectal GISTs and in detecting liver [[metastasis]], [[hemorrhage]] and [[necrosis]].
* MRI is also more sensitive in identifying GIST associated hemorrhage, necrosis, surrounding structures and metastasis.<ref name="pmid15648083">{{cite journal |vauthors=Nilsson B, Bümming P, Meis-Kindblom JM, Odén A, Dortok A, Gustavsson B, Sablinska K, Kindblom LG |title=Gastrointestinal stromal tumors: the incidence, prevalence, clinical course, and prognostication in the preimatinib mesylate era--a population-based study in western Sweden |journal=Cancer |volume=103 |issue=4 |pages=821–9 |year=2005 |pmid=15648083 |doi=10.1002/cncr.20862 |url=}}</ref><ref name="pmid14645423">{{cite journal |vauthors=Heinrich MC, Corless CL, Demetri GD, Blanke CD, von Mehren M, Joensuu H, McGreevey LS, Chen CJ, Van den Abbeele AD, Druker BJ, Kiese B, Eisenberg B, Roberts PJ, Singer S, Fletcher CD, Silberman S, Dimitrijevic S, Fletcher JA |title=Kinase mutations and imatinib response in patients with metastatic gastrointestinal stromal tumor |journal=J. Clin. Oncol. |volume=21 |issue=23 |pages=4342–9 |year=2003 |pmid=14645423 |doi=10.1200/JCO.2003.04.190 |url=}}</ref>
* MRI is also more sensitive in identifying GIST associated hemorrhage, necrosis, surrounding structures and metastasis.<ref name="pmid15648083">{{cite journal |vauthors=Nilsson B, Bümming P, Meis-Kindblom JM, Odén A, Dortok A, Gustavsson B, Sablinska K, Kindblom LG |title=Gastrointestinal stromal tumors: the incidence, prevalence, clinical course, and prognostication in the preimatinib mesylate era--a population-based study in western Sweden |journal=Cancer |volume=103 |issue=4 |pages=821–9 |year=2005 |pmid=15648083 |doi=10.1002/cncr.20862 |url=}}</ref><ref name="pmid14645423">{{cite journal |vauthors=Heinrich MC, Corless CL, Demetri GD, Blanke CD, von Mehren M, Joensuu H, McGreevey LS, Chen CJ, Van den Abbeele AD, Druker BJ, Kiese B, Eisenberg B, Roberts PJ, Singer S, Fletcher CD, Silberman S, Dimitrijevic S, Fletcher JA |title=Kinase mutations and imatinib response in patients with metastatic gastrointestinal stromal tumor |journal=J. Clin. Oncol. |volume=21 |issue=23 |pages=4342–9 |year=2003 |pmid=14645423 |doi=10.1200/JCO.2003.04.190 |url=}}</ref>
* On an MRI the the presence of hemorrhage, necrosis and cystic change may have variable appearances:
* On an MRI the the presence of hemorrhage, necrosis and cystic change may have variable appearances:

Revision as of 23:57, 17 December 2017

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Parminder Dhingra, M.D. [2]

Overview

MRI scan may be helpful in the diagnosis of gastrointestinal stromal tumor.

MRI

  • MRI is more accurate and sensitive than a CT scan for delineating rectal GISTs. For GISTs located at other locations MRI is as sensitive as a CT scan.
  • MRI is more accurate than CT for delineating rectal GISTs and in detecting liver metastasis, hemorrhage and necrosis.
  • MRI is also more sensitive in identifying GIST associated hemorrhage, necrosis, surrounding structures and metastasis.[1][2]
  • On an MRI the the presence of hemorrhage, necrosis and cystic change may have variable appearances:
    • On a T1 weighted MRI:
      • Low signal intensity indicates solid component GISTs.
      • With larger GISTs contrast induced enhancement is present and predominantly peripheral in larger lesions.
    • On a T2 weighted MRI
      • High signal intensity indicates solid component GISTs.

References

  1. Nilsson B, Bümming P, Meis-Kindblom JM, Odén A, Dortok A, Gustavsson B, Sablinska K, Kindblom LG (2005). "Gastrointestinal stromal tumors: the incidence, prevalence, clinical course, and prognostication in the preimatinib mesylate era--a population-based study in western Sweden". Cancer. 103 (4): 821–9. doi:10.1002/cncr.20862. PMID 15648083.
  2. Heinrich MC, Corless CL, Demetri GD, Blanke CD, von Mehren M, Joensuu H, McGreevey LS, Chen CJ, Van den Abbeele AD, Druker BJ, Kiese B, Eisenberg B, Roberts PJ, Singer S, Fletcher CD, Silberman S, Dimitrijevic S, Fletcher JA (2003). "Kinase mutations and imatinib response in patients with metastatic gastrointestinal stromal tumor". J. Clin. Oncol. 21 (23): 4342–9. doi:10.1200/JCO.2003.04.190. PMID 14645423.


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