Gallbladder cancer epidemiology and demographics: Difference between revisions

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==Overview==
==Overview==
In 2015, the number of new cases of gallbladder cancer was estimated to be 10,910 in United States. Females are more commonly affected with gallbladder cancer than males, the female to male ratio is approximately 5 to 1.
Around 80 t0 95% of biliary tract cancers are gallbladder cancers.Epidemiological research have recognized striking geographic and ethnic difference. An excessive incidence in American Indians and Southeast Asia, but pretty low some place else in the Americas and the arena.


==Epidemiology and Demographics==
==Epidemiology and Demographics==


*Estimated new cases and deaths from gallbladder (and other biliary) cancer in the United States in 2015
=== '''Incidence''' ===
:*New cases: 10,910
* The countries with high incidence have high mortality rate because mortality rate relatively follows incidence
:*Deaths: 3,700
* American Indian and Alaska Native people had the highest gallbladder cancer incidence.
 
=== Prevalence ===
* The incidence/prevalence of gallbladder cancer is approximately 21 per 100,000 cancer incidence and 75.8% gallstone prevalence in pima indian females.<ref name="pmid5481754">{{cite journal| author=Sampliner RE, Bennett PH, Comess LJ, Rose FA, Burch TA| title=Gallbladder disease in pima indians. Demonstration of high prevalence and early onset by cholecystography. | journal=N Engl J Med | year= 1970 | volume= 283 | issue= 25 | pages= 1358-64 | pmid=5481754 | doi=10.1056/NEJM197012172832502 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=5481754  }}</ref>
* The incidence/prevalence of gallbladder cancer is approximately 7.1 per 100,000 and 64.1% in North American Indian females.<ref name="pmid9753497">{{cite journal |vauthors=Miquel JF, Covarrubias C, Villaroel L, Mingrone G, Greco AV, Puglielli L, Carvallo P, Marshall G, Del Pino G, Nervi F |title=Genetic epidemiology of cholesterol cholelithiasis among Chilean Hispanics, Amerindians, and Maoris |journal=Gastroenterology |volume=115 |issue=4 |pages=937–46 |year=1998 |pmid=9753497 |doi= |url=}}</ref>
* The incidence/prevalence of gallbladder cancer is approximately 27.3 per 100,000 and 49.4%  in Chilean Mapuche Indian females.<ref name="pmid97534972">{{cite journal |vauthors=Miquel JF, Covarrubias C, Villaroel L, Mingrone G, Greco AV, Puglielli L, Carvallo P, Marshall G, Del Pino G, Nervi F |title=Genetic epidemiology of cholesterol cholelithiasis among Chilean Hispanics, Amerindians, and Maoris |journal=Gastroenterology |volume=115 |issue=4 |pages=937–46 |year=1998 |pmid=9753497 |doi= |url=}}</ref>
* The incidence/prevalence of gallbladder cancer is approximately  22 per 100,000 and 21.6% in East Indian females.


*Rare tumor, the U.S. incidence is 3 cases per 100,000 people each year
*Gallbladder cancer is more common in South American countries, Japan, and Israel. In Chile gallbladder cancer is the fourth most common cause of cancer deaths
*5th most common [[gastrointestinal cancer]]
*Up to 5 times more common in women than men depending on population (e.g. 73% female in China  <ref name="cn">{{cite journal |author=Hsing AW, Gao YT, Han TQ, ''et al.'' |title=Gallstones and the risk of biliary tract cancer: a population-based study in China |journal=Br. J. Cancer |volume=97 |issue=11 |pages=1577–82 |date=December 2007 |pmid=18000509 |pmc=2360257 |doi=10.1038/sj.bjc.6604047 }}</ref>)
* The age adjusted incidence rates of gall bladder cancer is highest in Chile followed by In the state of Assam in India
===Age===
===Age===
* Clinical data shows most people with gallbladder cancer are older than 70.
* Clinical data shows most people with gallbladder cancer are older than 70.

Revision as of 18:44, 12 January 2018

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Parminder Dhingra, M.D. [2]

Overview

Around 80 t0 95% of biliary tract cancers are gallbladder cancers.Epidemiological research have recognized striking geographic and ethnic difference. An excessive incidence in American Indians and Southeast Asia, but pretty low some place else in the Americas and the arena.

Epidemiology and Demographics

Incidence

  • The countries with high incidence have high mortality rate because mortality rate relatively follows incidence
  • American Indian and Alaska Native people had the highest gallbladder cancer incidence.

Prevalence

  • The incidence/prevalence of gallbladder cancer is approximately 21 per 100,000 cancer incidence and 75.8% gallstone prevalence in pima indian females.[1]
  • The incidence/prevalence of gallbladder cancer is approximately 7.1 per 100,000 and 64.1% in North American Indian females.[2]
  • The incidence/prevalence of gallbladder cancer is approximately 27.3 per 100,000 and 49.4% in Chilean Mapuche Indian females.[3]
  • The incidence/prevalence of gallbladder cancer is approximately 22 per 100,000 and 21.6% in East Indian females.

Age

  • Clinical data shows most people with gallbladder cancer are older than 70.
  • Gallbladder adenocarcinoma predominantly affects older persons with long-standing cholecystolithiasis.

Gender

  • Epidemiology data shows women are about twice as likely to develop gallbladder cancer as men.

Race

  • Epidemiology data demonstrates that Mexican Americans and Native Americans, particularly in the southwestern United States, are more likely to develop gallbladder cancer than the general population.

References

  1. Sampliner RE, Bennett PH, Comess LJ, Rose FA, Burch TA (1970). "Gallbladder disease in pima indians. Demonstration of high prevalence and early onset by cholecystography". N Engl J Med. 283 (25): 1358–64. doi:10.1056/NEJM197012172832502. PMID 5481754.
  2. Miquel JF, Covarrubias C, Villaroel L, Mingrone G, Greco AV, Puglielli L, Carvallo P, Marshall G, Del Pino G, Nervi F (1998). "Genetic epidemiology of cholesterol cholelithiasis among Chilean Hispanics, Amerindians, and Maoris". Gastroenterology. 115 (4): 937–46. PMID 9753497.
  3. Miquel JF, Covarrubias C, Villaroel L, Mingrone G, Greco AV, Puglielli L, Carvallo P, Marshall G, Del Pino G, Nervi F (1998). "Genetic epidemiology of cholesterol cholelithiasis among Chilean Hispanics, Amerindians, and Maoris". Gastroenterology. 115 (4): 937–46. PMID 9753497.


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