Focal segmental glomerulosclerosis differential diagnosis
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Differentiating Focal segmental glomerulosclerosis from other Diseases |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Differentiating Focal segmental glomerulosclerosis from other Diseases
Other renal causes of nephrotic syndrome should be in the differential diagnosis of focal segmental glomerulosclerosis (FSGS). Secondary causes of FSGS should also be ruled out before the diagnosis of primary (idiopathic) FSGS is made.
Segmental sclerosis may be seen in other renal diseases, such as[1]:
- IgA nephropathy
- IgM nephropathy
- C1q nephropathy
- Crescentic necrotizing glomerulonephritis
- Diabetic nephropathy
- Membranous nephropathy
Notably also, the pathological appearance of tip lesions is not specific. Other diseases that might show tip lesions include[2]:
- Minimal change disease
- IgA nephropathy
- Membranous nephropathy
- Diabetic glomerulosclerosis
References
- ↑ Thomas DB (2009). "Focal segmental glomerulosclerosis: a morphologic diagnosis in evolution". Arch Pathol Lab Med. 133 (2): 217–23. doi:10.1043/1543-2165-133.2.217. PMID 19195965 Check
|pmid=value (help). - ↑ D'Agati V (2003). "Pathologic classification of focal segmental glomerulosclerosis". Semin Nephrol. 23 (2): 117–34. doi:10.1053/snep.2003.50012. PMID 12704572.