Extranodal NK-T-cell lymphoma overview

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Sowminya Arikapudi, M.B,B.S. [2]

Overview

Extranodal NK-T-cell lymphoma is a type of lymphoma.[1] [2] [3] It is called "extranodal" to emphasize that the location is not in the lymph node. It is sometimes further qualified as "nasal type". It can be associated with Epstein Barr virus. [4] [5]

RNAi against EBNA1 has been proposed as a possible treatment. [6]

References

  1. ↑ Lee J, Suh C, Park YH; et al. (2006). "Extranodal natural killer T-cell lymphoma, nasal-type: a prognostic model from a retrospective multicenter study". J. Clin. Oncol. 24 (4): 612–8. doi:10.1200/JCO.2005.04.1384. PMID 16380410. Unknown parameter |month= ignored (help)
  2. ↑ Lee J, Park YH, Kim WS; et al. (2005). "Extranodal nasal type NK/T-cell lymphoma: elucidating clinical prognostic factors for risk-based stratification of therapy". Eur. J. Cancer. 41 (10): 1402–8. doi:10.1016/j.ejca.2005.03.010. PMID 15963893. Unknown parameter |month= ignored (help)
  3. ↑ Lee J, Au WY, Park MJ; et al. (2008). "Autologous hematopoietic stem cell transplantation in extranodal natural killer/T cell lymphoma: a multinational, multicenter, matched controlled study". Biol. Blood Marrow Transplant. 14 (12): 1356–64. doi:10.1016/j.bbmt.2008.09.014. PMID 19041057. Unknown parameter |month= ignored (help)
  4. ↑ Stadlmann S, Fend F, Moser P, Obrist P, Greil R, Dirnhofer S (2001). "Epstein-Barr virus-associated extranodal NK/T-cell lymphoma, nasal type of the hypopharynx, in a renal allograft recipient: case report and review of literature". Hum. Pathol. 32 (11): 1264–8. PMID 11727268. Unknown parameter |month= ignored (help)
  5. ↑ Ferenczi K, Summers P, Aubert P; et al. (2008). "A case of CD30+ nasal natural killer/T-cell lymphoma". Am J Dermatopathol. 30 (6): 567–71. doi:10.1097/DAD.0b013e318184bc3f. PMID 19033930. Unknown parameter |month= ignored (help)
  6. ↑ Ian MX, Lan SZ, Cheng ZF, Dan H, Qiong LH (2008). "Suppression of EBNA1 expression inhibits growth of EBV-positive NK/T cell lymphoma cells". Cancer Biol. Ther. 7 (10): 1602–6. PMID 18769118. Unknown parameter |month= ignored (help)
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