Ehrlichiosis: Difference between revisions

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	Ehrlichiosis;
ICD-10	A79.8
ICD-9	082.4
DiseasesDB	31663
MedlinePlus	001381
MeSH	D016873

VisualWikitext

Revision as of 17:07, 6 August 2015

This page is about clinical aspects of the disease. For microbiologic aspects of the causative organism(s), see Ehrlichia.

For patient information on this page, click here

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Raviteja Guddeti, M.B.B.S. [2]

Synonyms and keywords: Sennetsu fever; human granulocytic ehrlichiosis; Anaplasma phagocytophilum; Ehrlichia phagocytophila; human monocytic ehrlichiosis

Overview

Historical Perspective

Classification

Pathophysiology

Causes

Differentiating Ehrlichiosis from other Diseases

Epidemiology and Demographics

Risk Factors

Natural History, Complications and Prognosis

Diagnosis

History and Symptoms | Physical Examination | Laboratory Findings | Other Imaging Findings | Other Diagnostic Studies

Treatment

Medical Therapy | Surgery | Primary Prevention | Secondary Prevention | Future or Investigational Therapies

Case Studies

Case#1

References

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@@ Line 56: / Line 56: @@
-==Treatment==
-* [[Doxycycline]] is the drug of choice.
-* For people allergic to drugs of the [[tetracycline]] class, [[rifampicin]] is an alternative.<ref name="Goddard"/>
-* Early clinical experience suggested that [[chloramphenicol]] may also be effective, however in vitro susceptibility testing revealed [[resistance]].
-===Antimicrobial regimen===
-*1. '''[[Ehrlichiosis|Human Monocytic Ehrlichiosis]] or [[Human Granulocytic Anaplasmosis]] (adult)''' <ref name=CDC centers for the disease control and prevention>{{cite web | title =Ehrlichiosis CDC centers for the disease control and prevention| url= http://www.cdc.gov/ehrlichiosis/symptoms/index.html#treatment }}</ref> <ref>{{cite book | last = Bartlett | first = John | title = Johns Hopkins ABX guide : diagnosis and treatment of infectious diseases | publisher = Jones and Bartlett Learning | location = Burlington, MA | year = 2012 | isbn = 978-1449625580 }}</ref>
-:* Preferred regimen: [[Doxycycline]] 100 mg PO/IV q12h for 7-14 days
-:* Note: Patients should be treated for at least 3 days after the fever subsides and until there is evidence of clinical improvement
-:* Alternative regimen (1): [[Chloramphenicol]] 500mg PO qid
-:* Alternative regimen (2): [[Rifampin]] 600 mg PO/IV qd for 7-10 days
-*2. '''[[Ehrlichiosis|Human Monocytic Ehrlichiosis]] or [[Human Granulocytic Anaplasmosis]] (pediatric)'''
-:*2.1 '''≥ 8 years old'''
-::* Preferred regimen: [[Doxycycline]] 2 mg/kg IV/PO q12h (Maximum, 200 mg/day) for 10 days
-:*2.2 '''< 8 years old without Lyme disease'''
-::* Preferred regimen: [[Doxycycline]] 2 mg/kg IV/PO q12h (Maximum, 200 mg/day) for 4-5 days (or 3 days after resolution of fever)
-:*2.3 '''co-infected with Lyme disease'''
-::* Preferred regimen: [[Doxycycline]], then [[Amoxicillin]] 50 mg/kg in 3 divided doses (Maximum, 500 mg/dose) {{or}} [[Cefuroxime]] 30 mg/kg in 2 divided doses (Maximum, 500 mg/dose) for 14 days
 ==References==

Ehrlichiosis
ICD-10	A79.8
ICD-9	082.4
DiseasesDB	31663
MedlinePlus	001381
MeSH	D016873