Ebastine

Ebastine
	File:Ebastine.svg
Clinical data
Routes of; administration	Oral
ATC code	R06AX22 (WHO) ;
Pharmacokinetic data
Protein binding	Greater than 95%
Metabolism	Hepatic (CYP3A4-mediated), to carebastine
Elimination half-life	15 to 19 hours (carebastine)
Identifiers
	IUPAC name 4-(4-benzhydryloxy-1-piperidyl)-1-; (4-tert-butylphenyl)butan-1-one;
CAS Number	90729-43-4;
PubChem CID	3191;
E number	{{#property:P628}}
ECHA InfoCard	{{#property:P2566}}Lua error in Module:EditAtWikidata at line 36: attempt to index field 'wikibase' (a nil value).
Chemical and physical data
Formula	C32H39NO2
Molar mass	469.658 g/mol

Ebastine (trade names Kestine, Evastin, Ebastel, Aleva) is a non-sedating H₁ antihistamine.

It does not penetrate the blood-brain barrier and thus allows an effective block of the H₁ receptor in peripheral tissue without a central side effect, i.e not causing sedation or drowsiness.

External links

"KESTINE® Package Insert". South African Electronic Package Inserts. October 24, 1997. Retrieved 2007-04-01.

Template:Pharma-stub th:อีบาสทีน Template:WikiDoc Sources

v t e Antihistamines (R06)
Aminoalkyl ethers	Bromazine/Bromodiphenhydramine • Carbinoxamine • Clemastine • Chlorphenoxamine • Diphenylpyraline • Diphenhydramine • Doxylamine • Orphenadrine • Phenyltoloxamine
Substituted alkylamines	Brompheniramine • Chlorphenamine • Dexbrompheniramine • Dexchlorpheniramine • Dimetindene • Pheniramine • Talastine
Substituted ethylenediamines	Chloropyramine • Histapyrrodine • Mepyramine • Methapyrilene • Tripelennamine (Pyribenzamine)
Phenothiazine derivatives	Alimemazine • Hydroxyethylpromethazine • Isothipendyl • Mequitazine • Methdilazine • Oxomemazine • Promethazine
Piperazine derivatives	Buclizine • Cetirizine • Chlorcyclizine • Cinnarizine • Cyclizine • Hydroxyzine • Levocetirizine • Meclizine • Niaprazine • Oxatomide
Others for systemic use	Antazoline • Azatadine • Bamipine • Cyproheptadine • Deptropine • Dimebon • Ebastine • Epinastine • Ketotifen • Mebhydrolin • Mizolastine • Phenindamine • Pimethixene • Pyrrobutamine • Rupatadine • Triprolidine • selective (Acrivastine • Astemizole • Azelastine • Desloratadine • Fexofenadine • Loratadine • Terfenadine)
For topical use	Bamipine • Chloropyramine • Chlorphenoxamine • Clemastine • Dimetindene • Diphenhydramine • Isothipendyl • Mepyramine • Promethazine • Thenalidine
Antiallergic agents excluding corticosteroids	Antazoline • Azelastine
Other antiallergics	Emedastine • Epinastine • Ketotifen • Montelukast • Olopatadine

Clinical data
File:Ebastine.svg
Routes of administration	Oral
ATC code	R06AX22 (WHO)
Pharmacokinetic data
Protein binding	Greater than 95%
Metabolism	Hepatic (CYP3A4-mediated), to carebastine
Elimination half-life	15 to 19 hours (carebastine)
Identifiers
IUPAC name 4-(4-benzhydryloxy-1-piperidyl)-1- (4-tert-butylphenyl)butan-1-one
CAS Number	90729-43-4
PubChem CID	3191
E number	{{#property:P628}}
ECHA InfoCard	{{#property:P2566}}Lua error in Module:EditAtWikidata at line 36: attempt to index field 'wikibase' (a nil value).
Chemical and physical data
Formula	C₃₂H₃₉NO₂
Molar mass	469.658 g/mol

Ebastine

External links

Navigation menu