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{{Donovanosis}}
{{Donovanosis}}
{{CMG}} {{AE}} {{KD}}
{{CMG}} {{AE}} {{KD}}; {{NRM}}
 
==Overview==
 
==History and Symptoms==
==History and Symptoms==
Symptoms can occur 1 to 12 weeks after coming in contact with the bacteria that cause the disease.
Patients who present to a physician will typically report sexual contact from 3 to 40 days prior to symptom onset.<ref name="Richens">{{cite journal| author=Richens J| title=The diagnosis and treatment of donovanosis (granuloma inguinale). | journal=Genitourin Med | year= 1991 | volume= 67 | issue= 6 | pages= 441-52 | pmid=1774048 | doi= | pmc=PMC1194766 | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=1774048  }} </ref>


* About half of infected men and women have sores in the anal area.
Local symptoms include:<ref name="VelhoSouza2008">{{cite journal|last1=Velho|first1=Paulo Eduardo Neves Ferreira|last2=Souza|first2=Elemir Macedo de|last3=Belda Junior|first3=Walter|title=Donovanosis|journal=Brazilian Journal of Infectious Diseases|volume=12|issue=6|year=2008|issn=1413-8670|doi=10.1590/S1413-86702008000600015}}</ref>
* Small, beefy-red bumps appear on the genitals or around the [[anus]].
*Painless [[papule]](s)
* The skin gradually wears away, and the bumps turn into raised, beefy-red, velvety nodules called granulation tissue. They are usually painless, but they bleed easily if injured.
*Painless [[Ulcer]](s) of [[granulomatous]] tissue
* The disease slowly spreads and destroys genital tissue.
*Ulcer bleeding
* [[Tissue]] damage may spread to the area where the legs meet the torso. This area is called the inguinal folds.
*[[Periadenitis]]
* The genitals and the skin around them lose skin color.
*"Psuedobuboes": firm nodules or [[abscesses]]
* In its early stages, it may be hard to tell the difference between donovanosis and [[chancroid]].
*Absent [[lymphadenopathy]]
* In the later stages, donovanosis may look like advanced genital cancers, [[lymphogranuloma venereum]], and anogenital cutaneous [[amebiasis]].
 
If the disease disseminates as a result of chronic ulcers, systemic symptoms may develop inlcuding:<ref name="VelhoSouza2008"></ref>
*[[Fever]]
*[[Malaise]]
*[[Anemia]]
*[[Toxemia]]
*Night sweats
*Weight loss


==References==
==References==
<references/>
{{reflist|2}}
 
 
[[Category:Sexually transmitted infections]]
[[Category:Sexually transmitted infections]]
[[Category:Bacterial diseases]]
[[Category:Bacterial diseases]]

Revision as of 18:25, 2 March 2016

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Kalsang Dolma, M.B.B.S.[2]; Nate Michalak, B.A.

Overview

History and Symptoms

Patients who present to a physician will typically report sexual contact from 3 to 40 days prior to symptom onset.[1]

Local symptoms include:[2]

If the disease disseminates as a result of chronic ulcers, systemic symptoms may develop inlcuding:[2]

References

  1. Richens J (1991). "The diagnosis and treatment of donovanosis (granuloma inguinale)". Genitourin Med. 67 (6): 441–52. PMC 1194766. PMID 1774048.
  2. 2.0 2.1 Velho, Paulo Eduardo Neves Ferreira; Souza, Elemir Macedo de; Belda Junior, Walter (2008). "Donovanosis". Brazilian Journal of Infectious Diseases. 12 (6). doi:10.1590/S1413-86702008000600015. ISSN 1413-8670.

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