Donovanosis epidemiology and demographics

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Kalsang Dolma, M.B.B.S.[2]; Nate Michalak, B.A.

Overview

A true incidence of donovanosis is difficult to determine due to limited knowledge of the disease, limited diagnostic tests, infrequency of disease compared to other sexually transmitted diseases, and occurrence of the disease in areas with limited resources. Most infections occur in people who's ages range from 20 to 40 years. Sex and race are not a predilection for acquiring the disease. Donovanosis is rare in the United States and other developed countries. Donovanosis is endemic in tropical and developing areas, including India, Papua New Guinea, the Caribbean, central Australia, and southern Africa.

Epidemiology and Demographics

Incidence

  • A true incidence of donovanosis is difficult to determine due to limited knowledge of the disease, limited diagnostic tests, infrequency of disease compared to other sexually transmitted diseases, and occurrence of the disease in areas with limited resources.

Age

  • Most infections occur in people ages 20-40. The disease is rarely seen in children or the elderly.

Gender

  • Although more males present with the disease, sex does not appear to be a risk factor.

Race

  • Donovanosis is more common among African-Americans but this is most likely due to socioeconomic disparities.[1]

Developed Countries

  • Donovanosis is rare in the United States and other developed countries.[2][1]

Developing Countries

  • Donovanosis is endemic in tropical and developing areas, including India, Papua New Guinea, the Caribbean, central Australia, and southern Africa.[3][2]
  • The largest epidemic occurred between 1922 and 1952 in Papua New Guinea where 10,000 cases were identified in a population of 15,000.
  • Between 1993 and 1997 in southern India, 14% of genital ulcer cases were identified as donovanosis.
  • 3,153 cases of donovanosis were recorded in Durban, South Africa during the late 1980s through late 1990s.[4]

References

  1. 1.0 1.1 Velho, Paulo Eduardo Neves Ferreira; Souza, Elemir Macedo de; Belda Junior, Walter (2008). "Donovanosis". Brazilian Journal of Infectious Diseases. 12 (6). doi:10.1590/S1413-86702008000600015. ISSN 1413-8670.
  2. 2.0 2.1 2015 Sexually Transmitted Diseases Treatment Guidelines. Centers for Disease Control and Prevention (June 4, 2015). http://www.cdc.gov/std/tg2015/donovanosis.htm Accessed February 29, 2016.
  3. Richens J (1991). "The diagnosis and treatment of donovanosis (granuloma inguinale)". Genitourin Med. 67 (6): 441–52. PMC 1194766. PMID 1774048.
  4. O'Farrell N (2002). "Donovanosis". Sex Transm Infect. 78 (6): 452–7. PMC 1758360. PMID 12473810.


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