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==Overview==
==Overview==
Patients develop the following local symptoms, typically 3 to 40 days after sexual contact: painless [[papules]], painless [[ulcers]] of [[granulomatous]] tissue that spread and bleed easily, periadenitis, "pseudobuboes", and absent [[lymphadenopathy]]. If the disease disseminates as a result of chronic ulcers, systemic symptoms may develop including: [[fever]], [[malaise]], [[anemia]], night sweats, weight loss and [[toxemia]].


==History and Symptoms==
==History and Symptoms==
Patients who present to a physician will typically report sexual contact from 3 to 40 days prior to symptom onset.<ref name="Richens">{{cite journal| author=Richens J| title=The diagnosis and treatment of donovanosis (granuloma inguinale). | journal=Genitourin Med | year= 1991 | volume= 67 | issue= 6 | pages= 441-52 | pmid=1774048 | doi= | pmc=PMC1194766 | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=1774048  }} </ref>
Patients who present to a physician will typically report sexual contact from 3 to 40 days prior to symptom onset.<ref name="Richens">{{cite journal| author=Richens J| title=The diagnosis and treatment of donovanosis (granuloma inguinale). | journal=Genitourin Med | year= 1991 | volume= 67 | issue= 6 | pages= 441-52 | pmid=1774048 | doi= | pmc=PMC1194766 | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=1774048  }} </ref>


Local symptoms include:<ref name="VelhoSouza2008">{{cite journal|last1=Velho|first1=Paulo Eduardo Neves Ferreira|last2=Souza|first2=Elemir Macedo de|last3=Belda Junior|first3=Walter|title=Donovanosis|journal=Brazilian Journal of Infectious Diseases|volume=12|issue=6|year=2008|issn=1413-8670|doi=10.1590/S1413-86702008000600015}}</ref>
Local symptoms include:<ref name="VelhoSouza2008">{{cite journal|last1=Velho|first1=Paulo Eduardo Neves Ferreira|last2=Souza|first2=Elemir Macedo de|last3=Belda Junior|first3=Walter|title=Donovanosis|journal=Brazilian Journal of Infectious Diseases|volume=12|issue=6|year=2008|issn=1413-8670|doi=10.1590/S1413-86702008000600015}}</ref><ref>Donovanosis (granuloma inguinale). MedlinePlus (September 01, 2013). https://www.nlm.nih.gov/medlineplus/ency/article/000636.htm Accessed March 02, 2016.</ref>
*Painless [[papule]](s)
*Painless [[papule]](s)
*Painless [[Ulcer]](s) of [[granulomatous]] tissue
*Painless [[Ulcer]](s) of [[granulomatous]] tissue
*Ulcers spreading and wearing away skin
*Ulcer bleeding
*Ulcer bleeding
*[[Periadenitis]]
*Periadenitis
*"Psuedobuboes": firm nodules or [[abscesses]]
*"Psuedobuboes": firm nodules or [[abscesses]]
*Absent [[lymphadenopathy]]
*Absent [[lymphadenopathy]]


If the disease disseminates as a result of chronic ulcers, systemic symptoms may develop inlcuding:<ref name="VelhoSouza2008"></ref>
If the disease disseminates as a result of chronic ulcers, systemic symptoms may develop including:<ref name="VelhoSouza2008"></ref>
*[[Fever]]
*[[Fever]]
*[[Malaise]]
*[[Malaise]]
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[[Category:Sexually transmitted infections]]
[[Category:Sexually transmitted infections]]
[[Category:Bacterial diseases]]
[[Category:Bacterial diseases]]
[[Category:Infectious disease]]
 
[[Category:Disease]]
[[Category:Disease]]
[[Category:Needs overview]]
 
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Latest revision as of 17:36, 18 September 2017

Donovanosis Microchapters

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Overview

Historical Perspective

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Differentiating Donovanosis from other Diseases

Epidemiology and Demographics

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Natural History, Complications and Prognosis

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Kalsang Dolma, M.B.B.S.[2]; Nate Michalak, B.A.

Overview

Patients develop the following local symptoms, typically 3 to 40 days after sexual contact: painless papules, painless ulcers of granulomatous tissue that spread and bleed easily, periadenitis, "pseudobuboes", and absent lymphadenopathy. If the disease disseminates as a result of chronic ulcers, systemic symptoms may develop including: fever, malaise, anemia, night sweats, weight loss and toxemia.

History and Symptoms

Patients who present to a physician will typically report sexual contact from 3 to 40 days prior to symptom onset.[1]

Local symptoms include:[2][3]

If the disease disseminates as a result of chronic ulcers, systemic symptoms may develop including:[2]

References

  1. Richens J (1991). "The diagnosis and treatment of donovanosis (granuloma inguinale)". Genitourin Med. 67 (6): 441–52. PMC 1194766. PMID 1774048.
  2. 2.0 2.1 Velho, Paulo Eduardo Neves Ferreira; Souza, Elemir Macedo de; Belda Junior, Walter (2008). "Donovanosis". Brazilian Journal of Infectious Diseases. 12 (6). doi:10.1590/S1413-86702008000600015. ISSN 1413-8670.
  3. Donovanosis (granuloma inguinale). MedlinePlus (September 01, 2013). https://www.nlm.nih.gov/medlineplus/ency/article/000636.htm Accessed March 02, 2016.


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