Diverticulitis risk factors
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Ahmed Elsaiey, MBBCH [2]
Overview
Risk factors in the development of diverticulitis include advanced age, chronic constipation, connective tissue diseases (such as Marfan syndrome or Ehlers Danlos syndrome), low dietary fiber intake, high intake of fat and red meat, and obesity. There are risk factors for the disease recurrence as well. These factors include multiple diverticula, intraperitoneal abscess, family history of diverticulitis, and great portion of the colon involved in the disease.
Risk Factors
Risk factors of diverticulosis and diverticulitis
Risk factors in the development of diverticulosis and diverticulitis include the following:[1]
- Advanced age
- Chronic constipation
- Smoking
- Connective tissue disorders
- Low fiber diet
- The role of fiber in the development of diverticulitis remains unclear. Although classically low fiber diet has been associated with development of diverticulosis, results from newer studies are conflicting.[2] However, dietary fiber and a vegetarian diet may reduce the incidence of symptomatic diverticular disease by decreasing intestinal inflammation and altering the intestinal microbiota.[3][4]
- High fiber and red meat diet
- The risk of diverticulosis may be significantly increased with diets that are high in total fat or red meat compared with fat and red meat-rich diets.[3]
- Obesity
Risk factors of diverticulitis recurrence
Recurrence of diverticulitis has been reported to occur in 20% of patients with previous episodes of diverticulitis.[5]Risk factors for diverticulitis include the following:[6][7]
- Diverticulosis itself is a risk factor for recurrence
- Multiple diverticula
- Intraperitoneal diverticulitis
- Presence of retroperitoneal abscesses increase the risk of disease diverticulitis.
- Patients with family history of diverticulitis.
- Patients who have a big portion of the infected colon.
- Patients with C-reactive protein more than 240 mg are more susceptible for diverticulitis recurrence.[8]
References
- ↑ Strate LL, Liu YL, Aldoori WH, Syngal S, Giovannucci EL (2009). "Obesity increases the risks of diverticulitis and diverticular bleeding". Gastroenterology. 136 (1): 115–122.e1. doi:10.1053/j.gastro.2008.09.025. PMC 2643271. PMID 18996378.
- ↑ Peery AF, Sandler RS, Ahnen DJ, Galanko JA, Holm AN, Shaukat A, Mott LA, Barry EL, Fried DA, Baron JA (2013). "Constipation and a low-fiber diet are not associated with diverticulosis". Clin. Gastroenterol. Hepatol. 11 (12): 1622–7. doi:10.1016/j.cgh.2013.06.033. PMC 3840096. PMID 23891924.
- ↑ 3.0 3.1 Aldoori WH, Giovannucci EL, Rimm EB, Wing AL, Trichopoulos DV, Willett WC (1994). "A prospective study of diet and the risk of symptomatic diverticular disease in men". Am. J. Clin. Nutr. 60 (5): 757–64. PMID 7942584.
- ↑ Painter NS, Burkitt DP (1971). "Diverticular disease of the colon: a deficiency disease of Western civilization". Br Med J. 2 (5759): 450–4. PMC 1796198. PMID 4930390.
- ↑ Peery AF (2016). "Recent Advances in Diverticular Disease". Curr Gastroenterol Rep. 18 (7): 37. doi:10.1007/s11894-016-0513-1. PMID 27241190.
- ↑ Park HC, Kim BS, Lee K, Kim MJ, Lee BH (2014). "Risk factors for recurrence of right colonic uncomplicated diverticulitis after first attack". Int J Colorectal Dis. 29 (10): 1217–22. doi:10.1007/s00384-014-1941-8. PMID 24980689.
- ↑ Hall JF, Roberts PL, Ricciardi R, Read T, Scheirey C, Wald C; et al. (2011). "Long-term follow-up after an initial episode of diverticulitis: what are the predictors of recurrence?". Dis Colon Rectum. 54 (3): 283–8. doi:10.1007/DCR.0b013e3182028576. PMID 21304297.
- ↑ Buchs NC, Mortensen NJ, Ris F, Morel P, Gervaz P (2015). "Natural history of uncomplicated sigmoid diverticulitis". World J Gastrointest Surg. 7 (11): 313–8. doi:10.4240/wjgs.v7.i11.313. PMC 4663385. PMID 26649154.