Diverticulitis laboratory findings: Difference between revisions
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==Overview== | ==Overview== | ||
Diagnosis of diverticulitis starts by recording patient history and performing a [[physical examination]]. Laboratory tests are important in excluding other causes of [[abdominal pain]] and any other [[Gastrointestinal diseases|gastrointestinal disease]]. These laboratory tests include complete blood count ([[Complete blood count|CBC]]), C-reactive protein ([[CRP]]), [[urinalysis]], and [[liver function tests]]. Imaging studies including [[Computed tomography|CT scan]] and [[colonoscopy]] are also important measures in diagnosing diverticulitis.<ref name="pmid16741596">{{cite journal| author=Rafferty J, Shellito P, Hyman NH, Buie WD, Standards Committee of American Society of Colon and Rectal Surgeons| title=Practice parameters for sigmoid diverticulitis. | journal=Dis Colon Rectum | year= 2006 | volume= 49 | issue= 7 | pages= 939-44 | pmid=16741596 | doi=10.1007/s10350-006-0578-2 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=16741596 }} </ref><ref name="pmid20645093">{{cite journal| author=Käser SA, Fankhauser G, Glauser PM, Toia D, Maurer CA| title=Diagnostic value of inflammation markers in predicting perforation in acute sigmoid diverticulitis. | journal=World J Surg | year= 2010 | volume= 34 | issue= 11 | pages= 2717-22 | pmid=20645093 | doi=10.1007/s00268-010-0726-7 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=20645093 }} </ref> | |||
==Laboratory Findings== | ==Laboratory Findings== | ||
The initial diagnostic measures for diverticulitis are taking a proper [[History & Symptoms|history]], doing a [[physical exam]], and performing | The initial diagnostic measures for diverticulitis are taking a proper [[History & Symptoms|history]], doing a [[physical exam]], and performing laboratory tests. Laboratory tests are initially necessary to exclude other [[gastrointestinal diseases]] and confirm diverticulitis. These lab tests include the following: | ||
*[[CRP]] | *C-reactive protein ([[CRP]]) - elevated due to [[inflammation]] | ||
*[[CBC]] | *Complete blood count ([[CBC]])- [[CBC]] may show [[leukocytosis]]. A normal [[white blood cell]] count does not exclude diverticulitis, as most patients suffering from diverticulitis have normal [[blood]] [[cell]] counts. | ||
*[[Urinalysis]]: [[Urinalysis]] is performed especially in cases complicated by [[fistula]] and may show the following findings:<ref name="pmid13903556">{{cite journal| author=HAFNER CD, PONKA JL, BRUSH BE| title=Genitourinary manifestations of diverticulitis of the colon. A study of 500 cases. | journal=JAMA | year= 1962 | volume= 179 | issue= | pages= 76-8 | pmid=13903556 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=13903556 }} </ref> | *[[Urinalysis]]: [[Urinalysis]] is performed especially in cases complicated by [[fistula]] and may show the following findings:<ref name="pmid13903556">{{cite journal| author=HAFNER CD, PONKA JL, BRUSH BE| title=Genitourinary manifestations of diverticulitis of the colon. A study of 500 cases. | journal=JAMA | year= 1962 | volume= 179 | issue= | pages= 76-8 | pmid=13903556 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=13903556 }} </ref> | ||
**[[Pyuria]] | **[[Pyuria]]- In the case of [[urinary tract infection]] | ||
**[[Hematuria]] | **[[Hematuria]]- In the case of [[nephrolithiasis]] | ||
*[[Liver function]] tests | *[[Liver function]] tests- [[Amylase]] and [[lipase]] levels should be checked to exclude other diseases that cause [[abdominal pain]]. | ||
==References== | ==References== | ||
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{{WH}} | {{WH}} | ||
{{WS}}[[Category:Emergency medicine]] | {{WS}} | ||
[[Category:Emergency medicine]] | |||
[[Category:Disease]] | [[Category:Disease]] | ||
[[Category:Primary care]] | [[Category:Primary care]] | ||
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Ahmed Elsaiey, MBBCH [2]
Overview
Diagnosis of diverticulitis starts by recording patient history and performing a physical examination. Laboratory tests are important in excluding other causes of abdominal pain and any other gastrointestinal disease. These laboratory tests include complete blood count (CBC), C-reactive protein (CRP), urinalysis, and liver function tests. Imaging studies including CT scan and colonoscopy are also important measures in diagnosing diverticulitis.[1][2]
Laboratory Findings
The initial diagnostic measures for diverticulitis are taking a proper history, doing a physical exam, and performing laboratory tests. Laboratory tests are initially necessary to exclude other gastrointestinal diseases and confirm diverticulitis. These lab tests include the following:
- C-reactive protein (CRP) - elevated due to inflammation
- Complete blood count (CBC)- CBC may show leukocytosis. A normal white blood cell count does not exclude diverticulitis, as most patients suffering from diverticulitis have normal blood cell counts.
- Urinalysis: Urinalysis is performed especially in cases complicated by fistula and may show the following findings:[3]
- Pyuria- In the case of urinary tract infection
- Hematuria- In the case of nephrolithiasis
- Liver function tests- Amylase and lipase levels should be checked to exclude other diseases that cause abdominal pain.
References
- ↑ Rafferty J, Shellito P, Hyman NH, Buie WD, Standards Committee of American Society of Colon and Rectal Surgeons (2006). "Practice parameters for sigmoid diverticulitis". Dis Colon Rectum. 49 (7): 939–44. doi:10.1007/s10350-006-0578-2. PMID 16741596.
- ↑ Käser SA, Fankhauser G, Glauser PM, Toia D, Maurer CA (2010). "Diagnostic value of inflammation markers in predicting perforation in acute sigmoid diverticulitis". World J Surg. 34 (11): 2717–22. doi:10.1007/s00268-010-0726-7. PMID 20645093.
- ↑ HAFNER CD, PONKA JL, BRUSH BE (1962). "Genitourinary manifestations of diverticulitis of the colon. A study of 500 cases". JAMA. 179: 76–8. PMID 13903556.