Creutzfeldt-Jakob disease other imaging findings: Difference between revisions

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{{‪Creutzfeldt-Jakob disease‬}}
{{‪Creutzfeldt-Jakob disease‬}}
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==Overview==
==Overview==
CT scan mainly helps in excluding an alternative diagnosis and is generally normal in CJD.
[[Positron emission tomography|PET scan]] is generally normal in Creutzfeldt-Jakob disease and may be helpful in ruling out other diseases. On [[Positron emission tomography|PET scan]], abnormalities in thalamic regions may be present.
==CT Scan==
Rapidly progressive ventricular enlargement and cortical atrophy have been shown to be present in CJD on serial CT scans.<ref name="Hayashi-1992">{{Cite journal  | last1 = Hayashi | first1 = R. | last2 = Hanyu | first2 = N. | last3 = Kuwabara | first3 = T. | last4 = Moriyama | first4 = S. | title = Serial computed tomographic and electroencephalographic studies in Creutzfeldt-Jakob disease. | journal = Acta Neurol Scand | volume = 85 | issue = 3 | pages = 161-5 | month = Mar | year = 1992 | doi =  | PMID = 1574996 }}</ref>


==PET Scan==
==PET Scan==
Abnormalities in thalamic region have been shown to be present on PET scan in thalamic MM2 subtype of CJD, however, its significance in diagnosis has not been extablished yet.<ref name="Hamaguchi-2005">{{Cite journal  | last1 = Hamaguchi | first1 = T. | last2 = Kitamoto | first2 = T. | last3 = Sato | first3 = T. | last4 = Mizusawa | first4 = H. | last5 = Nakamura | first5 = Y. | last6 = Noguchi | first6 = M. | last7 = Furukawa | first7 = Y. | last8 = Ishida | first8 = C. | last9 = Kuji | first9 = I. | title = Clinical diagnosis of MM2-type sporadic Creutzfeldt-Jakob disease. | journal = Neurology | volume = 64 | issue = 4 | pages = 643-8 | month = Feb | year = 2005 | doi = 10.1212/01.WNL.0000151847.57956.FA | PMID = 15728285 }}</ref><ref name="Macfarlane-2007">{{Cite journal  | last1 = Macfarlane | first1 = RG. | last2 = Wroe | first2 = SJ. | last3 = Collinge | first3 = J. | last4 = Yousry | first4 = TA. | last5 = Jäger | first5 = HR. | title = Neuroimaging findings in human prion disease. | journal = J Neurol Neurosurg Psychiatry | volume = 78 | issue = 7 | pages = 664-70 | month = Jul | year = 2007 | doi = 10.1136/jnnp.2006.094821 | PMID = 17135459 }}</ref>
* [[Positron emission tomography|PET scan]] is generally normal in Creutzfeldt-Jakob disease and may be helpful in ruling out other diseases.<ref name="Hamaguchi-2005" /><ref name="Macfarlane-2007" />


*On [[Positron emission tomography|PET scan]], abnormalities in thalamic regions may be present.<ref name="Hamaguchi-2005">{{Cite journal  | last1 = Hamaguchi | first1 = T. | last2 = Kitamoto | first2 = T. | last3 = Sato | first3 = T. | last4 = Mizusawa | first4 = H. | last5 = Nakamura | first5 = Y. | last6 = Noguchi | first6 = M. | last7 = Furukawa | first7 = Y. | last8 = Ishida | first8 = C. | last9 = Kuji | first9 = I. | title = Clinical diagnosis of MM2-type sporadic Creutzfeldt-Jakob disease. | journal = Neurology | volume = 64 | issue = 4 | pages = 643-8 | month = Feb | year = 2005 | doi = 10.1212/01.WNL.0000151847.57956.FA | PMID = 15728285 }}</ref><ref name="Macfarlane-2007">{{Cite journal  | last1 = Macfarlane | first1 = RG. | last2 = Wroe | first2 = SJ. | last3 = Collinge | first3 = J. | last4 = Yousry | first4 = TA. | last5 = Jäger | first5 = HR. | title = Neuroimaging findings in human prion disease. | journal = J Neurol Neurosurg Psychiatry | volume = 78 | issue = 7 | pages = 664-70 | month = Jul | year = 2007 | doi = 10.1136/jnnp.2006.094821 | PMID = 17135459 }}</ref>


==References==
==References==
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Latest revision as of 05:05, 30 October 2018

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

PET scan is generally normal in Creutzfeldt-Jakob disease and may be helpful in ruling out other diseases. On PET scan, abnormalities in thalamic regions may be present.

PET Scan

  • PET scan is generally normal in Creutzfeldt-Jakob disease and may be helpful in ruling out other diseases.[1][2]

References

  1. 1.0 1.1 Hamaguchi, T.; Kitamoto, T.; Sato, T.; Mizusawa, H.; Nakamura, Y.; Noguchi, M.; Furukawa, Y.; Ishida, C.; Kuji, I. (2005). "Clinical diagnosis of MM2-type sporadic Creutzfeldt-Jakob disease". Neurology. 64 (4): 643–8. doi:10.1212/01.WNL.0000151847.57956.FA. PMID 15728285. Unknown parameter |month= ignored (help)
  2. 2.0 2.1 Macfarlane, RG.; Wroe, SJ.; Collinge, J.; Yousry, TA.; Jäger, HR. (2007). "Neuroimaging findings in human prion disease". J Neurol Neurosurg Psychiatry. 78 (7): 664–70. doi:10.1136/jnnp.2006.094821. PMID 17135459. Unknown parameter |month= ignored (help)


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