Creutzfeldt-Jakob disease physical examination
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Mohamadmostafa Jahansouz M.D.[2]
Overview
Physical Examination
Appearance of the Patient
- Patients with Creutzfeldt-Jakob disease usually appear confused.
Vital Signs
- Vital Signs of patients with Creutzfeldt-Jakob disease are usually normal.
Skin
- Skin examination of patients with Creutzfeldt-Jakob disease is usually normal.
HEENT
- HEENT examination of patients with Creutzfeldt-Jakob disease is usually normal.
Neck
- Neck examination of patients with Creutzfeldt-Jakob disease is usually normal.
Lungs
- Pulmonary examination of patients with Creutzfeldt-Jakob disease is usually normal.
Heart
- Cardiovascular examination of patients with Creutzfeldt-Jakob disease is usually normal.
Abdomen
- Abdominal examination of patients with Creutzfeldt-Jakob disease is usually normal.
Back
- Back examination of patients with Creutzfeldt-Jakob disease is usually normal.
Genitourinary
- Genitourinary examination of patients with Creutzfeldt-Jakob disease is usually normal.
Neuromuscular
Physical examination of patients with Creutzfeldt-Jakob disease is usually remarkable for:[1][2][3][4][5]
- Speech impairment
- Myoclonus
- Ataxia
- Gait disturbances
- Rigid posture
- Dysarthria
- Myoclonus
- Visual changes leading to cortical blindness
- Akinetic mutism in the last stages of the disease
- Chorea
- Peripheral neuropathy
- Altered mental status
Myoclonus is the most common sign in patients Creutzfeldt-Jakob disease.
Patient is usually disoriented to persons, place, and time.
Extremities
- Extremities examination of patients with Creutzfeldt-Jakob disease is usually normal.
References
- ↑ Head MW, Ironside JW (June 2012). "Review: Creutzfeldt-Jakob disease: prion protein type, disease phenotype and agent strain". Neuropathol. Appl. Neurobiol. 38 (4): 296–310. doi:10.1111/j.1365-2990.2012.01265.x. PMID 22394291.
- ↑ Argelander H (May 1968). "[The psychoanalytic dialogue]". Psyche (Stuttg) (in German). 22 (5): 325–39. PMID 5710312.
- ↑ Sikorska B, Knight R, Ironside JW, Liberski PP (2012). "Creutzfeldt-Jakob disease". Adv. Exp. Med. Biol. 724: 76–90. doi:10.1007/978-1-4614-0653-2_6. PMID 22411235.
- ↑ Sitammagari KK, Masood W. PMID 29939637. Missing or empty
|title=(help) - ↑ Helton AS, Snodgrass FG (September 1987). "Battering during pregnancy: intervention strategies". Birth. 14 (3): 142–7. PMID 3689509.