Creutzfeldt-Jakob disease natural history, complications and prognosis: Difference between revisions

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Revision as of 20:30, 17 March 2016

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Once symptoms develop, Creutzfeldt-Jakob disease is rapidly progressive and almost always fatal. Early symptoms are often non-specific. Patients' relatives usually report rapidly progressive dementia, personality changes, and sleep disorders. The majority of patients (85% of patients) die within 1 year of symptom-onset. Common complications of Creutzfeldt-Jakob disease include overwhelming infections, congestive heart failure, or respiratory failure.

Natural History

Once symptoms develop, Creutzfeldt-Jakob disease is rapidly progressive and almost always fatal.
Early symptoms are often non-specific. Patients' relatives usually report rapidly progressive dementia, personality changes, and sleep disorders.
The majority of patients (85% of patients) die within 1 year of symptom-onset, often due to complicatioons succh as overwhelming infections, congestive heart failure, or respiratory failure.^[1]

Complications

Complications of Creutzfeldt-Jakob disease include the following:

Prognosis

The prognosis of Creutzfeldt-Jakob disease is very poor.
Patients usually die within 6 to 12 months of symptom-onset.
A few reports described individuals surviving beyond than 1 or 2 years after diagnosis.

References

↑ "http://www.cdc.gov/ncidod/dvrd/cjd/index.htm". Retrieved 17 February 2014. External link in |title= (help)

Template:WikiDoc Sources

[www.cdc.gov-1] "http://www.cdc.gov/ncidod/dvrd/cjd/index.htm". Retrieved 17 February 2014. External link in |title= (help)

[1]

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-Please help WikiDoc by adding more content here.  It's easy!  Click  [[Help:How_to_Edit_a_Page|here]]  to learn about editing.
 {{CMG}}
 ==Overview==
-Creutzfeldt Jakob disease is rapidly progressive and always fatal.  Infection with this disease leads to death usually within 1 year of onset of illness.<ref name="www.cdc.gov">{{Cite web  | last =  | first =  | title = http://www.cdc.gov/ncidod/dvrd/cjd/index.htm | url = http://www.cdc.gov/ncidod/dvrd/cjd/index.htm | publisher =  | date =  | accessdate = 17 February 2014 }}</ref>
+Once symptoms develop, Creutzfeldt-Jakob disease is rapidly progressive and almost always fatal. Early symptoms are often non-specific. Patients' relatives usually report rapidly progressive dementia, personality changes, and sleep disorders. The majority of patients (85% of patients) die within 1 year of symptom-onset. Common complications of Creutzfeldt-Jakob disease include overwhelming infections, congestive heart failure, or respiratory failure.
+==Natural History==
+*Once symptoms develop, Creutzfeldt-Jakob disease is rapidly progressive and almost always fatal.
+*Early symptoms are often non-specific. Patients' relatives usually report rapidly progressive dementia, personality changes, and sleep disorders.
+*The majority of patients (85% of patients) die within 1 year of symptom-onset, often due to complicatioons succh as overwhelming infections, congestive heart failure, or respiratory failure.<ref name="www.cdc.gov">{{Cite web  | last =  | first =  | title = http://www.cdc.gov/ncidod/dvrd/cjd/index.htm | url = http://www.cdc.gov/ncidod/dvrd/cjd/index.htm | publisher =  | date =  | accessdate = 17 February 2014 }}</ref>
 ==Complications==
+Complications of Creutzfeldt-Jakob disease include the following:
 * [[Infection]]
-* [[Congestive heart failure (patient information)|Heart failure]]
+* [[Heart failure]]
 * [[Respiratory failure]]
-* Loss of ability to function or care for oneself
-* Loss of ability to interact with others
 * Death
 ==Prognosis==
-* The outcome is usually very poor.  Within 6 months or less of the onset of symptoms, the person will become incapable of self-care.
+*The prognosis of Creutzfeldt-Jakob disease is very poor.
+*Patients usually die within 6 to 12 months of symptom-onset.
-* The disorder is fatal in a short time, usually within 8 months, but a few people survive as long as 1 or 2 years after diagnosis.
+* A few reports described individuals surviving beyond than 1 or 2 years after diagnosis.
-* The cause of death is usually [[infection]], [[congestive heart failure (patient information)|heart failure]], or [[respiratory failure]].
 ==References==
 {{Reflist|2}}
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-[[Category:Needs content]]
 [[Category:Infectious disease]]
 [[Category:Neurology]]
 [[Category:Disease]]
 [[Category:Transmissible spongiform encephalopathies]]
-[[Category:Needs overview]]