Cowden syndrome natural history, complications and prognosis: Difference between revisions
| Line 12: | Line 12: | ||
===Complications=== | ===Complications=== | ||
*Common [[complications]] of [[cowden syndrome]] include: | *Common [[complications]] of [[cowden syndrome]] include:<ref name="pmid9715274">{{cite journal |vauthors=FitzGerald MG, Marsh DJ, Wahrer D, Bell D, Caron S, Shannon KE, Ishioka C, Isselbacher KJ, Garber JE, Eng C, Haber DA |title=Germline mutations in PTEN are an infrequent cause of genetic predisposition to breast cancer |journal=Oncogene |volume=17 |issue=6 |pages=727–31 |date=August 1998 |pmid=9715274 |doi=10.1038/sj.onc.1201984 |url=}}</ref> | ||
**[[Breast cancer]] | **[[Breast cancer]] | ||
**[[Colon cancer]] | **[[Colon cancer]] | ||
Revision as of 21:49, 4 March 2019
|
Cowden syndrome Microchapters |
|
Diagnosis |
|---|
|
Treatment |
|
Case Studies |
|
Cowden syndrome natural history, complications and prognosis On the Web |
|
American Roentgen Ray Society Images of Cowden syndrome natural history, complications and prognosis |
|
FDA on Cowden syndrome natural history, complications and prognosis |
|
CDC on Cowden syndrome natural history, complications and prognosis |
|
Cowden syndrome natural history, complications and prognosis in the news |
|
Blogs on Cowden syndrome natural history, complications and prognosis |
|
Risk calculators and risk factors for Cowden syndrome natural history, complications and prognosis |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Vamsikrishna Gunnam M.B.B.S [2]
Overview
Cowden syndrome follows an autosomal dominant pattern of inheritance. If left untreated, patients with cowden syndrome may prone to develop manu cancers.Common complications of cowden syndrome include breast, colon cancer and endometrial cancer. Prognosis is generally ranges from excellent to poor.
Natural History, Complications, and Prognosis
Natural History
- The symptoms of cowden syndrome usually varies and develops in ranging from birth to age 46 years.
- If left untreated, patients with cowden syndrome may prone to develop many cancers.
Complications
- Common complications of cowden syndrome include:[1]
Prognosis
- Prognosis is generally ranges from excellent to poor, and the mortality rate of patients with cowden syndrome is based on malignant tumors associated with it.
- The presence of benign tumours is associated with a particularly poor prognosis among patients with cowden syndrome.
References
- ↑ FitzGerald MG, Marsh DJ, Wahrer D, Bell D, Caron S, Shannon KE, Ishioka C, Isselbacher KJ, Garber JE, Eng C, Haber DA (August 1998). "Germline mutations in PTEN are an infrequent cause of genetic predisposition to breast cancer". Oncogene. 17 (6): 727–31. doi:10.1038/sj.onc.1201984. PMID 9715274.