Coronary heart disease secondary prevention beta-blockers

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Beta Blockers

ACC / AHA 2011 Guidelines - Coronary Heart Disease - Secondary Prevention with Beta Blockers (DO NOT EDIT) [1]

Class I
"1. β-Blocker therapy should be used in all patients with left ventricular systolic dysfunction (ejection fraction ≤40%) with heart failure or prior myocardial infarction, unless contraindicated. (Use should be limited to carvedilol, metoprolol succinate, or bisoprolol, which have been shown to reduce mortality.) (Level A)"
"2.β-Blocker therapy should be started and continued for 3 years in all patients with normal left ventricular function who have had myocardial infarction or ACS. (Level B)"
Class IIa

"1. It is reasonable to continue β-blockers beyond 3 years as chronic therapy in all patients with normal left ventricular function who have had myocardial infarction or ACS. (Level B)"

"2. It is reasonable to give β-blocker therapy in patients with left ventricular systolic dysfunction (ejection fraction ≤40%) without heart failure or prior myocardial infarction.(Level C)"

Class IIb

"1. β-Blockers may be considered as chronic therapy for all other patients with coronary or other vascular disease. (Level C)"

References

  1. Smith SC, Benjamin EJ, Bonow RO, Braun LT, Creager MA, Franklin BA; et al. (2011). "AHA/ACCF Secondary Prevention and Risk Reduction Therapy for Patients with Coronary and other Atherosclerotic Vascular Disease: 2011 update: a guideline from the American Heart Association and American College of Cardiology Foundation". Circulation. 124 (22): 2458–73. doi:10.1161/CIR.0b013e318235eb4d. PMID 22052934.


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