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| __NOTOC__
| | #REDIRECT[[Clostridium difficile]] |
| {{Siren|Clostridium difficile infection}}
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| {{Clostridium difficile infection}}
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| <span style="color:red">'''For more details about the conditions that are associated with the development of ''C. difficile'' infection (e.g. list of antibiotics), click [[Clostridium difficile risk factors|here]]'''</span><br>
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| {{CMG}}; {{AE}} {{YD}}
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| ==Overview==
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| ''C. difficile'' infection is caused by ''Clostridium difficile'', a spore-forming, toxin-producing, oligate anaerobic, gram-positive bacillus.
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| ==Cause of Clostridium difficile infection==
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| ''C. difficile'' infection is caused by ''Clostridium difficile''. ''C. difficile'' has the following characteristic features:
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| *Bacillus
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| *Gram-positive
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| *Obligate anaerobe
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| *Spore-forming (spores are acid-, heat-, and antibiotic-resistant)
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| *Toxin-producing (exotoxins A and B)
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| *Motile<br>
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| ''C. difficile'' is difficult to isolate and grow in cultures. Because the organism is very sensitive to oxygen (obligate anaerobe), spore formation is essential for the organism to be transmitted from one host to another.
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| ==Gallery==
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| <gallery>
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| Image: Clostridium difficile09.jpeg| Clostridium difficile enterotoxin, CPE, is the principal toxin involved in C. difficile foodborne illness. <SMALL><SMALL>''[http://phil.cdc.gov/phil/home.asp From Public Health Image Library (PHIL).] ''<ref name=PHIL> {{Cite web | title = Public Health Image Library (PHIL) | url = http://phil.cdc.gov/phil/home.asp}}</ref></SMALL></SMALL>
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| Image: Clostridium difficile07.jpeg| Gram-positive C. difficile bacteria from a stool sample culture obtained using a .1µm filter. <SMALL><SMALL>''[http://phil.cdc.gov/phil/home.asp From Public Health Image Library (PHIL).] ''<ref name=PHIL> {{Cite web | title = Public Health Image Library (PHIL) | url = http://phil.cdc.gov/phil/home.asp}}</ref></SMALL></SMALL>
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| Image: Clostridium difficile06.jpeg| Gram-positive C. difficile bacteria from a stool sample culture obtained using a .1µm filter. <SMALL><SMALL>''[http://phil.cdc.gov/phil/home.asp From Public Health Image Library (PHIL).] ''<ref name=PHIL> {{Cite web | title = Public Health Image Library (PHIL) | url = http://phil.cdc.gov/phil/home.asp}}</ref></SMALL></SMALL>
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| Image: Clostridium difficile05.jpeg| Gram-positive C. difficile bacteria from a stool sample culture obtained using a .1µm filter. <SMALL><SMALL>''[http://phil.cdc.gov/phil/home.asp From Public Health Image Library (PHIL).] ''<ref name=PHIL> {{Cite web | title = Public Health Image Library (PHIL) | url = http://phil.cdc.gov/phil/home.asp}}</ref></SMALL></SMALL>
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| Image: Clostridium difficile04.jpeg| Gram-positive C. difficile bacteria from a stool sample culture obtained using a .1µm filter. <SMALL><SMALL>''[http://phil.cdc.gov/phil/home.asp From Public Health Image Library (PHIL).] ''<ref name=PHIL> {{Cite web | title = Public Health Image Library (PHIL) | url = http://phil.cdc.gov/phil/home.asp}}</ref></SMALL></SMALL>
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| Image: Clostridium difficile03.jpeg| Gram-positive C. difficile bacteria from a stool sample culture obtained using a .1µm filter. <SMALL><SMALL>''[http://phil.cdc.gov/phil/home.asp From Public Health Image Library (PHIL).] ''<ref name=PHIL> {{Cite web | title = Public Health Image Library (PHIL) | url = http://phil.cdc.gov/phil/home.asp}}</ref></SMALL></SMALL>
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| Image: Clostridium difficile02.jpeg| Illustration depicts the ultrastructural morphology exhibited by a single Gram-positive Clostridium difficile bacillus. <SMALL><SMALL>''[http://phil.cdc.gov/phil/home.asp From Public Health Image Library (PHIL).] ''<ref name=PHIL> {{Cite web | title = Public Health Image Library (PHIL) | url = http://phil.cdc.gov/phil/home.asp}}</ref></SMALL></SMALL>
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| </gallery>
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| ==References==
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| {{Reflist|2}}
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| [[Category:Disease]]
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| [[Category:Gastroenterology]]
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| [[Category:Infectious disease]]
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| [[Category:Bacterial diseases]]
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| {{WH}}
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| {{WS}}
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