Churg-Strauss syndrome natural history, complications and prognosis: Difference between revisions
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===Complications=== | ===Complications=== | ||
*[[Complication (medicine)|Complications]] of [[eosinophilic granulomatosis with polyangiitis]] depend on the specific organ involved in the disease process. | *[[Complication (medicine)|Complications]] of [[eosinophilic granulomatosis with polyangiitis]] depend on the specific organ involved in the disease process. | ||
**Heart:<ref name="pmid21138993">{{cite journal |vauthors=Aakerøy L, Amundsen BH, Skomsvoll JF, Haugen BO, Soma J |title=A 50-year-old man with eosinophilia and cardiomyopathy: need for endomyocardial biopsy? |journal=Eur J Echocardiogr |volume=12 |issue=3 |pages=257–9 |date=March 2011 |pmid=21138993 |doi=10.1093/ejechocard/jeq167 |url=}}</ref> | **[[Heart|'''Heart''']]:<ref name="pmid21138993">{{cite journal |vauthors=Aakerøy L, Amundsen BH, Skomsvoll JF, Haugen BO, Soma J |title=A 50-year-old man with eosinophilia and cardiomyopathy: need for endomyocardial biopsy? |journal=Eur J Echocardiogr |volume=12 |issue=3 |pages=257–9 |date=March 2011 |pmid=21138993 |doi=10.1093/ejechocard/jeq167 |url=}}</ref> | ||
***Pericarditis | ***[[Pericarditis]] | ||
***Myocarditis | ***[[Myocarditis]] | ||
***Pericardial effusion | ***[[Pericardial effusion]] | ||
***Myocardial infarction | ***[[Myocardial infarction]] | ||
***Cardiac tamponade | ***[[Cardiac tamponade]] | ||
**Lung:<ref name="pmid9645420">{{cite journal |vauthors=Lai RS, Lin SL, Lai NS, Lee PC |title=Churg-Strauss syndrome presenting with pulmonary capillaritis and diffuse alveolar hemorrhage |journal=Scand. J. Rheumatol. |volume=27 |issue=3 |pages=230–2 |date=1998 |pmid=9645420 |doi= |url=}}</ref> | **[[Lung|'''Lung''']]:<ref name="pmid9645420">{{cite journal |vauthors=Lai RS, Lin SL, Lai NS, Lee PC |title=Churg-Strauss syndrome presenting with pulmonary capillaritis and diffuse alveolar hemorrhage |journal=Scand. J. Rheumatol. |volume=27 |issue=3 |pages=230–2 |date=1998 |pmid=9645420 |doi= |url=}}</ref> | ||
***Pleural effusion | ***[[Pleural effusion]] | ||
***Pulmonary hypertension | ***[[Pulmonary hypertension]] | ||
***Alveolar hemorrhage | ***Alveolar hemorrhage | ||
**Kidney:<ref name="pmid2113641">{{cite journal |vauthors=Clutterbuck EJ, Evans DJ, Pusey CD |title=Renal involvement in Churg-Strauss syndrome |journal=Nephrol. Dial. Transplant. |volume=5 |issue=3 |pages=161–7 |date=1990 |pmid=2113641 |doi= |url=}}</ref> | **[[Kidney|'''Kidney''']]:<ref name="pmid2113641">{{cite journal |vauthors=Clutterbuck EJ, Evans DJ, Pusey CD |title=Renal involvement in Churg-Strauss syndrome |journal=Nephrol. Dial. Transplant. |volume=5 |issue=3 |pages=161–7 |date=1990 |pmid=2113641 |doi= |url=}}</ref> | ||
***Glomerulonephritis | ***[[Glomerulonephritis]] | ||
***Renal failure | ***[[Renal insufficiency|Renal failure]] | ||
**GI tract:<ref name="pmid9497232">{{cite journal |vauthors=Kaneki T, Kawashima A, Hayano T, Honda T, Kubo K, Koizumi T, Sekiguchi M, Ichikawa H, Matsuzawa K, Katsuyama T |title=Churg-Strauss syndrome (allergic granulomatous angitis) presenting with ileus caused by ischemic ileal ulcer |journal=J. Gastroenterol. |volume=33 |issue=1 |pages=112–6 |date=February 1998 |pmid=9497232 |doi= |url=}}</ref> | **[[Gastrointestinal tract|'''GI tract''']]:<ref name="pmid9497232">{{cite journal |vauthors=Kaneki T, Kawashima A, Hayano T, Honda T, Kubo K, Koizumi T, Sekiguchi M, Ichikawa H, Matsuzawa K, Katsuyama T |title=Churg-Strauss syndrome (allergic granulomatous angitis) presenting with ileus caused by ischemic ileal ulcer |journal=J. Gastroenterol. |volume=33 |issue=1 |pages=112–6 |date=February 1998 |pmid=9497232 |doi= |url=}}</ref> | ||
***Gastrointestinal bleeding | ***[[Gastrointestinal bleeding]] | ||
***Acute abdominal pain or intestinal angina | ***[[Abdominal pain|Acute abdominal pain]] or intestinal angina | ||
**Neurologic:<ref name="pmid20050889">{{cite journal |vauthors=Wolf J, Bergner R, Mutallib S, Buggle F, Grau AJ |title=Neurologic complications of Churg-Strauss syndrome--a prospective monocentric study |journal=Eur. J. Neurol. |volume=17 |issue=4 |pages=582–8 |date=April 2010 |pmid=20050889 |doi=10.1111/j.1468-1331.2009.02902.x |url=}}</ref> | **'''Neurologic''':<ref name="pmid20050889">{{cite journal |vauthors=Wolf J, Bergner R, Mutallib S, Buggle F, Grau AJ |title=Neurologic complications of Churg-Strauss syndrome--a prospective monocentric study |journal=Eur. J. Neurol. |volume=17 |issue=4 |pages=582–8 |date=April 2010 |pmid=20050889 |doi=10.1111/j.1468-1331.2009.02902.x |url=}}</ref> | ||
***peripheral neuropathy | ***[[peripheral neuropathy]] | ||
***Cerebral hemorrhage | ***[[Intracranial hemorrhage|Cerebral hemorrhage]] | ||
**Skin:<ref name="pmid19569284">{{cite journal |vauthors=Lestre S, Serrão V, João A, Pinheiro S, Lobo L |title=[Churg-Strauss syndrome presenting with cutaneous vasculitis] |language=Portuguese |journal=Acta Reumatol Port |volume=34 |issue=2A |pages=281–7 |date=2009 |pmid=19569284 |doi= |url=}}</ref> | **[[Skin|'''Skin''']]:<ref name="pmid19569284">{{cite journal |vauthors=Lestre S, Serrão V, João A, Pinheiro S, Lobo L |title=[Churg-Strauss syndrome presenting with cutaneous vasculitis] |language=Portuguese |journal=Acta Reumatol Port |volume=34 |issue=2A |pages=281–7 |date=2009 |pmid=19569284 |doi= |url=}}</ref> | ||
***Purpura | ***[[Purpura]] | ||
***Petichiae | ***[[Petechia|Petichiae]] | ||
***Noduluar lesions on extensor surfaces | ***Noduluar lesions on extensor surfaces | ||
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief:
Overview
If left untreated, [#]% of patients with [disease name] may progress to develop [manifestation 1], [manifestation 2], and [manifestation 3].
OR
Common complications of [disease name] include [complication 1], [complication 2], and [complication 3].
OR
Prognosis is generally excellent/good/poor, and the 1/5/10-year mortality/survival rate of patients with [disease name] is approximately [#]%.
Natural History, Complications, and Prognosis
Natural History
- The symptoms of (disease name) usually develop in the first/ second/ third decade of life, and start with symptoms such as ___.
- The symptoms of (disease name) typically develop ___ years after exposure to ___.
- If left untreated, [#]% of patients with [disease name] may progress to develop [manifestation 1], [manifestation 2], and [manifestation 3].
Complications
- Complications of eosinophilic granulomatosis with polyangiitis depend on the specific organ involved in the disease process.
- Heart:[1]
- Lung:[2]
- Pleural effusion
- Pulmonary hypertension
- Alveolar hemorrhage
- Kidney:[3]
- GI tract:[4]
- Gastrointestinal bleeding
- Acute abdominal pain or intestinal angina
- Neurologic:[5]
- Skin:[6]
Prognosis
- Prognosis is generally excellent/good/poor, and the 1/5/10-year mortality/survival rate of patients with [disease name] is approximately [#]%.
- Depending on the extent of the [tumor/disease progression/etc.] at the time of diagnosis, the prognosis may vary. However, the prognosis is generally regarded as poor/good/excellent.
- The presence of [characteristic of disease] is associated with a particularly [good/poor] prognosis among patients with [disease/malignancy].
- [Subtype of disease/malignancy] is associated with the most favorable prognosis.
- The prognosis varies with the [characteristic] of tumor; [subtype of disease/malignancy] have the most favorable prognosis.
References
- ↑ Aakerøy L, Amundsen BH, Skomsvoll JF, Haugen BO, Soma J (March 2011). "A 50-year-old man with eosinophilia and cardiomyopathy: need for endomyocardial biopsy?". Eur J Echocardiogr. 12 (3): 257–9. doi:10.1093/ejechocard/jeq167. PMID 21138993.
- ↑ Lai RS, Lin SL, Lai NS, Lee PC (1998). "Churg-Strauss syndrome presenting with pulmonary capillaritis and diffuse alveolar hemorrhage". Scand. J. Rheumatol. 27 (3): 230–2. PMID 9645420.
- ↑ Clutterbuck EJ, Evans DJ, Pusey CD (1990). "Renal involvement in Churg-Strauss syndrome". Nephrol. Dial. Transplant. 5 (3): 161–7. PMID 2113641.
- ↑ Kaneki T, Kawashima A, Hayano T, Honda T, Kubo K, Koizumi T, Sekiguchi M, Ichikawa H, Matsuzawa K, Katsuyama T (February 1998). "Churg-Strauss syndrome (allergic granulomatous angitis) presenting with ileus caused by ischemic ileal ulcer". J. Gastroenterol. 33 (1): 112–6. PMID 9497232.
- ↑ Wolf J, Bergner R, Mutallib S, Buggle F, Grau AJ (April 2010). "Neurologic complications of Churg-Strauss syndrome--a prospective monocentric study". Eur. J. Neurol. 17 (4): 582–8. doi:10.1111/j.1468-1331.2009.02902.x. PMID 20050889.
- ↑ Lestre S, Serrão V, João A, Pinheiro S, Lobo L (2009). "[Churg-Strauss syndrome presenting with cutaneous vasculitis]". Acta Reumatol Port (in Portuguese). 34 (2A): 281–7. PMID 19569284.