Churg-Strauss syndrome history and symptoms
|
Churg-Strauss syndrome Microchapters |
|
Diagnosis |
|---|
|
Treatment |
|
Case Studies |
|
Churg-Strauss syndrome history and symptoms On the Web |
|
American Roentgen Ray Society Images of Churg-Strauss syndrome history and symptoms |
|
Risk calculators and risk factors for Churg-Strauss syndrome history and symptoms |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Ali Poyan Mehr, M.D. [2]Associate Editor(s)-in-Chief: Chandrakala Yannam, MD [3]
Overview
The majority of patients with [disease name] are asymptomatic.
OR
The hallmark of [disease name] is [finding]. A positive history of [finding 1] and [finding 2] is suggestive of [disease name]. The most common symptoms of [disease name] include [symptom 1], [symptom 2], and [symptom 3]. Common symptoms of [disease] include [symptom 1], [symptom 2], and [symptom 3]. Less common symptoms of [disease name] include [symptom 1], [symptom 2], and [symptom 3].
History and Symptoms
- Obtaining a complete history is an important aspect in making a diagnosis of eosinophilic granulomatosis with polyangiitis. As it can help differentiate between the ANCA associated vasculitis and other possible causes that may mimic the disease.
- Symptoms of eosinophilic granulomatosis with polyangiitis typically develops through three phases, include prodromal phase, eosinophilic phase, and vasculitis phase. Although these phases cannot be clinically distinguishable.[1][2][3][4]
- Prodromal phase: Most common manifestations include allergic rhinitis and asthma.
- Eosinophilic phase: This phase is characterized by peripheral eosinophilia and infiltration of eosinophils in multiple organs. Most commonly involved organs are lung and GI tract.
- Vasculitic phase: This phase is characterized by small and medium-sized vasculitis and inflammatory granuloma formation. Granulomas can be either vascular or extravascular. Commonly involved organs include lungs, kidneys, skin, heart, and peripheral nerves.
- The following are history and symptoms of eosinophilic granulomatosis with polyangiitis:[2]
- Constitutional Symptoms:
- Involvement of ear, nose and throat:
- Sinusitis
- Allergic rhinitis
- Otitis media
- Nasal polyposis
- Sensorineural hearing loss
- Pulmonary involvement:[5]
- Involvement of GI tract:
- Acute abdomen or intestinal angina
- Bleeding
- Diarrhea
- Vomitings
- Cardiac involvement:[6]
- Arrythmia
- Symptoms related to
- Skin involvement:[7]
- Skin nodules on extensor surfaces of arm, legs
- Urticarial rash
- Ecchymosis
- Purpura
- Petechiae
- Renal involvement:[8]
- Nervous system involvement:[9]
References
- ↑ Lanham JG, Elkon KB, Pusey CD, Hughes GR (March 1984). "Systemic vasculitis with asthma and eosinophilia: a clinical approach to the Churg-Strauss syndrome". Medicine (Baltimore). 63 (2): 65–81. PMID 6366453.
- ↑ 2.0 2.1 Guillevin L, Cohen P, Gayraud M, Lhote F, Jarrousse B, Casassus P (January 1999). "Churg-Strauss syndrome. Clinical study and long-term follow-up of 96 patients". Medicine (Baltimore). 78 (1): 26–37. PMID 9990352.
- ↑ Oh MJ, Lee JY, Kwon NH, Choi DC (April 2006). "Churg-Strauss syndrome: the clinical features and long-term follow-up of 17 patients". J. Korean Med. Sci. 21 (2): 265–71. doi:10.3346/jkms.2006.21.2.265. PMC 2734002. PMID 16614512.
- ↑ Greco A, Rizzo MI, De Virgilio A, Gallo A, Fusconi M, Ruoppolo G, Altissimi G, De Vincentiis M (April 2015). "Churg-Strauss syndrome". Autoimmun Rev. 14 (4): 341–8. doi:10.1016/j.autrev.2014.12.004. PMID 25500434.
- ↑ Yılmaz İ, Tutar N, Şimşek ZÖ, Oymak FS, Gülmez İ (July 2017). "Clinical and Serological Features of Eosinophilic and Vasculitic Phases of Eosinophilic Granulomatosis with Poliangiitis: a Case Series of 15 Patients". Turk Thorac J. 18 (3): 72–77. doi:10.5152/TurkThoracJ.2017.16040. PMC 5783085. PMID 29404165.
- ↑ Neumann T, Manger B, Schmid M, Kroegel C, Hansch A, Kaiser WA, Reinhardt D, Wolf G, Hein G, Mall G, Schett G, Zwerina J (July 2009). "Cardiac involvement in Churg-Strauss syndrome: impact of endomyocarditis". Medicine (Baltimore). 88 (4): 236–43. doi:10.1097/MD.0b013e3181af35a5. PMID 19593229.
- ↑ Marques CC, Fernandes EL, Miquelin GM, Colferai M (2017). "Cutaneous manifestations of Churg-Strauss syndrome: key to diagnosis". An Bras Dermatol. 92 (5 Suppl 1): 56–58. doi:10.1590/abd1806-4841.20175522. PMC 5726678. PMID 29267447. Vancouver style error: initials (help)
- ↑ Clutterbuck EJ, Evans DJ, Pusey CD (1990). "Renal involvement in Churg-Strauss syndrome". Nephrol. Dial. Transplant. 5 (3): 161–7. PMID 2113641.
- ↑ Wolf J, Bergner R, Mutallib S, Buggle F, Grau AJ (April 2010). "Neurologic complications of Churg-Strauss syndrome--a prospective monocentric study". Eur. J. Neurol. 17 (4): 582–8. doi:10.1111/j.1468-1331.2009.02902.x. PMID 20050889.