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{{Cholangitis}}
{{Cholangitis}}
==Overview==
==Overview==
The classical clinical manifestation of [[Cholangitis]] is described by [[Charcot's triad]] and includes [[fever]], right upper quadrant pain, and [[jaundice]]. In suppurative cholangitis [[hypotension]], and [[confusion]] can occur. The pentad of presentation is then called as '''[[Reynold's pentad]]'''. Reynold's pentad is associated with significant morbidity, and mortality.
The classical clinical manifestation of [[Cholangitis]] is described by [[Charcot's triad]] and includes [[fever]], right upper quadrant pain, and [[jaundice]]. In suppurative cholangitis [[hypotension]], and [[confusion]] can occur. The pentad of presentation is then called as Reynold's pentad. Reynold's pentad is associated with significant morbidity, and mortality.


==History and Symptoms==
==History and Symptoms==

Revision as of 03:35, 22 February 2013

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

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Overview

The classical clinical manifestation of Cholangitis is described by Charcot's triad and includes fever, right upper quadrant pain, and jaundice. In suppurative cholangitis hypotension, and confusion can occur. The pentad of presentation is then called as Reynold's pentad. Reynold's pentad is associated with significant morbidity, and mortality.

History and Symptoms

The three classical presentation of Charcot’s triad are present only in 50-60% of the patient population. 95% patients may have fever, 66% abdominal pain, and jaundice is noted in 80% (with a bilirubin >2.5). Nonobstructive stones are more likely to present without pain or fever. Elderly patients may present only with hypotension.

Charcot's Triad

Abdominal Pain

  • right or middle of the upper abdomen
  • Intermittent
  • Sharp, crampy, or dull
  • Radiation to back or below the right shoulder blade

Fever

  • With chills and rigor

Jaundice

  • Clay-colored stools
  • Dark urine
  • Nausea and vomiting
  • Yellowing of the skin and sclera

Reynold's Pentad

  • In suppurative cholangitis hypotension, and confusion can occur along with Charcot's triad. The pentad of presentation is then called as Reynold's pentad.
  • Reynold's pentad is associated with significant morbidity, and mortality.

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