Chlorproethazine: Difference between revisions

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Latest revision as of 19:01, 18 August 2015

Template:Chembox E number
Chlorproethazine
Names
IUPAC name
3-(2-chlorophenothiazin-10-yl)-N,N-diethylpropan-1-amine
Identifiers
3D model (JSmol)
ChEMBL
ChemSpider
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KEGG
Properties
C19H23ClN2S
Molar mass 346.91732 g/mol
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Infobox references

WikiDoc Resources for Chlorproethazine

Articles

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Most cited articles on Chlorproethazine

Review articles on Chlorproethazine

Articles on Chlorproethazine in N Eng J Med, Lancet, BMJ

Media

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Evidence Based Medicine

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TRIP on Chlorproethazine

Clinical Trials

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Guidelines / Policies / Govt

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NICE Guidance on Chlorproethazine

NHS PRODIGY Guidance

FDA on Chlorproethazine

CDC on Chlorproethazine

Books

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News

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Commentary

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Definitions

Definitions of Chlorproethazine

Patient Resources / Community

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Risk calculators and risk factors for Chlorproethazine

Healthcare Provider Resources

Symptoms of Chlorproethazine

Causes & Risk Factors for Chlorproethazine

Diagnostic studies for Chlorproethazine

Treatment of Chlorproethazine

Continuing Medical Education (CME)

CME Programs on Chlorproethazine

International

Chlorproethazine en Espanol

Chlorproethazine en Francais

Business

Chlorproethazine in the Marketplace

Patents on Chlorproethazine

Experimental / Informatics

List of terms related to Chlorproethazine

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Chlorproethazine is an antipsychotic.

Synthesis

Chlorproethazine can be synthesized from a diphenylsulfide derivative. The general scheme is sufficiently flexible to permit the interchange of the order of some of the steps.

Thus alkylation of aniline thioether () with 3-chloro-1-diethylaminopropane leads to the intermediate (). Ring closure as above by nucleophilic aromatic displacement leads to the antipsychotic drug chlorproethazine.[1]

References

  1. Buisson, P.; Gailliot, P.; 1956, Template:US Patent