3D model (JSmol)
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|Except where noted otherwise, data are given for|
materials in their standard state
(at 25 °C, 100 kPa)
Infobox disclaimer and references
Butyrophenone is a chemical compound (a ketone); some of its derivatives (called commonly butyrophenones) are used to treat various psychiatric disorders such as schizophrenia, as well as acting as antiemetics.
Butyrophenones are a class of pharmaceutical drugs derived from butyrophenone.
- Haloperidol, the most widely-used drug in this class
- Droperidol, often used for neuroleptanalgesic anesthesia and sedation in intensive-care treatment
- Benperidol, the most potent commonly-used antipsychotic (~ 200 times more potent as chlorpromazine)
- Triperidol, a highly-potent antipsychotic (100 times more potent than chlorpromazine)
- Melperone, a weakly-potent antipsychotic, in Europe commonly used for treatment of insomnia, confusional states, psychomotor agitation, and delirium, in particular, in geriatric patients
- Domperidone, an dopamine-antagonist antiemetic, derived further from butyrophenone (not being a butyrophenone itself).