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==Overview==
==Overview==
Carcinoid syndrome was first described by Siegfried Oberndorfer, a German [[pathologist]] in 1907. Endocrine related properties of carcinoids was described by Gosset and Masson in 1914.<ref name="pmid24713679">{{cite journal| author=Tsoucalas G, Karamanou M, Androutsos G| title=The eminent German pathologist Siegfried Oberndorfer (1876-1944) and his landmark work on carcinoid tumors. | journal=Ann Gastroenterol | year= 2011 | volume= 24 | issue= 2 | pages= 98-100 | pmid=24713679 | doi= | pmc=PMC3959292 | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=24713679  }} </ref>
Carcinoid syndrome was first described by Siegfried Oberndorfer, a German [[pathologist]] in 1907. Endocrine related properties of carcinoids was described by Gosset and Masson in 1914.<ref name="pmid24713679">{{cite journal| author=Tsoucalas G, Karamanou M, Androutsos G| title=The eminent German pathologist Siegfried Oberndorfer (1876-1944) and his landmark work on carcinoid tumors. | journal=Ann Gastroenterol | year= 2011 | volume= 24 | issue= 2 | pages= 98-100 | pmid=24713679 | doi= | pmc=PMC3959292 | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=24713679 }} </ref><ref name="pmid3959292">{{cite journal| author=Swiryn S, Hueter DC| title=The electrocardiogram in esophageal impaction. | journal=JAMA | year= 1986 | volume= 255 | issue= 15 | pages= 2067-8 | pmid=3959292 | doi= | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=3959292 }} </ref>
==Historical Perspective==
==Historical Perspective==
Carcinoid syndrome was first described in 1907 by Siegfried Oberndorfer, a German [[pathologist]] at the University of Munich, who coined the term ''karzinoide'', or "carcinoma-like", to describe the unique feature of behaving like a [[benign tumor]] despite having a [[malignant]] appearance microscopically.<ref name="pmid3959292">{{cite journal| author=Swiryn S, Hueter DC| title=The electrocardiogram in esophageal impaction. | journal=JAMA | year= 1986 | volume= 255 | issue= 15 | pages= 2067-8 | pmid=3959292 | doi= | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=3959292  }} </ref> The recognition of their endocrine-related properties were later described by Gosset and Masson in 1914, and these tumors are now known to arise from the [[enterochromaffin]] (EC) and enterochromaffin-like (ECL) cells of the gut.<ref name="pmid24713679">{{cite journal| author=Tsoucalas G, Karamanou M, Androutsos G| title=The eminent German pathologist Siegfried Oberndorfer (1876-1944) and his landmark work on carcinoid tumors. | journal=Ann Gastroenterol | year= 2011 | volume= 24 | issue= 2 | pages= 98-100 | pmid=24713679 | doi= | pmc=PMC3959292 | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=24713679  }} </ref>
Carcinoid syndrome was first described in 1907 by Siegfried Oberndorfer, a German [[pathologist]] at the University of Munich, who coined the term ''karzinoide'', or "carcinoma-like", to describe the unique feature of behaving like a [[benign tumor]] despite having a [[malignant]] appearance microscopically.<ref name="pmid3959292">{{cite journal| author=Swiryn S, Hueter DC| title=The electrocardiogram in esophageal impaction. | journal=JAMA | year= 1986 | volume= 255 | issue= 15 | pages= 2067-8 | pmid=3959292 | doi= | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=3959292  }} </ref> The recognition of their endocrine-related properties were later described by Gosset and Masson in 1914, and these tumors are now known to arise from the [[enterochromaffin]] (EC) and enterochromaffin-like (ECL) cells of the gut.<ref name="pmid24713679">{{cite journal| author=Tsoucalas G, Karamanou M, Androutsos G| title=The eminent German pathologist Siegfried Oberndorfer (1876-1944) and his landmark work on carcinoid tumors. | journal=Ann Gastroenterol | year= 2011 | volume= 24 | issue= 2 | pages= 98-100 | pmid=24713679 | doi= | pmc=PMC3959292 | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=24713679  }} </ref>

Revision as of 15:14, 29 September 2015

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Parminder Dhingra, M.D. [2]

Overview

Carcinoid syndrome was first described by Siegfried Oberndorfer, a German pathologist in 1907. Endocrine related properties of carcinoids was described by Gosset and Masson in 1914.[1][2]

Historical Perspective

Carcinoid syndrome was first described in 1907 by Siegfried Oberndorfer, a German pathologist at the University of Munich, who coined the term karzinoide, or "carcinoma-like", to describe the unique feature of behaving like a benign tumor despite having a malignant appearance microscopically.[2] The recognition of their endocrine-related properties were later described by Gosset and Masson in 1914, and these tumors are now known to arise from the enterochromaffin (EC) and enterochromaffin-like (ECL) cells of the gut.[1]

References

  1. 1.0 1.1 Tsoucalas G, Karamanou M, Androutsos G (2011). "The eminent German pathologist Siegfried Oberndorfer (1876-1944) and his landmark work on carcinoid tumors". Ann Gastroenterol. 24 (2): 98–100. PMC 3959292. PMID 24713679.
  2. 2.0 2.1 Swiryn S, Hueter DC (1986). "The electrocardiogram in esophageal impaction". JAMA. 255 (15): 2067–8. PMID 3959292.

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