Burkitt's lymphoma staging: Difference between revisions

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Latest revision as of 23:11, 18 January 2019

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Sowminya Arikapudi, M.B,B.S. [2], Kamal Akbar, M.D.[3]

Overview

According to the Murphy staging system, there are four stages of Burkitt's lymphoma based on the number of nodes involved and the extra nodal spread.

Staging

According to the Murphy staging system, there are four stages of Burkitt's lymphoma based on the number of nodes involved and the extra nodal spread.

Staging for Burkitt's lymphoma is provided in the following table:^[1]

**Murphy staging system**
Stage	Features
Stage I	Single nodal or extra nodal site involvement excluding mediastinum or abdomen^[2]
Stage II	Single extra nodal tumor with regional nodal involvement Two extra nodal tumors on one side of diaphragm^[2] Primary gastrointestinal tumor with or without associated mesenteric nodes Two or more nodal areas on one side of diaphragm
Stage IIR	Completely resected intra-abdominal disease
Stage III	Two single extra nodal tumors on opposite sides of diaphragm ^[2] All primary intra thoracic tumors All paraspinal or epidural tumors All extensive primary intra-abdominal disease Two or more nodal areas on opposite sides of diaphragm
Stage IIIA	Localized, non-resectable abdominal disease
Stage IIIB	Widespread multi organ abdominal disease
Stage IV	Initial CNS or bone marrow involvement (< 25%)

References

↑ Perkins AS, Friedberg JW (2008). "Burkitt lymphoma in adults". Hematology Am Soc Hematol Educ Program: 341–8. doi:10.1182/asheducation-2008.1.341. PMID 19074108.
↑ ^2.0 ^2.1 ^2.2 Sandlund JT (2012). "Burkitt lymphoma: staging and response evaluation". Br J Haematol. 156 (6): 761–5. doi:10.1111/j.1365-2141.2012.09026.x. PMC 3292702. PMID 22296338.

Template:Hematology

Template:WikiDoc Sources

[pmid19074108-1] Perkins AS, Friedberg JW (2008). "Burkitt lymphoma in adults". Hematology Am Soc Hematol Educ Program: 341–8. doi:10.1182/asheducation-2008.1.341. PMID 19074108.

[pmid22296338-2] 2.0 ^2.1 ^2.2 Sandlund JT (2012). "Burkitt lymphoma: staging and response evaluation". Br J Haematol. 156 (6): 761–5. doi:10.1111/j.1365-2141.2012.09026.x. PMC 3292702. PMID 22296338.

[1]

[2]

@@ Line 10: / Line 10: @@
 Staging for Burkitt's lymphoma is provided in the following table:<ref name="pmid19074108">{{cite journal| author=Perkins AS, Friedberg JW| title=Burkitt lymphoma in adults. | journal=Hematology Am Soc Hematol Educ Program | year= 2008 | volume=  | issue=  | pages= 341-8 | pmid=19074108 | doi=10.1182/asheducation-2008.1.341 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=19074108  }} </ref>
-{| style="border: 0px; font-size: 90%; margin: 3px;" align=center
+{| style="border: 0px; font-size: 90%; margin: 3px;" align="center"
 |+ '''Murphy staging system'''
 ! style="background: #4479BA; color:#FFF;" | Stage
@@ Line 17: / Line 17: @@
 | style="padding: 5px 5px; background: #F5F5F5;" | Stage I
 | style="padding: 5px 5px; background: #F5F5F5;" |
-* Single nodal or extra nodal site involvement excluding mediastinum or abdomen<ref name="pmid22296338">{{cite journal| author=Sandlund JT| title=Burkitt lymphoma: staging and response evaluation. | journal=Br J Haematol | year= 2012 | volume= 156 | issue= 6 | pages= 761-5 | pmid=22296338 | doi=10.1111/j.1365-2141.2012.09026.x | pmc=3292702 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=22296338  }} </ref>
+* Single nodal or extra nodal site involvement excluding [[mediastinum]] or abdomen<ref name="pmid22296338">{{cite journal| author=Sandlund JT| title=Burkitt lymphoma: staging and response evaluation. | journal=Br J Haematol | year= 2012 | volume= 156 | issue= 6 | pages= 761-5 | pmid=22296338 | doi=10.1111/j.1365-2141.2012.09026.x | pmc=3292702 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=22296338  }} </ref>
 |-
 | style="padding: 5px 5px; background: #F5F5F5;" | Stage II
 | style="padding: 5px 5px; background: #F5F5F5;" |
-* Single extra nodal tumor with regional nodal involvement
+* Single extra nodal [[tumor]] with regional [[Lymph node|nodal]] involvement
-* Two extra nodal tumors on one side of diaphragm<ref name="pmid22296338">{{cite journal| author=Sandlund JT| title=Burkitt lymphoma: staging and response evaluation. | journal=Br J Haematol | year= 2012 | volume= 156 | issue= 6 | pages= 761-5 | pmid=22296338 | doi=10.1111/j.1365-2141.2012.09026.x | pmc=3292702 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=22296338  }} </ref>
+* Two extra nodal [[tumors]] on one side of [[diaphragm]]<ref name="pmid22296338">{{cite journal| author=Sandlund JT| title=Burkitt lymphoma: staging and response evaluation. | journal=Br J Haematol | year= 2012 | volume= 156 | issue= 6 | pages= 761-5 | pmid=22296338 | doi=10.1111/j.1365-2141.2012.09026.x | pmc=3292702 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=22296338  }} </ref>
-* Primary gastrointestinal tumor with or without associated mesenteric nodes
+* Primary [[Gastrointestinal tract|gastrointestinal]] [[tumor]] with or without associated [[mesenteric]] [[Lymph node|nodes]]
-* Two or more nodal areas on one side of diaphragm
+* Two or more [[Lymph node|nodal]] areas on one side of [[diaphragm]]
 |-
 | style="padding: 5px 5px; background: #F5F5F5;" | Stage IIR
 | style="padding: 5px 5px; background: #F5F5F5;" |
-* Completely resected intra-abdominal disease
+* Completely resected intra-[[abdominal]] disease
 |-
 | style="padding: 5px 5px; background: #F5F5F5;" | Stage III
 | style="padding: 5px 5px; background: #F5F5F5;" |
-* Two single extra nodal tumors on opposite sides of diaphragm <ref name="pmid22296338">{{cite journal| author=Sandlund JT| title=Burkitt lymphoma: staging and response evaluation. | journal=Br J Haematol | year= 2012 | volume= 156 | issue= 6 | pages= 761-5 | pmid=22296338 | doi=10.1111/j.1365-2141.2012.09026.x | pmc=3292702 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=22296338  }} </ref>
+* Two single extra [[Lymph node|nodal]] tumors on opposite sides of [[diaphragm]] <ref name="pmid22296338">{{cite journal| author=Sandlund JT| title=Burkitt lymphoma: staging and response evaluation. | journal=Br J Haematol | year= 2012 | volume= 156 | issue= 6 | pages= 761-5 | pmid=22296338 | doi=10.1111/j.1365-2141.2012.09026.x | pmc=3292702 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=22296338  }} </ref>
-* All primary intra thoracic tumors
+* All primary intra thoracic [[tumors]]
-* All paraspinal or epidural tumors
+* All paraspinal or epidural [[tumors]]
 * All extensive primary intra-abdominal disease
-* Two or more nodal areas on opposite sides of diaphragm
+* Two or more nodal areas on opposite sides of [[diaphragm]]
 |-
 | style="padding: 5px 5px; background: #F5F5F5;" | Stage IIIA
 | style="padding: 5px 5px; background: #F5F5F5;" |
-* Localized, non-resectable abdominal disease
+* Localized, non-resectable [[abdominal]] disease
 |-
 | style="padding: 5px 5px; background: #F5F5F5;" | Stage IIIB
 | style="padding: 5px 5px; background: #F5F5F5;" |
-* Widespread multi organ abdominal disease
+* Widespread multi organ [[abdominal]] disease
 |-
 | style="padding: 5px 5px; background: #F5F5F5;" | Stage IV
 | style="padding: 5px 5px; background: #F5F5F5;" |
-* Initial CNS or bone marrow involvement (< 25%)
+* Initial CNS or [[bone marrow]] involvement (< 25%)
 |}

v t e Myeloid Hematological malignancy/leukemia histology (ICD-O 9590-9989, C81-C96, 200-208)
CFU-GM/ and other granulocytes	Template:Navbox subgroup
MEP	Template:Navbox subgroup
CFU-Mast	Mastocytoma (Mast cell leukemia, Mast cell sarcoma, Systemic mastocytosis)
Multiple/unknown	AML (Acute panmyelosis with myelofibrosis, Myeloid sarcoma) · MP (Myelofibrosis) · Acute biphenotypic leukaemia
See also hematology, lymphoid malignancy

Burkitt's lymphoma staging: Difference between revisions

Latest revision as of 23:11, 18 January 2019

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