Burkitt's lymphoma staging

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Sowminya Arikapudi, M.B,B.S. [2], Kamal Akbar, M.D.[3]

Overview

According to the Murphy staging system, there are four stages of Burkitt's lymphoma based on the number of nodes involved and the extra nodal spread.

Staging

According to the Murphy staging system, there are four stages of Burkitt's lymphoma based on the number of nodes involved and the extra nodal spread.

Staging for Burkitt's lymphoma is provided in the following table:[1]

Murphy staging system
Stage Features
Stage I
  • Single nodal or extra nodal site involvement excluding mediastinum or abdomen[2]
Stage II
Stage IIR
Stage III
  • Two single extra nodal tumors on opposite sides of diaphragm [2]
  • All primary intra thoracic tumors
  • All paraspinal or epidural tumors
  • All extensive primary intra-abdominal disease
  • Two or more nodal areas on opposite sides of diaphragm
Stage IIIA
Stage IIIB
Stage IV

References

  1. Perkins AS, Friedberg JW (2008). "Burkitt lymphoma in adults". Hematology Am Soc Hematol Educ Program: 341–8. doi:10.1182/asheducation-2008.1.341. PMID 19074108.
  2. 2.0 2.1 2.2 Sandlund JT (2012). "Burkitt lymphoma: staging and response evaluation". Br J Haematol. 156 (6): 761–5. doi:10.1111/j.1365-2141.2012.09026.x. PMC 3292702. PMID 22296338.

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