Bullous pemphigoid: Difference between revisions

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{{DiseaseDisorder infobox |
{{DiseaseDisorder infobox |
   Name        = Bullous pemphigoid |
   Name        = Bullous pemphigoid |
  Image      = Bullous pemphigoid.jpg |
Image      = Bullous pemphigoid.jpg |
  ICD10      = {{ICD10|L|12|0|l|10}} |
  ICD9        = {{ICD9|694.5}} |
}}
}}
__NOTOC__
__NOTOC__
{{SI}}
{{CMG}};{{AE}} {{KS}}
{{CMG}};{{AE}} {{KS}}


==Overview==
==Overview==
'''Bullous pemphigoid''', also referred to as '''BP''', is a chronic [[autoimmune disorder|autoimmune]] [[skin disease]], involving the formation of [[blisters]] below the surface of the skin and antibodies against the type XVII collagen component of [[hemidesmosomes]]. It can also (albeit only rarely) involve the [[mucous membrane]]s, and has been shown to afflict dogs, cats, pigs, and horses, as well as humans.
'''Bullous pemphigoid''', also referred to as '''BP''', is a chronic [[autoimmune disorder|autoimmune]] [[skin disease]], involving the formation of [[blisters]] below the surface of the skin and antibodies against the type XVII collagen component of [[hemidesmosomes]]. It can also (albeit only rarely) involve the [[mucous membrane]]s, and has been shown to afflict dogs, cats, pigs, and horses, as well as humans.
==Historical Perspective==
==Classification==
==Pathophysiology==
==Causes==
==Differentiating Bullous Pemphigoid from Other Diseases==
==Epidemiology and Demographics==
===Age===
===Gender===
===Race===
==Risk Factors==
==Natural History, Complications and Prognosis==


==Diagnosis==
==Diagnosis==
===Diagnostic Criteria===
===Symptoms===
===Physical Examination===
===Physical Examination===
====Skin====
====Skin====
=====Extremity=====
=====Extremity=====
<gallery>
<gallery>
Image:Bullous pemphigoid01.jpg|Bullous pemphigoid. <SMALL><SMALL>''[http://www.atlasdermatologico.com.br/  Permission from Dermatology Atlas.]''<ref name="Dermatology Atlas">{{Cite web | title = Dermatology Atlas | url = http://www.atlasdermatologico.com.br/}}</ref></SMALL></SMALL>
Image:Bullous pemphigoid01.jpg|Bullous pemphigoid. <SMALL><SMALL>''[http://www.atlasdermatologico.com.br/  With permission from Dermatology Atlas.]''<ref name="Dermatology Atlas">{{Cite web | title = Dermatology Atlas | url = http://www.atlasdermatologico.com.br/}}</ref></SMALL></SMALL>


Image:Bullous pemphigoid02.jpg|Bullous pemphigoid. <SMALL><SMALL>''[http://www.atlasdermatologico.com.br/  Permission from Dermatology Atlas.]''<ref name="Dermatology Atlas">{{Cite web | title = Dermatology Atlas | url = http://www.atlasdermatologico.com.br/}}</ref></SMALL></SMALL>
Image:Bullous pemphigoid02.jpg|Bullous pemphigoid. <SMALL><SMALL>''[http://www.atlasdermatologico.com.br/  With permission from Dermatology Atlas.]''<ref name="Dermatology Atlas">{{Cite web | title = Dermatology Atlas | url = http://www.atlasdermatologico.com.br/}}</ref></SMALL></SMALL>




Image:Bullous pemphigoid03.jpg|Bullous pemphigoid. <SMALL><SMALL>''[http://www.atlasdermatologico.com.br/  Permission from Dermatology Atlas.]''<ref name="Dermatology Atlas">{{Cite web | title = Dermatology Atlas | url = http://www.atlasdermatologico.com.br/}}</ref></SMALL></SMALL>
Image:Bullous pemphigoid03.jpg|Bullous pemphigoid. <SMALL><SMALL>''[http://www.atlasdermatologico.com.br/  With permission from Dermatology Atlas.]''<ref name="Dermatology Atlas">{{Cite web | title = Dermatology Atlas | url = http://www.atlasdermatologico.com.br/}}</ref></SMALL></SMALL>


Image:Bullous pemphigoid04.jpg|Bullous pemphigoid. <SMALL><SMALL>''[http://www.atlasdermatologico.com.br/  Permission from Dermatology Atlas.]''<ref name="Dermatology Atlas">{{Cite web | title = Dermatology Atlas | url = http://www.atlasdermatologico.com.br/}}</ref></SMALL></SMALL>
Image:Bullous pemphigoid04.jpg|Bullous pemphigoid. <SMALL><SMALL>''[http://www.atlasdermatologico.com.br/  With permission from Dermatology Atlas.]''<ref name="Dermatology Atlas">{{Cite web | title = Dermatology Atlas | url = http://www.atlasdermatologico.com.br/}}</ref></SMALL></SMALL>


Image:Bullous pemphigoid05.jpg|Bullous pemphigoid. <SMALL><SMALL>''[http://www.atlasdermatologico.com.br/  Permission from Dermatology Atlas.]''<ref name="Dermatology Atlas">{{Cite web | title = Dermatology Atlas | url = http://www.atlasdermatologico.com.br/}}</ref></SMALL></SMALL>
Image:Bullous pemphigoid05.jpg|Bullous pemphigoid. <SMALL><SMALL>''[http://www.atlasdermatologico.com.br/  With permission from Dermatology Atlas.]''<ref name="Dermatology Atlas">{{Cite web | title = Dermatology Atlas | url = http://www.atlasdermatologico.com.br/}}</ref></SMALL></SMALL>
Image:Bullous pemphigoid06.jpg|Bullous pemphigoid. <SMALL><SMALL>''[http://www.atlasdermatologico.com.br/  Permission from Dermatology Atlas.]''<ref name="Dermatology Atlas">{{Cite web | title = Dermatology Atlas | url = http://www.atlasdermatologico.com.br/}}</ref></SMALL></SMALL>
Image:Bullous pemphigoid06.jpg|Bullous pemphigoid. <SMALL><SMALL>''[http://www.atlasdermatologico.com.br/  With permission from Dermatology Atlas.]''<ref name="Dermatology Atlas">{{Cite web | title = Dermatology Atlas | url = http://www.atlasdermatologico.com.br/}}</ref></SMALL></SMALL>


Image:Bullous pemphigoid07.jpg|Bullous pemphigoid. <SMALL><SMALL>''[http://www.atlasdermatologico.com.br/  Permission from Dermatology Atlas.]''<ref name="Dermatology Atlas">{{Cite web | title = Dermatology Atlas | url = http://www.atlasdermatologico.com.br/}}</ref></SMALL></SMALL>
Image:Bullous pemphigoid07.jpg|Bullous pemphigoid. <SMALL><SMALL>''[http://www.atlasdermatologico.com.br/  With permission from Dermatology Atlas.]''<ref name="Dermatology Atlas">{{Cite web | title = Dermatology Atlas | url = http://www.atlasdermatologico.com.br/}}</ref></SMALL></SMALL>
Image:Bullous pemphigoid09.jpg|Bullous pemphigoid. <SMALL><SMALL>''[http://www.atlasdermatologico.com.br/  Permission from Dermatology Atlas.]''<ref name="Dermatology Atlas">{{Cite web | title = Dermatology Atlas | url = http://www.atlasdermatologico.com.br/}}</ref></SMALL></SMALL>
Image:Bullous pemphigoid09.jpg|Bullous pemphigoid. <SMALL><SMALL>''[http://www.atlasdermatologico.com.br/  With permission from Dermatology Atlas.]''<ref name="Dermatology Atlas">{{Cite web | title = Dermatology Atlas | url = http://www.atlasdermatologico.com.br/}}</ref></SMALL></SMALL>


Image:Bullous pemphigoid10.jpg|Bullous pemphigoid. <SMALL><SMALL>''[http://www.atlasdermatologico.com.br/  Permission from Dermatology Atlas.]''<ref name="Dermatology Atlas">{{Cite web | title = Dermatology Atlas | url = http://www.atlasdermatologico.com.br/}}</ref></SMALL></SMALL>
Image:Bullous pemphigoid10.jpg|Bullous pemphigoid. <SMALL><SMALL>''[http://www.atlasdermatologico.com.br/  With permission from Dermatology Atlas.]''<ref name="Dermatology Atlas">{{Cite web | title = Dermatology Atlas | url = http://www.atlasdermatologico.com.br/}}</ref></SMALL></SMALL>
Image:Bullous pemphigoid11.jpg|Bullous pemphigoid. <SMALL><SMALL>''[http://www.atlasdermatologico.com.br/  Permission from Dermatology Atlas.]''<ref name="Dermatology Atlas">{{Cite web | title = Dermatology Atlas | url = http://www.atlasdermatologico.com.br/}}</ref></SMALL></SMALL>
Image:Bullous pemphigoid11.jpg|Bullous pemphigoid. <SMALL><SMALL>''[http://www.atlasdermatologico.com.br/  With permission from Dermatology Atlas.]''<ref name="Dermatology Atlas">{{Cite web | title = Dermatology Atlas | url = http://www.atlasdermatologico.com.br/}}</ref></SMALL></SMALL>
Image:Bullous pemphigoid12.jpg|Bullous pemphigoid. <SMALL><SMALL>''[http://www.atlasdermatologico.com.br/  Permission from Dermatology Atlas.]''<ref name="Dermatology Atlas">{{Cite web | title = Dermatology Atlas | url = http://www.atlasdermatologico.com.br/}}</ref></SMALL></SMALL>
Image:Bullous pemphigoid12.jpg|Bullous pemphigoid. <SMALL><SMALL>''[http://www.atlasdermatologico.com.br/  With permission from Dermatology Atlas.]''<ref name="Dermatology Atlas">{{Cite web | title = Dermatology Atlas | url = http://www.atlasdermatologico.com.br/}}</ref></SMALL></SMALL>


Image:Bullous pemphigoid13.jpg|Bullous pemphigoid. <SMALL><SMALL>''[http://www.atlasdermatologico.com.br/  Permission from Dermatology Atlas.]''<ref name="Dermatology Atlas">{{Cite web | title = Dermatology Atlas | url = http://www.atlasdermatologico.com.br/}}</ref></SMALL></SMALL>
Image:Bullous pemphigoid13.jpg|Bullous pemphigoid. <SMALL><SMALL>''[http://www.atlasdermatologico.com.br/  With permission from Dermatology Atlas.]''<ref name="Dermatology Atlas">{{Cite web | title = Dermatology Atlas | url = http://www.atlasdermatologico.com.br/}}</ref></SMALL></SMALL>






Image:Bullous pemphigoid14.jpg|Bullous pemphigoid. <SMALL><SMALL>''[http://www.atlasdermatologico.com.br/  Permission from Dermatology Atlas.]''<ref name="Dermatology Atlas">{{Cite web | title = Dermatology Atlas | url = http://www.atlasdermatologico.com.br/}}</ref></SMALL></SMALL>
Image:Bullous pemphigoid14.jpg|Bullous pemphigoid. <SMALL><SMALL>''[http://www.atlasdermatologico.com.br/  With permission from Dermatology Atlas.]''<ref name="Dermatology Atlas">{{Cite web | title = Dermatology Atlas | url = http://www.atlasdermatologico.com.br/}}</ref></SMALL></SMALL>


Image:Bullous pemphigoid16.jpg|Bullous pemphigoid. <SMALL><SMALL>''[http://www.atlasdermatologico.com.br/  Permission from Dermatology Atlas.]''<ref name="Dermatology Atlas">{{Cite web | title = Dermatology Atlas | url = http://www.atlasdermatologico.com.br/}}</ref></SMALL></SMALL>
Image:Bullous pemphigoid16.jpg|Bullous pemphigoid. <SMALL><SMALL>''[http://www.atlasdermatologico.com.br/  With permission from Dermatology Atlas.]''<ref name="Dermatology Atlas">{{Cite web | title = Dermatology Atlas | url = http://www.atlasdermatologico.com.br/}}</ref></SMALL></SMALL>






Image:Bullous pemphigoid17.jpg|Bullous pemphigoid. <SMALL><SMALL>''[http://www.atlasdermatologico.com.br/  Permission from Dermatology Atlas.]''<ref name="Dermatology Atlas">{{Cite web | title = Dermatology Atlas | url = http://www.atlasdermatologico.com.br/}}</ref></SMALL></SMALL>
Image:Bullous pemphigoid17.jpg|Bullous pemphigoid. <SMALL><SMALL>''[http://www.atlasdermatologico.com.br/  With permission from Dermatology Atlas.]''<ref name="Dermatology Atlas">{{Cite web | title = Dermatology Atlas | url = http://www.atlasdermatologico.com.br/}}</ref></SMALL></SMALL>




Image:Bullous pemphigoid19.jpg|Bullous pemphigoid. <SMALL><SMALL>''[http://www.atlasdermatologico.com.br/  Permission from Dermatology Atlas.]''<ref name="Dermatology Atlas">{{Cite web | title = Dermatology Atlas | url = http://www.atlasdermatologico.com.br/}}</ref></SMALL></SMALL>
Image:Bullous pemphigoid19.jpg|Bullous pemphigoid. <SMALL><SMALL>''[http://www.atlasdermatologico.com.br/  With permission from Dermatology Atlas.]''<ref name="Dermatology Atlas">{{Cite web | title = Dermatology Atlas | url = http://www.atlasdermatologico.com.br/}}</ref></SMALL></SMALL>


Image:Bullous pemphigoid20.jpg|Bullous pemphigoid. <SMALL><SMALL>''[http://www.atlasdermatologico.com.br/  Permission from Dermatology Atlas.]''<ref name="Dermatology Atlas">{{Cite web | title = Dermatology Atlas | url = http://www.atlasdermatologico.com.br/}}</ref></SMALL></SMALL>
Image:Bullous pemphigoid20.jpg|Bullous pemphigoid. <SMALL><SMALL>''[http://www.atlasdermatologico.com.br/  With permission from Dermatology Atlas.]''<ref name="Dermatology Atlas">{{Cite web | title = Dermatology Atlas | url = http://www.atlasdermatologico.com.br/}}</ref></SMALL></SMALL>
Image:Bullous pemphigoid21.jpg|Bullous pemphigoid. <SMALL><SMALL>''[http://www.atlasdermatologico.com.br/  Permission from Dermatology Atlas.]''<ref name="Dermatology Atlas">{{Cite web | title = Dermatology Atlas | url = http://www.atlasdermatologico.com.br/}}</ref></SMALL></SMALL>
Image:Bullous pemphigoid21.jpg|Bullous pemphigoid. <SMALL><SMALL>''[http://www.atlasdermatologico.com.br/  With permission from Dermatology Atlas.]''<ref name="Dermatology Atlas">{{Cite web | title = Dermatology Atlas | url = http://www.atlasdermatologico.com.br/}}</ref></SMALL></SMALL>
Image:Bullous pemphigoid22.jpg|Bullous pemphigoid. <SMALL><SMALL>''[http://www.atlasdermatologico.com.br/  Permission from Dermatology Atlas.]''<ref name="Dermatology Atlas">{{Cite web | title = Dermatology Atlas | url = http://www.atlasdermatologico.com.br/}}</ref></SMALL></SMALL>
Image:Bullous pemphigoid22.jpg|Bullous pemphigoid. <SMALL><SMALL>''[http://www.atlasdermatologico.com.br/  With permission from Dermatology Atlas.]''<ref name="Dermatology Atlas">{{Cite web | title = Dermatology Atlas | url = http://www.atlasdermatologico.com.br/}}</ref></SMALL></SMALL>


Image:Bullous pemphigoid23.jpg|Bullous pemphigoid. <SMALL><SMALL>''[http://www.atlasdermatologico.com.br/  Permission from Dermatology Atlas.]''<ref name="Dermatology Atlas">{{Cite web | title = Dermatology Atlas | url = http://www.atlasdermatologico.com.br/}}</ref></SMALL></SMALL>
Image:Bullous pemphigoid23.jpg|Bullous pemphigoid. <SMALL><SMALL>''[http://www.atlasdermatologico.com.br/  With permission from Dermatology Atlas.]''<ref name="Dermatology Atlas">{{Cite web | title = Dermatology Atlas | url = http://www.atlasdermatologico.com.br/}}</ref></SMALL></SMALL>




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<gallery>
<gallery>


Image:Bullous pemphigoid04.jpg|Bullous pemphigoid. <SMALL><SMALL>''[http://www.atlasdermatologico.com.br/  Permission from Dermatology Atlas.]''<ref name="Dermatology Atlas">{{Cite web | title = Dermatology Atlas | url = http://www.atlasdermatologico.com.br/}}</ref></SMALL></SMALL>
Image:Bullous pemphigoid04.jpg|Bullous pemphigoid. <SMALL><SMALL>''[http://www.atlasdermatologico.com.br/  With permission from Dermatology Atlas.]''<ref name="Dermatology Atlas">{{Cite web | title = Dermatology Atlas | url = http://www.atlasdermatologico.com.br/}}</ref></SMALL></SMALL>




Image:Bullous pemphigoid08.jpg|Bullous pemphigoid. <SMALL><SMALL>''[http://www.atlasdermatologico.com.br/  Permission from Dermatology Atlas.]''<ref name="Dermatology Atlas">{{Cite web | title = Dermatology Atlas | url = http://www.atlasdermatologico.com.br/}}</ref></SMALL></SMALL>
Image:Bullous pemphigoid08.jpg|Bullous pemphigoid. <SMALL><SMALL>''[http://www.atlasdermatologico.com.br/  With permission from Dermatology Atlas.]''<ref name="Dermatology Atlas">{{Cite web | title = Dermatology Atlas | url = http://www.atlasdermatologico.com.br/}}</ref></SMALL></SMALL>


Image:Bullous pemphigoid15.jpg|Bullous pemphigoid. <SMALL><SMALL>''[http://www.atlasdermatologico.com.br/  Permission from Dermatology Atlas.]''<ref name="Dermatology Atlas">{{Cite web | title = Dermatology Atlas | url = http://www.atlasdermatologico.com.br/}}</ref></SMALL></SMALL>
Image:Bullous pemphigoid15.jpg|Bullous pemphigoid. <SMALL><SMALL>''[http://www.atlasdermatologico.com.br/  With permission from Dermatology Atlas.]''<ref name="Dermatology Atlas">{{Cite web | title = Dermatology Atlas | url = http://www.atlasdermatologico.com.br/}}</ref></SMALL></SMALL>




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=====Face=====
=====Face=====
<gallery>
<gallery>
Image:Bullous pemphigoid18.jpg|Bullous pemphigoid. <SMALL><SMALL>''[http://www.atlasdermatologico.com.br/  Permission from Dermatology Atlas.]''<ref name="Dermatology Atlas">{{Cite web | title = Dermatology Atlas | url = http://www.atlasdermatologico.com.br/}}</ref></SMALL></SMALL>
Image:Bullous pemphigoid18.jpg|Bullous pemphigoid. <SMALL><SMALL>''[http://www.atlasdermatologico.com.br/  With permission from Dermatology Atlas.]''<ref name="Dermatology Atlas">{{Cite web | title = Dermatology Atlas | url = http://www.atlasdermatologico.com.br/}}</ref></SMALL></SMALL>




</gallery>
</gallery>


==Differentiating Bullous pemphigoid from other diseases==
===Laboratory Findings===
 
===Imaging Findings===
 
===Other Diagnostic Studies===
 
==Treatment==
 
===Medical Therapy===
 
===Surgery===


===Prevention===


==See also==
==See also==
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[[Category:Autoimmune diseases]]
[[Category:Autoimmune diseases]]
[[Category:Dermatology]]
[[Category:Dermatology]]
<br>
<br/>


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Latest revision as of 14:29, 10 June 2016

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1];Associate Editor(s)-in-Chief: Kiran Singh, M.D. [2]

Overview

Bullous pemphigoid, also referred to as BP, is a chronic autoimmune skin disease, involving the formation of blisters below the surface of the skin and antibodies against the type XVII collagen component of hemidesmosomes. It can also (albeit only rarely) involve the mucous membranes, and has been shown to afflict dogs, cats, pigs, and horses, as well as humans.

Historical Perspective

Classification

Pathophysiology

Causes

Differentiating Bullous Pemphigoid from Other Diseases

Epidemiology and Demographics

Age

Gender

Race

Risk Factors

Natural History, Complications and Prognosis

Diagnosis

Diagnostic Criteria

Symptoms

Physical Examination

Skin

Extremity
Trunk
Face

Laboratory Findings

Imaging Findings

Other Diagnostic Studies

Treatment

Medical Therapy

Surgery

Prevention

See also

External links


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  1. 1.00 1.01 1.02 1.03 1.04 1.05 1.06 1.07 1.08 1.09 1.10 1.11 1.12 1.13 1.14 1.15 1.16 1.17 1.18 1.19 1.20 1.21 1.22 1.23 "Dermatology Atlas".