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{{Buerger's disease}}
{{Buerger's disease}}
{{CMG}};{{AE}}{{HM}}
{{CMG}};{{AE}}{{HM}}
==Other Imaging Findings==


==Overview==
==Overview==
There are no other imaging findings associated with [disease name].
Buerger's disease is diagnosed mostly clinically, however, in cases where diagnosis is indefinite and the extent of disease is unknown, a catheter-based arteriogram may be helpful in the diagnosis of Buerger's disease. Findings on a catheter-based arteriogram suggestive of Buerger's disease include the absence of [[atherosclerosis]], lack of a source for [[thromboembolism]], small and medium-sized vessel involvement, segmental affection of vessels between normal appearing segments, and corkscrew collaterals described as collateralizations around an occlusion area, however, this finding is not [[pathognomonic]].  
 
OR
 
[Imaging modality] may be helpful in the diagnosis of [disease name]. Findings on an [imaging modality] suggestive of/diagnostic of [disease name] include [finding 1], [finding 2], and [finding 3].


==Other Imaging Findings==
==Other Imaging Findings==
*There are no other imaging findings associated with [disease name].
*Catheter-based arteriogram is able to detect early signs of vascular damage.<ref name="pmid16722538">{{cite journal |vauthors=Arkkila PE |title=Thromboangiitis obliterans (Buerger's disease) |journal=Orphanet J Rare Dis |volume=1 |issue= |pages=14 |date=April 2006 |pmid=16722538 |pmc=1523324 |doi=10.1186/1750-1172-1-14 |url=}}</ref><ref name="pmid22784658">{{cite journal |vauthors=Dimmick SJ, Goh AC, Cauzza E, Steinbach LS, Baumgartner I, Stauffer E, Voegelin E, Anderson SE |title=Imaging appearances of Buerger's disease complications in the upper and lower limbs |journal=Clin Radiol |volume=67 |issue=12 |pages=1207–11 |date=December 2012 |pmid=22784658 |doi=10.1016/j.crad.2012.04.005 |url=}}</ref><ref name="pmid5431503">{{cite journal |vauthors=Lambeth JT, Yong NK |title=Arteriographic findings in thromboangiitis obliterans with emphasis on femoropopliteal involvement |journal=Am J Roentgenol Radium Ther Nucl Med |volume=109 |issue=3 |pages=553–62 |date=July 1970 |pmid=5431503 |doi= |url=}}</ref><ref name="pmid19536378">{{cite journal |vauthors=Yoshimuta T, Akutsu K, Okajima T, Tamori Y, Kubota Y, Takeshita S |title=Corkscrew collaterals in Buerger's disease |journal=Can J Cardiol |volume=25 |issue=6 |pages=365 |date=June 2009 |pmid=19536378 |pmc=2722480 |doi= |url=}}</ref>
 
*A dye is injected into an artery and serial x-rays are taken.
*[Imaging modality] may be helpful in the diagnosis of [disease name]. Findings on an [imaging modality] suggestive of/diagnostic of [disease name] include:
*The following result of catheter-based arteriogram is confirmatory of Buerger disease:
**[Finding 1]
**Absence of [[atherosclerosis]]
**[Finding 2]
**No cause for [[thromboembolism]]
**[Finding 3]
**Small and medium-sized vessels involved, namely [[Tibial artery|tibial]], [[Popliteal artery|popliteal]], and [[Radial artery|radial]] arteries
 
**Segmental affection/bloackage of vessels between normal appearing segments
===Angiogram===
**Corkscrew collaterals described as collateralization around occlusion area but are not pathognomonic
This test can detect early signs of vessel damage and help the doctor know the condition of your arteries. During the procedure, the dye is injected into an artery and then take X-rays image. On images, patients with buerger's disease may show signs of blockages in the artery.
 
DIAGNOSIS — Thromboangiitis obliterans is a predominantly clinical diagnosis that should be suspected in young patients who smoke and who present with ischemia of the hands and/or feet. However, the diagnosis of thromboangiitis obliterans may be a diagnosis of exclusion after ruling out other more common entities which may produce similar clinical symptoms. Biopsy provides a definitive diagnosis, but subcutaneous nodules are not always present. A clinical diagnosis can be established based upon a scoring system using clinical, angiographic, histopathological, and exclusionary criteria [5,62].
 
Thromboangiitis obliterans is differentiated from other entities that cause vascular occlusive disease (table 1), the most common of which are discussed below:
 
●Atherosclerotic peripheral artery disease – The distal nature of thromboangiitis obliterans and involvement of the lower and upper extremities helps to distinguish the disorder from atherosclerosis. Other risk factors for peripheral artery disease, such as hypertension and hypercholesterolemia, may be absent. In the absence of a histological diagnosis of the acute phase lesion, a diagnosis of diabetes mellitus excludes thromboangiitis obliterans.
 
●Thromboembolic disease – Patients with thromboangiitis obliterans will not have a proximal source for embolism (cardiac, aneurysmal disease) or laboratory evidence of a thrombophilia, though anticardiolipin antibodies may be present.
 
●Vasculitis – Although distal vessel involvement causes distal ischemia in other vasculitides, serologic markers are negative in thromboangiitis obliterans.
 
●Repetitive trauma – These patients have an occupational history (eg, jackhammer operator) to suggest the mechanism of small vessel disease.
 
Clinical criteria — A clinical diagnosis can be established with the following commonly used criteria [55,56,63]:
 
●Age less than 45 years
 
●Current or recent history of tobacco use


●Distal extremity ischemia (objectively noted on vascular testing) (See 'Vascular evaluation' above.)


●Typical arteriographic findings of thromboangiitis obliterans (See 'Imaging studies' above.)


●Exclusion of autoimmune disease, thrombophilia, diabetes, and proximal embolic sources (table 1)





Revision as of 14:13, 12 April 2018

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1];Associate Editor(s)-in-Chief: Hadeel Maksoud M.D.[2]

Overview

Buerger's disease is diagnosed mostly clinically, however, in cases where diagnosis is indefinite and the extent of disease is unknown, a catheter-based arteriogram may be helpful in the diagnosis of Buerger's disease. Findings on a catheter-based arteriogram suggestive of Buerger's disease include the absence of atherosclerosis, lack of a source for thromboembolism, small and medium-sized vessel involvement, segmental affection of vessels between normal appearing segments, and corkscrew collaterals described as collateralizations around an occlusion area, however, this finding is not pathognomonic.

Other Imaging Findings

  • Catheter-based arteriogram is able to detect early signs of vascular damage.[1][2][3][4]
  • A dye is injected into an artery and serial x-rays are taken.
  • The following result of catheter-based arteriogram is confirmatory of Buerger disease:
    • Absence of atherosclerosis
    • No cause for thromboembolism
    • Small and medium-sized vessels involved, namely tibial, popliteal, and radial arteries
    • Segmental affection/bloackage of vessels between normal appearing segments
    • Corkscrew collaterals described as collateralization around occlusion area but are not pathognomonic



References

  1. Arkkila PE (April 2006). "Thromboangiitis obliterans (Buerger's disease)". Orphanet J Rare Dis. 1: 14. doi:10.1186/1750-1172-1-14. PMC 1523324. PMID 16722538.
  2. Dimmick SJ, Goh AC, Cauzza E, Steinbach LS, Baumgartner I, Stauffer E, Voegelin E, Anderson SE (December 2012). "Imaging appearances of Buerger's disease complications in the upper and lower limbs". Clin Radiol. 67 (12): 1207–11. doi:10.1016/j.crad.2012.04.005. PMID 22784658.
  3. Lambeth JT, Yong NK (July 1970). "Arteriographic findings in thromboangiitis obliterans with emphasis on femoropopliteal involvement". Am J Roentgenol Radium Ther Nucl Med. 109 (3): 553–62. PMID 5431503.
  4. Yoshimuta T, Akutsu K, Okajima T, Tamori Y, Kubota Y, Takeshita S (June 2009). "Corkscrew collaterals in Buerger's disease". Can J Cardiol. 25 (6): 365. PMC 2722480. PMID 19536378.

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