Buerger's disease natural history, complications and prognosis

Jump to navigation Jump to search

Buerger's disease Microchapters

Home

Patient Information

Overview

Historical Perspective

Classification

Pathophysiology

Causes

Differentiating Buerger's Disease from other Diseases

Epidemiology and Demographics

Risk Factors

Screening

Natural History, Complications and Prognosis

Diagnosis

Diagnostic Study of Choice

History and Symptoms

Physical Examination

Laboratory Findings

Electrocardiogram

X-ray

Echocardiography and Ultrasound

CT scan

MRI

Other Imaging Findings

Other Diagnostic Studies

Treatment

Medical Therapy

Surgery

Primary Prevention

Secondary Prevention

Cost-Effectiveness of Therapy

Future or Investigational Therapies

Case Studies

Case #1

Buerger's disease natural history, complications and prognosis On the Web

Most recent articles

Most cited articles

Review articles

CME Programs

Powerpoint slides

Images

American Roentgen Ray Society Images of Buerger's disease natural history, complications and prognosis

All Images
X-rays
Echo & Ultrasound
CT Images
MRI

Ongoing Trials at Clinical Trials.gov

US National Guidelines Clearinghouse

NICE Guidance

FDA on Buerger's disease natural history, complications and prognosis

CDC on Buerger's disease natural history, complications and prognosis

Buerger's disease natural history, complications and prognosis in the news

Blogs on Buerger's disease natural history, complications and prognosis

Directions to Hospitals Treating Buerger's disease

Risk calculators and risk factors for Buerger's disease natural history, complications and prognosis

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1];Associate Editor(s)-in-Chief: Hadeel Maksoud M.D.[2]

Overview

If left untreated, 75% of patients with Buerger's disease may have a relapsing and remitting course, whilst 20% may progress and 5% may have a benign course of Buerger's disease. Common complications of Buerger disease include amputation, gangrene and loss of circulation beyond the affected hand or foot. Smoking cessation leads to an 8-fold decrease in the risk for amputation. Amputation is common and more severe in patients who continue to use tobacco, which often leads to vascular insufficiency. Buerger's disease is rarely immediately fatal, but rather a life shortening disease. Prognosis of Buerger's disease varies from person to person, depending on the patient's life-style and the severity of the damaged vessels.

Natural History, Complications, and Prognosis

Natural History

  • The symptoms of Buerger disease usually develop in the third to forth decade of life, and start with symptoms such as pallor and ischemia of the extremities.[1][2]
  • If left untreated, approximately 75% of patients with Buerger's disease may have a relapsing and remitting course, whilst 20% may progress and 5% may have a benign course of Buerger's disease.

Complications

Prognosis

  • Smoking cessation leads to an 8-fold decrease in the risk for amputation.[1][2]
  • Amputation is common and more severe in patients who continue to use tobacco, which often leads to vascular insufficiency.
  • Buerger's disease is rarely immediately fatal, but rather a life shortening disease.
  • Prognosis of Buerger's disease varies from person to person, depending on:
    • The patient's life-style
    • The severity of the damaged vessels

References

  1. 1.0 1.1 1.2 Ohta T, Ishioashi H, Hosaka M, Sugimoto I (January 2004). "Clinical and social consequences of Buerger disease". J. Vasc. Surg. 39 (1): 176–80. doi:10.1016/j.jvs.2003.08.006. PMID 14718836.
  2. 2.0 2.1 2.2 Cooper LT, Tse TS, Mikhail MA, McBane RD, Stanson AW, Ballman KV (December 2004). "Long-term survival and amputation risk in thromboangiitis obliterans (Buerger's disease)". J. Am. Coll. Cardiol. 44 (12): 2410–1. doi:10.1016/j.jacc.2004.09.029. PMID 15607407.

Template:WH Template:WS