Buerger's disease laboratory findings: Difference between revisions

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==Overview==
==Overview==
An elevated/reduced concentration of serum/blood/urinary/CSF/other [lab test] is diagnostic of [disease name].
There are no diagnostic laboratory findings associated with Buerger's disease. Lab testing is done to exclude other vasculitides, such as lupus, scleroderma and mixed connective tissue disease.  
 
OR
 
Laboratory findings consistent with the diagnosis of [disease name] include [abnormal test 1], [abnormal test 2], and [abnormal test 3].
 
OR
 
[Test] is usually normal for patients with [disease name].
 
OR
 
Some patients with [disease name] may have elevated/reduced concentration of [test], which is usually suggestive of [progression/complication].
 
OR
 
There are no diagnostic laboratory findings associated with [disease name].


==Laboratory Findings==
==Laboratory Findings==
 
*There are no diagnostic laboratory findings associated with Buerger's disease.<ref name="pmid20421527">{{cite journal |vauthors=Piazza G, Creager MA |title=Thromboangiitis obliterans |journal=Circulation |volume=121 |issue=16 |pages=1858–61 |date=April 2010 |pmid=20421527 |pmc=2880529 |doi=10.1161/CIRCULATIONAHA.110.942383 |url=}}</ref><ref name="pmid10995867">{{cite journal |vauthors=Olin JW |title=Thromboangiitis obliterans (Buerger's disease) |journal=N. Engl. J. Med. |volume=343 |issue=12 |pages=864–9 |date=September 2000 |pmid=10995867 |doi=10.1056/NEJM200009213431207 |url=}}</ref>
*There are no diagnostic laboratory findings associated with [disease name].
*Laboratory testing is performed to exclude other pathologies, and include:
OR
**Acute phase reactants that indicate an active inflammatory process:
*An elevated/reduced concentration of serum/blood/urinary/CSF/other [lab test] is diagnostic of [disease name].
***[[Erythrocyte sedimentation rate]]  
*[Test] is usually normal among patients with [disease name].
***[[C-reactive protein]]
*Laboratory findings consistent with the diagnosis of [disease name] include:
**Immunologic panel to rule out autoimmune disease:
**[Abnormal test 1]
***[[Antinuclear antibody]]
**[Abnormal test 2]
***[[Rheumatoid factor]]
**[Abnormal test 3]
***Anticentromere antibody
 
***[[Antiphospholipid antibodY]]
*Some patients with [disease name] may have elevated/reduced concentration of [test], which is usually suggestive of [progression/complication].
***Serum [[creatinine]]
 
***Complement
Blood tests, including [[complete blood count]], [[glucose]], [[liver function]] test, serum [[creatinine]] determination, [[erythrocyte sedimentation rate]], [[C-reactive protein]], [[antinuclear antibody]], [[rheumatoid factor]], anticentromere antibody, [[antiphospholipid antibodies]] may help rule out diseases such as [[diabetes]], [[scleroderma]], [[systemic lupus erythematosus]] and other disorders.
***SCL-70
**To rule out hypercoagulability:
***[[Complete blood count]]
***[[Liver function]] test
***PT, PTT and INR
***Antiphospholipid antibodies
***Anticardiolipin antibodies
***Protein C and S
***Antithrombin III
***Factor V Leiden
***Prothrombin gene mutation
**Toxicology screen
***Cocaine
***Amphetamine
***Cannabis




Revision as of 18:36, 11 April 2018

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1];Associate Editor(s)-in-Chief: Hadeel Maksoud M.D.[2]

Overview

There are no diagnostic laboratory findings associated with Buerger's disease. Lab testing is done to exclude other vasculitides, such as lupus, scleroderma and mixed connective tissue disease.

Laboratory Findings


References

  1. ↑ Piazza G, Creager MA (April 2010). "Thromboangiitis obliterans". Circulation. 121 (16): 1858–61. doi:10.1161/CIRCULATIONAHA.110.942383. PMC 2880529. PMID 20421527.
  2. ↑ Olin JW (September 2000). "Thromboangiitis obliterans (Buerger's disease)". N. Engl. J. Med. 343 (12): 864–9. doi:10.1056/NEJM200009213431207. PMID 10995867.

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