Bone or cartilage mass classification: Difference between revisions
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Bone and cartilage tumors may be classified by location, origin, and histopahological origin. | Bone and cartilage tumors may be classified by location, origin, and histopahological origin. | ||
* '''Tumor location''' | * '''Tumor location''' | ||
:*Diaphysis | :*[[Diaphysis]] | ||
:*Epiphysis | :*[[Epiphysis]] | ||
:*Metaphysis | :*[[Metaphysis]] | ||
:*Other/Unclassifed | :*Other/Unclassifed | ||
* '''Tumor nature''' | * '''Tumor nature''' | ||
| Line 20: | Line 20: | ||
* '''Origin''' | * '''Origin''' | ||
:*Primary | :*Primary | ||
:*Secondary ( see "Secondary tumors classification" | :*Secondary ( see "Secondary tumors classification" below) | ||
* '''Histopathological origin''' | * '''Histopathological origin''' | ||
:*Cartilage tumors | :*Cartilage tumors | ||
| Line 46: | Line 46: | ||
|- | |- | ||
| style="text-align: left;" | | | style="text-align: left;" | | ||
*Osteoid osteoma | *[[Osteoid osteoma]] | ||
*Osteoblastoma | *[[Osteoblastoma]] | ||
*Osteoma | *[[Osteoma]] | ||
*Osteosarcoma | *[[Osteosarcoma]] | ||
| style="text-align: left;" | | | style="text-align: left;" | | ||
*Osteochondroma | *[[Osteochondroma]] | ||
*Chondroblastoma | *[[Chondroblastoma]] | ||
*Enchondroma | *[[Enchondroma]] | ||
*Chondromyxoid fibroma | *[[Chondromyxoid fibroma]] | ||
| style="text-align: left;" | | | style="text-align: left;" | | ||
*Desmoplastic fibroma | *[[Desmoplastic fibroma]] | ||
*Fibrous dysplasia | *[[Fibrous dysplasia]] | ||
*Ossyifing fibroma | *[[Ossyifing fibroma]] | ||
*Non-ossifying fibroma | *[[Non-ossifying fibroma]] | ||
| style="text-align: left;" | | | style="text-align: left;" | | ||
*Unicameral bone cyst | *[[Unicameral bone cyst]] | ||
*Aneurysmal bone cyst | *Aneurysmal [[bone cyst]] | ||
| style="text-align: left;" | | | style="text-align: left;" | | ||
*Giant cell tumor | *[[Giant cell tumor]] | ||
*Adamantimoma | *[[Adamantimoma]] | ||
*Eosinophilic granuloma | *[[Eosinophilic granuloma]] | ||
*Ewing sarcoma | *[[Ewing sarcoma]] | ||
*Metastases | *[[Metastases]] | ||
|- | |- | ||
!style="background: #4479BA; width: 300px;" colspan=2|{{fontcolor|#FFF|Epiphysis}} | !style="background: #4479BA; width: 300px;" colspan=2|{{fontcolor|#FFF|Epiphysis}} | ||
| Line 77: | Line 77: | ||
|- | |- | ||
| style="text-align: left;"colspan=2 | | | style="text-align: left;"colspan=2 | | ||
*Chondroblastoma | *[[Chondroblastoma]] | ||
*Giant cell tumor | *[[Giant cell tumor]] | ||
*Intraosseous ganglion | *[[Intraosseous ganglion]] | ||
*Chondrosarcoma | *[[Chondrosarcoma]] | ||
*Metastases | *[[Metastases]] | ||
*Ewing | *[[Ewing sarcoma]] | ||
| style="text-align: left;"colspan=2 | | | style="text-align: left;"colspan=2 | | ||
| style="text-align: left;"colspan=2 | | | style="text-align: left;"colspan=2 | | ||
*Eosinophilic granuloma | *[[Eosinophilic granuloma]] | ||
*Ewing sarcoma | *[[Ewing sarcoma]]ada | ||
*Myeloma | *[[Myeloma]] | ||
*Metastases | *[[Metastases]] | ||
* | *[[Adamantinoma]] | ||
*Ossyfing fibroma | *[[Ossyfing fibroma]] | ||
*Enchondroma | *[[Enchondroma]] | ||
| style="text-align: lwdr;" colspan=2| | | style="text-align: lwdr;" colspan=2| | ||
*Osteosarcoma | *[[Osteosarcoma]] | ||
*Chondromyxoid fibroma | *[[Chondromyxoid fibroma]] | ||
*Unicameral bone cyst | *[[Unicameral bone cyst]] | ||
*Osteoid osteoma | *[[Osteoid osteoma]] | ||
*Metastases | *[[Metastases]] | ||
|- | |- | ||
!style="background: #4479BA; width: 300px;" colspan=3|{{fontcolor|#FFF|Benign}} | !style="background: #4479BA; width: 300px;" colspan=3|{{fontcolor|#FFF|Benign}} | ||
| Line 106: | Line 106: | ||
|- | |- | ||
| style="text-align: left;" colspan=3 | | | style="text-align: left;" colspan=3 | | ||
*Osteoid osteoma | *[[Osteoid osteoma]] | ||
*Enchondroma | *[[Enchondroma]] | ||
*Chondromyxoid fibroma | *[[Chondromyxoid fibroma]] | ||
*Ossifying fibroma | *[[Ossifying fibroma]] | ||
*Osteoblastoma | *[[Osteoblastoma]] | ||
*Unicameral bone cyst | *[[Unicameral bone cyst]] | ||
*Aneursymal bone cyst | * Aneursymal[[bone cyst]] | ||
*Giant cell tumor | *[[Giant cell tumor]] | ||
*Osteochondroma | *[[Osteochondroma]] | ||
| style="text-align: left;" colspan=2 | | | style="text-align: left;" colspan=2 | | ||
*Osteosarcoma | *[[Osteosarcoma]] | ||
*Ewing sarcoma | *[[Ewing sarcoma]] | ||
*Chondrosarcoma | *[[Chondrosarcoma]] | ||
*Fibrosarcoma | *[[Fibrosarcoma]] | ||
*Malignant fibrous histiocytoma | *[[Malignant fibrous histiocytoma]] | ||
*Plasma cell myeloma | *[[Plasma cell myeloma]] | ||
*Metastases | *[[Metastases]] | ||
|- | |- | ||
|} | |} | ||
| Line 139: | Line 139: | ||
|style="padding: 0 5px; background: #DCDCDC" | '''Osteolytic''' | |style="padding: 0 5px; background: #DCDCDC" | '''Osteolytic''' | ||
| | | | ||
*Renal cell cancer | *[[Renal cell cancer]] | ||
*Melanoma | *[[Melanoma]] | ||
*Multiple myeloma | *[[Multiple myeloma]] | ||
*Non-small cell lung cancer | *[[Non-small cell lung cancer]] | ||
*Thyroid cancer | *[[Thyroid cancer]] | ||
*Non-Hodgkin lymphoma | *[[Non-Hodgkin lymphoma]] | ||
*Langerhans cell histiocytosis | *[[Langerhans cell histiocytosis]] | ||
|style="padding: 0 5px; background: #DCDCDC" | '''Skull''' | |style="padding: 0 5px; background: #DCDCDC" | '''Skull''' | ||
| | | | ||
*Breast cancer | *[[Breast cancer]] | ||
*Lung cancer | *[[Lung cancer]] | ||
*Melanoma | *[[Melanoma]] | ||
*Prostate cancer | *[[Prostate cancer]] | ||
*Thyroid cancer (usually follicular) | *[[Thyroid cancer]] (usually follicular) | ||
*Renal cell cancer | *[[Renal cell cancer]] | ||
*Lymphoma | *[[Lymphoma]] | ||
*Leukaemia | *[[Leukaemia]] | ||
*Multiple myeloma | *[[Multiple myeloma]] | ||
|- | |- | ||
|style="padding: 0 5px; background: #DCDCDC" |'''Osteoblastic''' | |style="padding: 0 5px; background: #DCDCDC" |'''Osteoblastic''' | ||
| | | | ||
*Prostate cancer | *[[Prostate cancer]] | ||
*Carcinoid syndrome | *[[Carcinoid syndrome]] | ||
*Small cell lung cancer | *[[Small cell lung cancer]] | ||
*Hodgkin lymphoma | *[[Hodgkin lymphoma]] | ||
*Medulloblastoma | *[[Medulloblastoma]] | ||
|style="padding: 0 5px; background: #DCDCDC"| '''Vertebral''' | |style="padding: 0 5px; background: #DCDCDC"| '''Vertebral''' | ||
| | | | ||
*Breast cancer | *[[Breast cancer]] | ||
*Lung cancer | *[[Lung cancer]] | ||
*Prostate cancer | *[[Prostate cancer]] | ||
*Lymphoma | *[[Lymphoma]] | ||
*Renal cell carcinoma | *[[Renal cell carcinoma]] | ||
*Gastrointestinal tract malignancies | *[[Gastrointestinal tract]] malignancies | ||
* Melanoma | *[[Melanoma]] | ||
|- | |- | ||
|style="padding: 0 5px; background: #DCDCDC" | '''Mixed''' | |style="padding: 0 5px; background: #DCDCDC" | '''Mixed''' | ||
| | | | ||
*Breast cancer | *[[Breast cancer]] | ||
*Gastrointestinal cancers | *Gastrointestinal cancers | ||
*Squamous cancers (at most primary sites) | *Squamous cancers (at most primary sites) | ||
|style="padding: 0 5px; background: #DCDCDC" rowspan="2" | '''Distal appendicular''' | |style="padding: 0 5px; background: #DCDCDC" rowspan="2" | '''Distal appendicular''' | ||
| rowspan="2" | | | rowspan="2" | | ||
*Lung cancer | *[[Lung cancer]] | ||
*Breast cancer | *[[Breast cancer]] | ||
*Renal cell cancer | *[[Renal cell cancer]] | ||
*Prostate cancer | *[[Prostate cancer]] | ||
|- | |- | ||
|style="padding: 0 5px; background: #DCDCDC"| '''Other types ( "Blow out" and "Cookie type")''' | |style="padding: 0 5px; background: #DCDCDC"| '''Other types ( "Blow out" and "Cookie type")''' | ||
| | | | ||
*Renal cell carcinoma | *[[Renal cell carcinoma]] | ||
*Thyroid cancer | *[[Thyroid cancer]] | ||
*Hepatocellular | *[[Hepatocellular carcinoma]] | ||
*Bronchogenic carcinoma | *[[Bronchogenic carcinoma]] | ||
|} | |} | ||
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Latest revision as of 02:31, 6 November 2017
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Maria Fernanda Villarreal, M.D. [2]
Overview
Bone and cartilage tumors may be classified according to the WHO histological classification system into benign and malignant tumors, and categorized into 5 sub-types: cartilage tumors, osteogenic tumors, fibrohistiocytic tumors, notochordal tumors, hematopoietic tumors, and miscellaneous tumors.[1][2] In addition, bone and cartilage tumors may be sub-classified according to tumor location into 4 subtypes: diaphysis, metaphysis, epiphysis, and ungrouped/others.[3]
Classification
Bone and cartilage tumors may be classified by location, origin, and histopahological origin.
- Tumor location
- Diaphysis
- Epiphysis
- Metaphysis
- Other/Unclassifed
- Tumor nature
- Benign
- Malignant
- Origin
- Primary
- Secondary ( see "Secondary tumors classification" below)
- Histopathological origin
- Cartilage tumors
- Osteogenic tumors
- Fibrohistiocytic tumors
- Notochordal tumors
- Hematopoietic tumors
- Miscellaneous tumors.
- The table below summarizes the classification of bone and cartilage tumors according to histopathological origin, tumor location, and tumor nature.[1][2]
| Bone or cartilage mass classification Adapted from ICD-10/WHO (9180–9269)[3] | |||||||
|---|---|---|---|---|---|---|---|
| Osteogenic tumors: bone-forming tumors | Cartilage tumors: cartilage-forming tumors | Fibrogenic or fibrohistiocytic tumors | Cystic tumors | Others ( hematopoietic, notochordal, and neuroectodermal) | |||
| Histological Type | |||||||
|
|||||||
| Epiphysis | Diaphysis | Metaphysis | |||||
| Tumor Location | |||||||
| Benign | Malignant | ||||||
| Tumor Nature | |||||||
- The table below summarizes the classification of secondary bone tumors (also known as "metastases") according to location, and bone formation pattern.
| Secondary bone tumors: classification Adapted from Greenspan A et al. 2006 [4] | |||
|---|---|---|---|
| Bone formation pattern | Tumor location | ||
| Osteolytic | Skull |
| |
| Osteoblastic | Vertebral | ||
| Mixed |
|
Distal appendicular | |
| Other types ( "Blow out" and "Cookie type") | |||
References
- ↑ 1.0 1.1 Bone tumors. https://en.wikipedia.org/wiki/Bone_tumor Accessed on February 2, 2016
- ↑ 2.0 2.1 Alina Maria Sisu. On the Bone Tumours: Overview, Classification, Incidence, Histopathological Issues, Behavior and Review Using Literature Data. http://www.intechopen.com/books/histopathology-reviews-and-recent-advances/on-the-bone-tumours-overview-classification-incidence-histopathological-issues-behavior-and-review Accessed on February 2, 2016
- ↑ 3.0 3.1 Miller TT (2008). "Bone tumors and tumorlike conditions: analysis with conventional radiography". Radiology. 246 (3): 662–74. doi:10.1148/radiol.2463061038. PMID 18223119.
- ↑ Greenspan A, Jundt G, Remagen W. Differential diagnosis in orthopaedic oncology. Philadelphia : Lippincott Williams & Wilkins, c2007. (2006) ISBN:0781779308