Biliary dyskinesia medical therapy: Difference between revisions

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{{CMG}} {{AE}} {{SHA}}
{{CMG}} {{AE}} {{SHA}}
== Overview ==
== Overview ==
Medical therapy mostly includes of [[symptomatic treatment]] of [[abdominal pain]] and [[Intravenous therapy|IV]] [[Opiate|opiates]] are the drug of choice, although some studies have suggested that [[Opiate|opiates]] cause [[Sphincter of Oddi|SOD]] contraction.
Medical therapy mostly includes of [[symptomatic treatment]] of [[abdominal pain]] and [[Intravenous therapy|IV]] [[Opiate|opiates]] are the drug of choice, although some studies have suggested that [[Opiate|opiates]] cause [[sphincter of Oddi]] contraction.


== Medical Therapy ==
== Medical Therapy ==


* Medical therapy mostly includes of [[symptomatic treatment]] of [[abdominal pain]]:<ref name="pmid29132521">{{cite journal| author=Wilkins T, Agabin E, Varghese J, Talukder A| title=Gallbladder Dysfunction: Cholecystitis, Choledocholithiasis, Cholangitis, and Biliary Dyskinesia. | journal=Prim Care | year= 2017 | volume= 44 | issue= 4 | pages= 575-597 | pmid=29132521 | doi=10.1016/j.pop.2017.07.002 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=29132521  }} </ref><ref name="pmid16678563">{{cite journal| author=Behar J, Corazziari E, Guelrud M, Hogan W, Sherman S, Toouli J| title=Functional gallbladder and sphincter of oddi disorders. | journal=Gastroenterology | year= 2006 | volume= 130 | issue= 5 | pages= 1498-509 | pmid=16678563 | doi=10.1053/j.gastro.2005.11.063 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=16678563  }} </ref>
* Medical therapy mostly includes of [[symptomatic treatment]] of [[abdominal pain]]:
** [[Opiate|Opiates]] ([[Intravenous therapy|intravenous]]) are the drug of choice, although some studies have suggested that [[Opiate|opiates]] cause [[Sphincter of Oddi|sphincter of Oddi (SOD)]] contraction.
**[[Opiate|Opiates]] ([[Intravenous therapy|intravenous]]) are the drug of choice, although some studies have suggested that [[Opiate|opiates]] cause [[sphincter of Oddi]] contraction.
** [[Muscle relaxant|Muscle relaxants]] have been reported to be ineffective.
**[[Muscle relaxant|Muscle relaxants]] have been reported to be ineffective.
** [[Calcium channel blocker|Calcium channel blockers (CCB)]] have been reported to be ineffective.
**[[Calcium channel blocker|Calcium channel blockers (CCB)]] have been reported to be ineffective.
*** However, [[Calcium channel blocker|CCBs]] like [[nifedipine]] have been reported to have potential effect in improving the pain but [[headache]] and [[tachycardia]] are the [[Adverse effect (medicine)|adverse effects]].<ref name="pmid8470634">{{cite journal| author=Sand J, Nordback I, Koskinen M, Matikainen M, Lindholm TS| title=Nifedipine for suspected type II sphincter of Oddi dyskinesia. | journal=Am J Gastroenterol | year= 1993 | volume= 88 | issue= 4 | pages= 530-5 | pmid=8470634 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=8470634  }} </ref>
*** However, [[Calcium channel blocker|CCBs]] like [[nifedipine]] have been reported to have potential effect in improving the pain but [[headache]] and [[tachycardia]] are the [[Adverse effect (medicine)|adverse effects]].


* Alternative treatments that may be effective by a [[cholagogue]] effect (increases [[bile]] discharge from the [[Bile duct|biliary system]]), or a choleretic effect (increases [[bile]] [[secretion]] from the [[liver]]) include:<ref name="pmid12095476">{{cite journal| author=Toouli J| title=Biliary Dyskinesia. | journal=Curr Treat Options Gastroenterol | year= 2002 | volume= 5 | issue= 4 | pages= 285-291 | pmid=12095476 | doi=10.1007/s11938-002-0051-9 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=12095476  }} </ref>
* Alternative treatments that may be effective by a [[cholagogue]] effect (increases [[bile]] discharge from the [[Bile duct|biliary system]]), or a choleretic effect (increases [[bile]] [[secretion]] from the [[liver]]) include:
** Artichokes
** Artichokes
** [[Greater celandine|Celandine]]
** [[Greater celandine|Celandine]]
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** St. John’s Wort
** St. John’s Wort


* Other reported effective measures in biliary dyskinesia include:<ref name="pmid16804961">{{cite journal| author=Bistritz L, Bain VG| title=Sphincter of Oddi dysfunction: managing the patient with chronic biliary pain. | journal=World J Gastroenterol | year= 2006 | volume= 12 | issue= 24 | pages= 3793-802 | pmid=16804961 | doi=10.3748/wjg.v12.i24.3793 | pmc=4087924 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=16804961  }} </ref>
* Other reported effective measures in biliary dyskinesia include:
** [[Smoking cessation]]
**[[Smoking cessation]]
** Avoidance of fatty food
** Avoidance of fatty food
** Frequent meal consumption
** Frequent meal consumption
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[[Category:Needs content]]
[[Category:Needs content]]
<references />

Revision as of 14:08, 13 August 2020

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Shakiba Hassanzadeh, MD[2]

Overview

Medical therapy mostly includes of symptomatic treatment of abdominal pain and IV opiates are the drug of choice, although some studies have suggested that opiates cause sphincter of Oddi contraction.

Medical Therapy

  • Other reported effective measures in biliary dyskinesia include:
    • Smoking cessation
    • Avoidance of fatty food
    • Frequent meal consumption
    • Lying on the right side after meals
    • Weight loss
    • Increase in physical activity

References