Autoimmune polyendocrine syndrome CT: Difference between revisions

Jump to navigation Jump to search
Line 17: Line 17:


==CT scan==
==CT scan==
CT scan of the abdomen may be helpful in the diagnosis of autoimmune polyendocrine syndrome (APS). Findings on CT scan suggestive of adrenal insufficiency as seen in APS include:
CT scan findings in autoimmune polyendocrine syndrome (APS) depends upon the subtype of APS and the organ involved. In APS type 1, parathyroids and adrenal glands are often involved and may present with:
* Small adrenal remnants bilaterally suggestive of [[autoimmune adrenalitis]].
*CT scan of the abdomen may be helpful in the diagnosis of autoimmune polyendocrine syndrome (APS) type 1. Findings on CT scan suggestive of adrenal insufficiency as seen in APS include:
* Chronic cases of APS may have dense calcification in one or both adrenal beds.
** Small adrenal remnants bilaterally suggestive of [[autoimmune adrenalitis]].
* Atrophic adrenal glands - in [[idiopathic]] [[autoimmune]] Addison's disease.
** Chronic cases of APS may have dense calcification in one or both adrenal beds.
** Atrophic adrenal glands - in [[idiopathic]] [[autoimmune]] Addison's disease.
[[File:Addisons_CT.gif|frame|Bilateral adrenal diffuse enlargement (larger and mass like on the left side) showing calcfications.
[[File:Addisons_CT.gif|frame|Bilateral adrenal diffuse enlargement (larger and mass like on the left side) showing calcfications.
Source: Case courtesy of Dr Dalia Ibrahim, Radiopaedia.org, rID: 49318
Source: Case courtesy of Dr Dalia Ibrahim, Radiopaedia.org, rID: 49318
|center]]
|center]]


*Peripheral quantitative computed tomography (pQCT) may be helpful in the diagnosis of hypopparathyroidism.<ref name="pmid14557436">{{cite journal |vauthors=Chen Q, Kaji H, Iu MF, Nomura R, Sowa H, Yamauchi M, Tsukamoto T, Sugimoto T, Chihara K |title=Effects of an excess and a deficiency of endogenous parathyroid hormone on volumetric bone mineral density and bone geometry determined by peripheral quantitative computed tomography in female subjects |journal=J. Clin. Endocrinol. Metab. |volume=88 |issue=10 |pages=4655–8 |year=2003 |pmid=14557436 |doi=10.1210/jc.2003-030470 |url=}}</ref><ref name="pmid26234545">{{cite journal |vauthors=Cusano NE, Nishiyama KK, Zhang C, Rubin MR, Boutroy S, McMahon DJ, Guo XE, Bilezikian JP |title=Noninvasive Assessment of Skeletal Microstructure and Estimated Bone Strength in Hypoparathyroidism |journal=J. Bone Miner. Res. |volume=31 |issue=2 |pages=308–16 |year=2016 |pmid=26234545 |pmc=4832602 |doi=10.1002/jbmr.2609 |url=}}</ref>
*Peripheral quantitative computed tomography (pQCT) may be helpful in the diagnosis of hypopparathyroidism.<ref name="pmid14557436">{{cite journal |vauthors=Chen Q, Kaji H, Iu MF, Nomura R, Sowa H, Yamauchi M, Tsukamoto T, Sugimoto T, Chihara K |title=Effects of an excess and a deficiency of endogenous parathyroid hormone on volumetric bone mineral density and bone geometry determined by peripheral quantitative computed tomography in female subjects |journal=J. Clin. Endocrinol. Metab. |volume=88 |issue=10 |pages=4655–8 |year=2003 |pmid=14557436 |doi=10.1210/jc.2003-030470 |url=}}</ref><ref name="pmid26234545">{{cite journal |vauthors=Cusano NE, Nishiyama KK, Zhang C, Rubin MR, Boutroy S, McMahon DJ, Guo XE, Bilezikian JP |title=Noninvasive Assessment of Skeletal Microstructure and Estimated Bone Strength in Hypoparathyroidism |journal=J. Bone Miner. Res. |volume=31 |issue=2 |pages=308–16 |year=2016 |pmid=26234545 |pmc=4832602 |doi=10.1002/jbmr.2609 |url=}}</ref>

Revision as of 20:29, 25 September 2017

Autoimmune polyendocrine syndrome Microchapters

Home

Patient Information

Overview

Historical Perspective

Classification

Pathophysiology

Causes

Differentiating Autoimmune polyendocrine syndrome from other Diseases

Epidemiology and Demographics

Risk Factors

Screening

Natural History, Complications and Prognosis

Diagnosis

Diagnostic study of choice

History and Symptoms

Physical Examination

Laboratory Findings

Electrocardiogram

X Ray

CT

MRI

Echocardiography or Ultrasound

Other Imaging Findings

Other Diagnostic Studies

Treatment

Medical Therapy

Surgery

Primary Prevention

Secondary Prevention

Cost-Effectiveness of Therapy

Future or Investigational Therapies

Case Studies

Case #1

Autoimmune polyendocrine syndrome CT On the Web

Most recent articles

Most cited articles

Review articles

CME Programs

Powerpoint slides

Images

American Roentgen Ray Society Images of Autoimmune polyendocrine syndrome CT

All Images
X-rays
Echo & Ultrasound
CT Images
MRI

Ongoing Trials at Clinical Trials.gov

US National Guidelines Clearinghouse

NICE Guidance

FDA on Autoimmune polyendocrine syndrome CT

CDC on Autoimmune polyendocrine syndrome CT

Autoimmune polyendocrine syndrome CT in the news

Blogs on Autoimmune polyendocrine syndrome CT

Directions to Hospitals Treating Autoimmune polyendocrine syndrome

Risk calculators and risk factors for Autoimmune polyendocrine syndrome CT

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief:

Overview

There are no CT scan findings associated with [disease name].

OR

[Location] CT scan may be helpful in the diagnosis of [disease name]. Findings on CT scan suggestive of/diagnostic of [disease name] include [finding 1], [finding 2], and [finding 3].

OR

There are no CT scan findings associated with [disease name]. However, a CT scan may be helpful in the diagnosis of complications of [disease name], which include [complication 1], [complication 2], and [complication 3].

CT scan

CT scan findings in autoimmune polyendocrine syndrome (APS) depends upon the subtype of APS and the organ involved. In APS type 1, parathyroids and adrenal glands are often involved and may present with:

  • CT scan of the abdomen may be helpful in the diagnosis of autoimmune polyendocrine syndrome (APS) type 1. Findings on CT scan suggestive of adrenal insufficiency as seen in APS include:
    • Small adrenal remnants bilaterally suggestive of autoimmune adrenalitis.
    • Chronic cases of APS may have dense calcification in one or both adrenal beds.
    • Atrophic adrenal glands - in idiopathic autoimmune Addison's disease.
Bilateral adrenal diffuse enlargement (larger and mass like on the left side) showing calcfications. Source: Case courtesy of Dr Dalia Ibrahim, Radiopaedia.org, rID: 49318

References

  1. Chen Q, Kaji H, Iu MF, Nomura R, Sowa H, Yamauchi M, Tsukamoto T, Sugimoto T, Chihara K (2003). "Effects of an excess and a deficiency of endogenous parathyroid hormone on volumetric bone mineral density and bone geometry determined by peripheral quantitative computed tomography in female subjects". J. Clin. Endocrinol. Metab. 88 (10): 4655–8. doi:10.1210/jc.2003-030470. PMID 14557436.
  2. Cusano NE, Nishiyama KK, Zhang C, Rubin MR, Boutroy S, McMahon DJ, Guo XE, Bilezikian JP (2016). "Noninvasive Assessment of Skeletal Microstructure and Estimated Bone Strength in Hypoparathyroidism". J. Bone Miner. Res. 31 (2): 308–16. doi:10.1002/jbmr.2609. PMC 4832602. PMID 26234545.

Template:WH Template:WS