Autoimmune polyendocrine syndrome other diagnostic studies

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Akshun Kalia M.B.B.S.[2]

Overview

Other diagnostic studies for autoimmune polyendocrine syndrome (APS) include endoscopy with biopsy of upper gastrointestinal tract. Patients of APS may develop atrophic gastritis or celiac disease from autoantibodies against parietal cells or tissue transglutaminase. In patients with positive autoantibodies, endoscopy with biopsy may help in early diagnosis of atrophic gastritis or celiac disease.

Other Diagnostic Studies

Other diagnostic studies for autoimmune polyendocrine syndrome (APS) include endoscopy with biopsy of upper gastrointestinaI tract. Endoscopy with biopsy can be done to rule out other conditions associated with autoimmune polyendocrine syndrome. If patients of APS are positive for anti-tissue transglutaminase antibodies, endoscopy with biopsy may be helpful in diagnosing:[1][2]

References

  1. Niveloni S, Fiorini A, Dezi R, Pedreira S, Smecuol E, Vazquez H, Cabanne A, Boerr LA, Valero J, Kogan Z, Maurino E, Bai JC. (1998). "Usefulness of videoduodenoscopy and vital dye staining as indicators of mucosal atrophy of celiac disease: assessment of interobserver agreement". Gastrointestinal Endoscopy. 47 (3): 223–229. PMID 9580349.
  2. Mee A, Burke M, Vallon A, Newman J, Cotton P (1985). "Small bowel biopsy for malabsorption: comparison of the diagnostic adequacy of endoscopic forceps and capsule biopsy specimens". Br Med J (Clin Res Ed). 291 (6498): 769–72. PMID 3929934.

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