Aspergillosis epidemiology and demographics: Difference between revisions

Jump to navigation Jump to search
m (Changes made per Mahshid's request)
 
(19 intermediate revisions by 5 users not shown)
Line 1: Line 1:
__NOTOC__
{{Aspergillosis}}
{{Aspergillosis}}
{{CMG}}; '''Associate Editor-In-Chief:''' {{CZ}}
{{CMG}} {{AE}} {{YD}}; {{HL}}; {{SSK}}
 
==Overview==
==Overview==
Mallards and other ducks are particularly susceptible to '''''Aspergillosis''''' as they will often resort to poor food sources during bad weather.
The true incidence of aspergillosis is unknown since aspergillosis is not a reportable disease in the USA.<ref name="pmid23210682">{{cite journal| author=Denning DW, Pleuvry A, Cole DC| title=Global burden of allergic bronchopulmonary aspergillosis with asthma and its complication chronic pulmonary aspergillosis in adults. | journal=Med Mycol | year= 2013 | volume= 51 | issue= 4 | pages= 361-70 | pmid=23210682 | doi=10.3109/13693786.2012.738312 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=23210682  }} </ref> The annual incidence of allergic bronchopulmonary aspergillosis is estimated to be 5 million cases worldwide.<ref name="pmid23210682">{{cite journal| author=Denning DW, Pleuvry A, Cole DC| title=Global burden of allergic bronchopulmonary aspergillosis with asthma and its complication chronic pulmonary aspergillosis in adults. | journal=Med Mycol | year= 2013 | volume= 51 | issue= 4 | pages= 361-70 | pmid=23210682 | doi=10.3109/13693786.2012.738312 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=23210682  }} </ref> In contrast, invasive aspergillosis is much less common with an incidence of approximately 1 to 2 cases per 100,000 individuals. There is no gender predilection for the development of aspergillosis. Individuals of all age groups may be affected with aspergillosis. Elderly patients with long-standing chronic lung diseases and neonates are more likely to develop aspergillosis. With the advancement of immunosuppressive therapy and higher rates of transplantation, the incidence and detection of aspergillosis is increasing in developed countries.<ref name="CDC">Definition of Aspergillosis -  Centers for Disease Control and Prevention (CDC) http://www.cdc.gov/fungal/diseases/aspergillosis/statistics.html Accessed on Feb 8 2016</ref>


Albeit relatively rare in humans, aspergillosis is a common and dangerous infection in birds, particularly in pet parrots and parakeets.
==Epidemiology and Demographics==
===Incidence===
*The true incidence of aspergillosis is unknown since aspergillosis is not a reportable disease in the USA.<ref name="pmid23210682">{{cite journal| author=Denning DW, Pleuvry A, Cole DC| title=Global burden of allergic bronchopulmonary aspergillosis with asthma and its complication chronic pulmonary aspergillosis in adults. | journal=Med Mycol | year= 2013 | volume= 51 | issue= 4 | pages= 361-70 | pmid=23210682 | doi=10.3109/13693786.2012.738312 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=23210682  }} </ref>
*The annual incidence of allergic bronchopulmonary aspergillosis is estimated to be 5 million cases worldwide.<ref name="pmid23210682">{{cite journal| author=Denning DW, Pleuvry A, Cole DC| title=Global burden of allergic bronchopulmonary aspergillosis with asthma and its complication chronic pulmonary aspergillosis in adults. | journal=Med Mycol | year= 2013 | volume= 51 | issue= 4 | pages= 361-70 | pmid=23210682 | doi=10.3109/13693786.2012.738312 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=23210682  }} </ref>
*Approximately 2.5% of adults who have asthma also have allergic bronchopulmonary aspergillosis.<ref name="pmid23210682">{{cite journal| author=Denning DW, Pleuvry A, Cole DC| title=Global burden of allergic bronchopulmonary aspergillosis with asthma and its complication chronic pulmonary aspergillosis in adults. | journal=Med Mycol | year= 2013 | volume= 51 | issue= 4 | pages= 361-70 | pmid=23210682 | doi=10.3109/13693786.2012.738312 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=23210682  }} </ref>
*In contrast, invasive aspergillosis is much less common with an incidence of approximately 1 to 2 cases per 100,000 individuals.<ref name="pmid9827260">{{cite journal| author=Rees JR, Pinner RW, Hajjeh RA, Brandt ME, Reingold AL| title=The epidemiological features of invasive mycotic infections in the San Francisco Bay area, 1992-1993: results of population-based laboratory active surveillance. | journal=Clin Infect Dis | year= 1998 | volume= 27 | issue= 5 | pages= 1138-47 | pmid=9827260 | doi= | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=9827260  }} </ref>
*Invasive aspergillosis is the most common type of fungal infection among stem cell transplant recipients (5% to 10%) and the second most common type of fungal infection among solid organ transplant recipients (5% to 25%).<ref name="pmid20218876">{{cite journal| author=Pappas PG, Alexander BD, Andes DR, Hadley S, Kauffman CA, Freifeld A et al.| title=Invasive fungal infections among organ transplant recipients: results of the Transplant-Associated Infection Surveillance Network (TRANSNET). | journal=Clin Infect Dis | year= 2010 | volume= 50 | issue= 8 | pages= 1101-11 | pmid=20218876 | doi=10.1086/651262 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=20218876  }} </ref>


While there is no connection between Aspergillosis and the H5N1 strain of [[Avian Influenza]] (commonly called "[[Avian flu|bird flu]]"), the rapid die-offs it causes can spark fears of a [[bird-flu]] outbreak in the communities where the die-offs occur. There is no outwardly visible sign off the fungal infection as the cause; laboratory analysis is the only way to prove or disprove [[bird-flu]] or Aspergillosis.
===Mortality Rate===
==Surveillance==
*The mortality rate of aspergillosis varies according to the clinical syndrome.
  No national surveillance exists. Active surveillance is being conducted among hematopoietic stem cell and solid organ transplant recipients in selected U.S. hospitals.
*Allergic bronchopulmonary aspergillosis and allergic ''Aspergillus'' sinusitis rarely result in mortality.
*In contrast, the mortality rate of either invasive aspergillosis or chronic necrotizing pulmonary aspergillosis is high and may be up to 40% to 90%.<ref name="CDC">Definition of Aspergillosis - Centers for Disease Control and Prevention (CDC) http://www.cdc.gov/fungal/diseases/aspergillosis/statistics.html Accessed on Feb 8 2016</ref>
 
===Gender===
*There is no gender predilection for the development of aspergillosis.<ref name="CDC">Definition of Aspergillosis -  Centers for Disease Control and Prevention (CDC) http://www.cdc.gov/fungal/diseases/aspergillosis/statistics.html Accessed on Feb 8 2016</ref>
 
===Age===
*Individuals of all age groups may be affected with aspergillosis.
*Elderly patients with long-standing chronic lung diseases are more likely to develop aspergillosis.
*Neonates are at increased risk of cutaneous aspergillosis.
 
===Developed Countries===
*With the advancement of immunosuppressive therapy and higher rates of transplantation, the incidence and detection of aspergillosis is increasing in developed countries.<ref name="CDC">Definition of Aspergillosis - Centers for Disease Control and Prevention (CDC) http://www.cdc.gov/fungal/diseases/aspergillosis/statistics.html Accessed on Feb 8 2016</ref>


==References==
==References==
Line 15: Line 35:


[[Category:Fungal diseases]]
[[Category:Fungal diseases]]
[[Category:Infectious disease]]
[[de:Aspergillose]]
[[fr:Aspergillose]]
[[hr:Aspergiloza]]
[[nl:Aspergillose]]
[[pl:Aspergiloza]]
[[pt:Aspergilose]]
[[uk:Аспергільоз]]
}
{{WH}}
{{WS}}

Latest revision as of 17:01, 18 September 2017

Aspergillosis Microchapters

Home

Patient Information

Overview

Historical Perspective

Classification

Pathophysiology

Causes

Differentiating Aspergillosis from other Diseases

Epidemiology and Demographics

Risk Factors

Natural History, Complications and Prognosis

Diagnosis

Diagnostic Criteria

History and Symptoms

Physical Examination

Laboratory Findings

Chest X Ray

CT

Other Diagnostic Studies

Treatment

Medical Therapy

Surgery

Primary Prevention

Future or Investigational Therapies

Case Studies

Case #1

Aspergillosis epidemiology and demographics On the Web

Most recent articles

cited articles

Review articles

CME Programs

Powerpoint slides

Images

American Roentgen Ray Society Images of Aspergillosis epidemiology and demographics

All Images
X-rays
Echo & Ultrasound
CT Images
MRI

Ongoing Trials at Clinical Trials.gov

US National Guidelines Clearinghouse

NICE Guidance

FDA on Aspergillosis epidemiology and demographics

CDC on Aspergillosis epidemiology and demographics

Aspergillosis epidemiology and demographics in the news

Blogs on Aspergillosis epidemiology and demographics

Aspergillosis

Risk calculators and risk factors for Aspergillosis epidemiology and demographics

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Yazan Daaboul, M.D.; Haytham Allaham, M.D. [2]; Serge Korjian M.D.

Overview

The true incidence of aspergillosis is unknown since aspergillosis is not a reportable disease in the USA.[1] The annual incidence of allergic bronchopulmonary aspergillosis is estimated to be 5 million cases worldwide.[1] In contrast, invasive aspergillosis is much less common with an incidence of approximately 1 to 2 cases per 100,000 individuals. There is no gender predilection for the development of aspergillosis. Individuals of all age groups may be affected with aspergillosis. Elderly patients with long-standing chronic lung diseases and neonates are more likely to develop aspergillosis. With the advancement of immunosuppressive therapy and higher rates of transplantation, the incidence and detection of aspergillosis is increasing in developed countries.[2]

Epidemiology and Demographics

Incidence

  • The true incidence of aspergillosis is unknown since aspergillosis is not a reportable disease in the USA.[1]
  • The annual incidence of allergic bronchopulmonary aspergillosis is estimated to be 5 million cases worldwide.[1]
  • Approximately 2.5% of adults who have asthma also have allergic bronchopulmonary aspergillosis.[1]
  • In contrast, invasive aspergillosis is much less common with an incidence of approximately 1 to 2 cases per 100,000 individuals.[3]
  • Invasive aspergillosis is the most common type of fungal infection among stem cell transplant recipients (5% to 10%) and the second most common type of fungal infection among solid organ transplant recipients (5% to 25%).[4]

Mortality Rate

  • The mortality rate of aspergillosis varies according to the clinical syndrome.
  • Allergic bronchopulmonary aspergillosis and allergic Aspergillus sinusitis rarely result in mortality.
  • In contrast, the mortality rate of either invasive aspergillosis or chronic necrotizing pulmonary aspergillosis is high and may be up to 40% to 90%.[2]

Gender

  • There is no gender predilection for the development of aspergillosis.[2]

Age

  • Individuals of all age groups may be affected with aspergillosis.
  • Elderly patients with long-standing chronic lung diseases are more likely to develop aspergillosis.
  • Neonates are at increased risk of cutaneous aspergillosis.

Developed Countries

  • With the advancement of immunosuppressive therapy and higher rates of transplantation, the incidence and detection of aspergillosis is increasing in developed countries.[2]

References

  1. 1.0 1.1 1.2 1.3 1.4 Denning DW, Pleuvry A, Cole DC (2013). "Global burden of allergic bronchopulmonary aspergillosis with asthma and its complication chronic pulmonary aspergillosis in adults". Med Mycol. 51 (4): 361–70. doi:10.3109/13693786.2012.738312. PMID 23210682.
  2. 2.0 2.1 2.2 2.3 Definition of Aspergillosis - Centers for Disease Control and Prevention (CDC) http://www.cdc.gov/fungal/diseases/aspergillosis/statistics.html Accessed on Feb 8 2016
  3. Rees JR, Pinner RW, Hajjeh RA, Brandt ME, Reingold AL (1998). "The epidemiological features of invasive mycotic infections in the San Francisco Bay area, 1992-1993: results of population-based laboratory active surveillance". Clin Infect Dis. 27 (5): 1138–47. PMID 9827260.
  4. Pappas PG, Alexander BD, Andes DR, Hadley S, Kauffman CA, Freifeld A; et al. (2010). "Invasive fungal infections among organ transplant recipients: results of the Transplant-Associated Infection Surveillance Network (TRANSNET)". Clin Infect Dis. 50 (8): 1101–11. doi:10.1086/651262. PMID 20218876.

Template:Mycoses