Arachnoid cyst natural history, complications and prognosis

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: José Eduardo Riceto Loyola Junior, M.D.[2]

Overview

Prognosis of arachnoid cyst is generally excellent and is usually associated with a benign disease course, despite being symptomatic in a few patients.

Natural History

  • Arachnoid cyst usually develops asymptomatically and remains asymptomatic in most patients through their lifetime;
  • Most are found incidentally;
  • In a few patients they may have: headaches, hydrocephalus, ataxia/gait imbalance, seizures, dizziness, visual changes, hearing loss, vertigo, nausea/vomiting, speech abnormalities, cervical myelopathy with syrinx;
  • In a paper from 2013, 203 patients with arachnoid cysts were followed up, with only 5 patients presenting with enlargement of the cyst and only 2 developing symptoms that could be due to the arachnoid cyst. [1]

Complications

Arachnoid cysts may, rarely, enlarge and complicate with the symptoms above (such as hydrocephalus, seizures, hearing loss, visual changes and cervical myelopathy). In a very restricted selection of cases they may be surgically treatment, but surgery may occasionally result in complications including:

  • Subdural hygroma;
  • Subdural hematoma;
  • Pseudomeningomyelocele;
  • Subdural empyema;
  • Wound complications;
  • Meningitis;
  • Hydrocephalus;
  • Seizure;
  • Need for more surgical procedures after a failed initial surgical attempt.[1]

Prognosis

  • The prognosis of arachnoid cyst is often good, and in the majority of cases won't demand treatment.
  • Without treatment, in a few cases the symptoms may worsen over time.
  • Surgical decompression of the arachnoid cyst yielded a reduction in 66% of the patients of less than 50% of the preoperative volume. 82% were asymptomatic after the procedure, while 12% reported no relief and 6% experienced worsening of the symptoms. [2]

References

  1. 1.0 1.1 Al-Holou, Wajd N., et al. "Prevalence and natural history of arachnoid cysts in adults." Journal of Neurosurgery 118.2 (2013): 222-231.
  2. Helland, Christian A., and Knut Wester. "A population-based study of intracranial arachnoid cysts: clinical and neuroimaging outcomes following surgical cyst decompression in children." Journal of Neurosurgery: Pediatrics 105.5 (2006): 385-390.